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CTRI Number  CTRI/2026/03/106775 [Registered on: 23/03/2026] Trial Registered Prospectively
Last Modified On: 13/03/2026
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Homeopathy 
Study Design  Single Arm Study 
Public Title of Study   Boenninghausens Therapeutic Pocket Book Repertory in Bronchial Asthma 
Scientific Title of Study   Effectiveness of Individualized Homoeopathic Medicine in Boenninghausens Therapeutic Pocket Book in Bronchial Asthma A Pre-Post Interventional Study 
Trial Acronym  Nil 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Dalal Kinal Mahendrakumar 
Designation  Postgraduate Trainee 
Affiliation  National Institute of Homoeopathy Delhi 
Address  National Institute of Homoeopathy Delhi Department of Case Taking and Repertory. OPD 125, Sector A-8, Chaudhary Ramdev Chowk, Narela, Delhi-110040

North West
DELHI
110040
India 
Phone  9106751505  
Fax    
Email  kinaldalal99@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  K K Rathibha  
Designation  Assistant Professor  
Affiliation  National Institute of Homoeopathy Delhi 
Address  National Institute of Homoeopathy Delhi Department of Case Taking and Repertory. OPD 125, Sector A-8, Chaudhary Ramdev Chowk, Narela, Delhi-110040

North West
DELHI
110040
India 
Phone  9745524911  
Fax    
Email  Rathibha20Rnair@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Dr Dalal Kinal Mahendrakumar 
Designation  Postgraduate Trainee 
Affiliation  National Institute of Homoeopathy Delhi 
Address  National Institute of Homoeopathy Delhi Department of Case Taking and Repertory. OPD 125, Sector A-8, Chaudhary Ramdev Chowk, Narela, Delhi-110040

North West
DELHI
110040
India 
Phone  9106751505  
Fax    
Email  kinaldalal99@gmail.com  
 
Source of Monetary or Material Support  
National Institute of Homoeopathy Delhi Sector A8 Chaudhary Ramdev Chowk, Narela, Delhi 110040 
 
Primary Sponsor  
Name  DR DALAL KINAL MAHENDRAKUMAR 
Address  National Institute of Homoeopathy Delhi, Sector A-8, Chaudhary Ramdev Chowk, Narela, Delhi-110040  
Type of Sponsor  Other [SELF] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Dalal Kinal Mahendrakumar  National Institute of Homoeopathy Delhi  Department of Case Taking and Repertory OPD 125 Sector A8 Chaudhary Ramdev Chowk Narela 110040
North West
DELHI 
09106751505

kinaldalal99@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional ethical committee  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: J453||Mild persistent asthma,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Individualised Homoeopathic Treatment for 3 months  selection of proper potency and dose and repetition as per homoeopathic principles. 
Comparator Agent  NOT APPLICABLE  NOT APPLICABLE 
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  60.00 Year(s)
Gender  Both 
Details  1 Patients diagnosed with Bronchial Asthma with an ACT score equal or less than 19 not well controlled asthma at baseline will be included in the study.
2 Subjects who are on the inhaler and nebulizer medication related to asthma.
3 Subjects who are willing to participate and ready to sign written informed consent for the same
 
 
ExclusionCriteria 
Details  1 Subjects with co-morbid conditions like GERD, Otitis media, Bronchitis, Foreign body obstructions.
2 Subjects with Acute severe asthma, and Status asthmaticus
3 Subjects on any other system of medication or those who have undergone any surgical interventions.
4 Subjects complicated with other organic and psychiatric diseases.
5 Subjects included pregnant and lactating women.
 
 
Method of Generating Random Sequence   Not Applicable 
Method of Concealment   Not Applicable 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
1)Effectiveness of the treatment in each patient will be done on the basis of either increasing or decreasing in the total number of scores using ACT with a comparative analysis between baseline and after 3rd month.
2)Identification and shortlisting of the most frequently prescribed and clinically effective homoeopathic medicines, along with their characteristic indications, in the management of Bronchial Asthma.
 
Assessed at baseline and after 3 months of intervention. 
 
Secondary Outcome  
Outcome  TimePoints 
NOT APPLICABLE   NOT APPLICABLE 
 
Target Sample Size   Total Sample Size="40"
Sample Size from India="40" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   Phase 3 
Date of First Enrollment (India)   26/03/2026 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="0"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)   Not Yet Recruiting 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

Bronchial asthma is a chronic respiratory disorder characterized by airway inflammation, airway hyper-responsiveness, and reversible airway obstruction. It is a growing global health problem affecting millions of people and significantly impacting the quality of life of patients. According to the World Health Organization, asthma is often underdiagnosed and undertreated, especially in low- and middle-income countries, leading to complications such as sleep disturbance, fatigue, poor concentration, and in severe cases hospitalization or death.

In India, homoeopathy is widely used as a complementary and alternative system of medicine. Homoeopathic treatment focuses on individualization and the principle of symptom similarity for remedy selection. Samuel Hahnemann, the founder of homoeopathy, emphasized the importance of totality of symptoms for selecting the most suitable medicine. Clemens Maria Franz von Boenninghausen developed the Boenninghausen’s Therapeutic Pocket Book, an important repertory that assists physicians in selecting the similimum by analyzing location, sensation, modalities, and concomitant symptoms.

The present study aims to evaluate the effectiveness of individualized homoeopathic medicines selected through Boenninghausen’s Therapeutic Pocket Book in patients suffering from bronchial asthma. The effectiveness will be measured using the Asthma Control Test (ACT), by comparing ACT scores before and after treatment.

A pre-post interventional clinical study will be conducted at the National Institute of Homoeopathy, where patients attending the outpatient department with bronchial asthma will be enrolled. A total of 40 participants aged 18 to 60 years with ACT score  equal or less than 19 will be included in the study. Individualized homoeopathic medicines will be prescribed after proper case taking and repertorization using Boenninghausen’s Therapeutic Pocket Book. Patients will be followed up every 15 days for three months, and ACT scores will be assessed at baseline and monthly intervals.

The collected data will be analyzed using appropriate statistical methods such as paired t-test or Wilcoxon signed-rank test depending on the distribution of data. The study also aims to identify the most frequently prescribed homoeopathic medicines and evaluate their clinical indications in bronchial asthma management.

This research intends to contribute to the scientific evaluation of homoeopathic treatment in asthma and explore the usefulness of Boenninghausen’s repertory as a clinical tool in selecting effective individualized remedies.

 
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