This study is designed as a comparative clinical trial to evaluate the efficacy of Arka Kshara against the established standard, Apamarga Kshara, in the management of Karnini Yoni Vyapad, which correlates clinically with Cervical Erosion (Cervical Ectopy). The research focuses on the therapeutic potential of Kshara Karma—utilizing the Dahana, Pachana, and Lekhana properties of these alkaline preparations—to facilitate the removal of abnormal columnar epithelium and promote the regeneration of healthy squamous epithelial layers. While Apamarga Kshara serves as the traditional gold standard, this study seeks to validate Arka Kshara (derived from Calotropis gigantea) as a novel alternative that may offer superior anti-inflammatory and wound-healing benefits with minimal local tissue damage.

To ensure standardized internal support and systemic detoxification, both treatment groups will receive Nimbadi Guggulu as an adjuvant. This combination is intended to provide Krimighna (antimicrobial) and Shothahara (anti-inflammatory) effects, thereby reducing the risk of infection and enhancing the Ropana (healing) process. Clinical outcomes will be measured by the reduction of symptoms such as excessive vaginal discharge, post-coital bleeding, and backache, alongside the visual observation of cervical tissue repair. Ultimately, the study aims to establish a safe, effective, and minimally invasive Ayurvedic protocol for women of reproductive age suffering from this common gynecological condition.