| CTRI Number |
CTRI/2026/03/106775 [Registered on: 23/03/2026] Trial Registered Prospectively |
| Last Modified On: |
13/03/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Homeopathy |
| Study Design |
Single Arm Study |
|
Public Title of Study
|
Boenninghausens Therapeutic Pocket Book Repertory in Bronchial Asthma |
|
Scientific Title of Study
|
Effectiveness of Individualized Homoeopathic Medicine in Boenninghausens Therapeutic Pocket Book in Bronchial Asthma A Pre-Post Interventional Study |
| Trial Acronym |
Nil |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Dalal Kinal Mahendrakumar |
| Designation |
Postgraduate Trainee |
| Affiliation |
National Institute of Homoeopathy Delhi |
| Address |
National Institute of Homoeopathy Delhi Department of Case Taking and Repertory. OPD 125, Sector A-8, Chaudhary Ramdev Chowk, Narela, Delhi-110040
North West DELHI 110040 India |
| Phone |
9106751505 |
| Fax |
|
| Email |
kinaldalal99@gmail.com |
|
Details of Contact Person Scientific Query
|
| Name |
K K Rathibha |
| Designation |
Assistant Professor |
| Affiliation |
National Institute of Homoeopathy Delhi |
| Address |
National Institute of Homoeopathy Delhi Department of Case Taking and Repertory. OPD 125, Sector A-8, Chaudhary Ramdev Chowk, Narela, Delhi-110040
North West DELHI 110040 India |
| Phone |
9745524911 |
| Fax |
|
| Email |
Rathibha20Rnair@gmail.com |
|
Details of Contact Person Public Query
|
| Name |
Dr Dalal Kinal Mahendrakumar |
| Designation |
Postgraduate Trainee |
| Affiliation |
National Institute of Homoeopathy Delhi |
| Address |
National Institute of Homoeopathy Delhi Department of Case Taking and Repertory. OPD 125, Sector A-8, Chaudhary Ramdev Chowk, Narela, Delhi-110040
North West DELHI 110040 India |
| Phone |
9106751505 |
| Fax |
|
| Email |
kinaldalal99@gmail.com |
|
|
Source of Monetary or Material Support
|
| National Institute of Homoeopathy Delhi
Sector A8 Chaudhary Ramdev Chowk, Narela, Delhi 110040 |
|
|
Primary Sponsor
|
| Name |
DR DALAL KINAL MAHENDRAKUMAR |
| Address |
National Institute of Homoeopathy Delhi, Sector A-8, Chaudhary Ramdev Chowk, Narela, Delhi-110040 |
| Type of Sponsor |
Other [SELF] |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Dalal Kinal Mahendrakumar |
National Institute of Homoeopathy Delhi |
Department of Case Taking and Repertory OPD 125 Sector A8 Chaudhary Ramdev Chowk Narela 110040 North West DELHI |
09106751505
kinaldalal99@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional ethical committee |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: J453||Mild persistent asthma, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Intervention |
Individualised Homoeopathic Treatment for 3 months |
selection of proper potency and dose and repetition as per homoeopathic principles. |
| Comparator Agent |
NOT APPLICABLE |
NOT APPLICABLE |
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
60.00 Year(s) |
| Gender |
Both |
| Details |
1 Patients diagnosed with Bronchial Asthma with an ACT score equal or less than 19 not well controlled asthma at baseline will be included in the study.
2 Subjects who are on the inhaler and nebulizer medication related to asthma.
3 Subjects who are willing to participate and ready to sign written informed consent for the same
|
|
| ExclusionCriteria |
| Details |
1 Subjects with co-morbid conditions like GERD, Otitis media, Bronchitis, Foreign body obstructions.
2 Subjects with Acute severe asthma, and Status asthmaticus
3 Subjects on any other system of medication or those who have undergone any surgical interventions.
4 Subjects complicated with other organic and psychiatric diseases.
5 Subjects included pregnant and lactating women.
|
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
1)Effectiveness of the treatment in each patient will be done on the basis of either increasing or decreasing in the total number of scores using ACT with a comparative analysis between baseline and after 3rd month.
2)Identification and shortlisting of the most frequently prescribed and clinically effective homoeopathic medicines, along with their characteristic indications, in the management of Bronchial Asthma.
|
Assessed at baseline and after 3 months of intervention. |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| NOT APPLICABLE |
NOT APPLICABLE |
|
|
Target Sample Size
|
Total Sample Size="40" Sample Size from India="40"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
Phase 3 |
|
Date of First Enrollment (India)
|
26/03/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="0" Months="6" Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Yet Recruiting |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Bronchial asthma is a chronic respiratory disorder characterized by airway inflammation, airway hyper-responsiveness, and reversible airway obstruction. It is a growing global health problem affecting millions of people and significantly impacting the quality of life of patients. According to the World Health Organization, asthma is often underdiagnosed and undertreated, especially in low- and middle-income countries, leading to complications such as sleep disturbance, fatigue, poor concentration, and in severe cases hospitalization or death.
In India, homoeopathy is widely used as a complementary and alternative system of medicine. Homoeopathic treatment focuses on individualization and the principle of symptom similarity for remedy selection. Samuel Hahnemann, the founder of homoeopathy, emphasized the importance of totality of symptoms for selecting the most suitable medicine. Clemens Maria Franz von Boenninghausen developed the Boenninghausen’s Therapeutic Pocket Book, an important repertory that assists physicians in selecting the similimum by analyzing location, sensation, modalities, and concomitant symptoms.
The present study aims to evaluate the effectiveness of individualized homoeopathic medicines selected through Boenninghausen’s Therapeutic Pocket Book in patients suffering from bronchial asthma. The effectiveness will be measured using the Asthma Control Test (ACT), by comparing ACT scores before and after treatment.
A pre-post interventional clinical study will be conducted at the National Institute of Homoeopathy, where patients attending the outpatient department with bronchial asthma will be enrolled. A total of 40 participants aged 18 to 60 years with ACT score equal or less than 19 will be included in the study. Individualized homoeopathic medicines will be prescribed after proper case taking and repertorization using Boenninghausen’s Therapeutic Pocket Book. Patients will be followed up every 15 days for three months, and ACT scores will be assessed at baseline and monthly intervals.
The collected data will be analyzed using appropriate statistical methods such as paired t-test or Wilcoxon signed-rank test depending on the distribution of data. The study also aims to identify the most frequently prescribed homoeopathic medicines and evaluate their clinical indications in bronchial asthma management.
This research intends to contribute to the scientific evaluation of homoeopathic treatment in asthma and explore the usefulness of Boenninghausen’s repertory as a clinical tool in selecting effective individualized remedies. |