| CTRI Number |
CTRI/2026/01/102341 [Registered on: 28/01/2026] Trial Registered Prospectively |
| Last Modified On: |
24/01/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Physiotherapy (Not Including YOGA) |
| Study Design |
Randomized, Parallel Group Trial |
|
Public Title of Study
|
TO CHECK THE EFFECT OF ECCENTRIC QUADRICEPS TRAINING IN ACL REPAIR N FOR COLLEGE GOING FOOTBALL PLAYERS |
|
Scientific Title of Study
|
EXAMINING THE EFFICACY OF CROSS ECCENTRIC QUADRICEPS STRENGTH TRAINING ON FUNCTIONAL DISABILITY AMONG COLLEGIATE FOOTBALL PLAYERS WITH ACL RECONSTRUCTION: AN EXPERIMENTAL STUDY |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
SUHANI BHATI |
| Designation |
POST GRADUATE STUDENT |
| Affiliation |
Prakash institute of physiotherapy rehabilitation & Allied medical sciences |
| Address |
PRAKASH INSTITUTE OF PHYSIOTHERAPY REHABILITATION AND ALLIED MEDICAL SCIENCES
PLOT NO 9A POCKET P2 BUILDERS AREA SECTOR OMEGA 1 GREATER NOIDA
PRAKASH INSTITUTE OF PHYSIOTHERAPY REHABILITATION AND ALLIED MEDICAL SCIENCES
PLOT NO 9A POCKET P2 BUILDERS AREA SECTOR OMEGA 1 GREATER NOIDA
Gautam Buddha Nagar
UTTAR PRADESH
201310
India |
| Phone |
9354907402 |
| Fax |
|
| Email |
suhanibhati77@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
DR MEGHA BHARDWAJ PT |
| Designation |
ASSISTANT PROFESSOR |
| Affiliation |
Prakash Institute of Physiotherapy Rehabilitation & Allied medical sciences |
| Address |
PRAKASH INSTITUTE OF PHYSIOTHERAPY REHABILITATION AND ALLIED MEDICAL SCIENCES
PLOT NO 9A POCKET P2 BUILDERS AREA SECTOR OMEGA 1 GREATER NOIDA
Gautam Buddha Nagar
UTTAR PRADESH
201310
India |
| Phone |
7983720114 |
| Fax |
|
| Email |
meghbhardwaj116@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
DR RENU PT |
| Designation |
Assistant Professor |
| Affiliation |
Prakash Institute of Physiotherapy Rehabilitation & Allied medical sciences |
| Address |
PRAKASH INSTITUTE OF PHYSIOTHERAPY REHABILITATION AND ALLIED MEDICAL SCIENCES
PLOT NO 9A POCKET P2 BUILDERS AREA SECTOR OMEGA 1 GREATER NOIDA
Gautam Buddha Nagar
UTTAR PRADESH
201310
India |
| Phone |
9810701063 |
| Fax |
|
| Email |
cuterenudaksh111@gmail.com |
|
|
Source of Monetary or Material Support
|
|
|
Primary Sponsor
|
| Name |
SUHANI BHATI |
| Address |
PRAKASH INSTITUTE OF PHYSIOTHERAPY REHABILITATION AND ALLIED MEDICAL SCIENCES
PLOT NO 9A POCKET P2 BUILDERS AREA SECTOR OMEGA 1 GREATER NOIDA |
| Type of Sponsor |
Other [SELF] |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| DR UTSAV RAJ |
MOBILITY RX PHYSIOTHERAPY AND REHABILITATION CENTRE |
physiotherapy department ground floor room no G03 GREATER NOIDA WEST
Gautam Buddha Nagar
UTTAR PRADESH |
9102447501
Help.rccare@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Prakash Institute of physiotherapy rehabilitation and allied medical sciences |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: M708||Other soft tissue disorders related to use, overuse and pressure, (2) ICD-10 Condition: M708||Other soft tissue disorders related to use, overuse and pressure, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Intervention |
Group A (Experimental group)
Cross eccentric quadriceps strength training program |
The subjects allocated to Group A (Experimental Group) received a structured cross eccentric quadriceps strength training program in addition to conventional post-ACL reconstruction rehabilitation. The intervention was administered for a total duration of 12 weeks, with three supervised sessions per week, and each session lasted approximately 60 minutes. Each session began with a standardized warm-up consisting of light aerobic activities such as stationary cycling or brisk walking, followed by dynamic stretching of the lower limb muscles to prepare the knee joint for loading activities.
The main training component focused specifically on eccentric activation of the quadriceps muscle of the operated limb. Exercises included single-leg eccentric squats, eccentric step-down exercises, forward and lateral lunges emphasizing slow controlled lowering, and resisted knee extensions with a prolonged eccentric phase. The eccentric phase of each exercise was deliberately slowed (approximately 3–5 seconds) to maximize muscle loading and neuromuscular adaptation. Training intensity was maintained at a moderate level and was progressed gradually by increasing resistance, repetitions, or exercise complexity based on individual tolerance and performance. Adequate rest intervals of 60–90 seconds were provided between sets. Each session concluded with a cool-down phase involving static stretching of the quadriceps, hamstrings, and calf muscles. Participants were continuously monitored for pain, swelling, or any adverse responses throughout the intervention period. |
| Comparator Agent |
Group B (Control group)
Standard post -Acl reconstruction program |
The subjects assigned to Group B (Control Group) continued with a standard post-ACL reconstruction rehabilitation program for the same duration of 12 weeks, with three sessions per week, each lasting approximately 60 minutes. The conventional rehabilitation protocol emphasized general strengthening, flexibility, balance, and functional training without a specific focus on eccentric quadriceps loading. Warm-up activities included light aerobic exercises and general lower limb stretching. The main exercise component consisted of concentric quadriceps and hamstring strengthening exercises, straight leg raises, closed kinetic chain exercises, balance training, and proprioceptive exercises as per standard clinical rehabilitation guidelines. Exercise intensity was maintained at low to moderate levels and progressed gradually based on the participant’s recovery and functional ability. Cool-down exercises included static stretching of the lower limb muscles. Similar to the experimental group, all sessions were supervised by a qualified physiotherapist, and participants were monitored for any adverse effects during the intervention period.
Both groups followed identical session frequency and duration to ensure uniformity, with the only difference being the inclusion of cross eccentric quadriceps strength training in the experimental group. This approach allowed for a clear comparison of outcomes related to functional disability, quadriceps strength, and knee function between the two groups. |
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
25.00 Year(s) |
| Gender |
Both |
| Details |
COLLEGIATE FOOTBALL PLAYERS WHO HAVE UNDERGONE ACL RECONSTRUCTION SURGERY
MALE AND FEMALE PLAYERS AGED BETWEEN 18 TO 25 YEARS
PLAYERS WHO HAVE COMPLETED THE REHABILITATION PHASE AND IN THE STRENGTH TRAINING PHASE
PLAYERS WHO HAVE COMPLETED AT LEAST SIX MONTHS POST SURGERY
PLAYERS WHO HAVE NO OTHER KNEE INJURIES OR PREVIOUS KNEE SURGERIES |
|
| ExclusionCriteria |
| Details |
PLAYERS WHO HAVE NOT COMPLETED THE REHABILITATION PHASE AND ARE NOT IN THE STRENGTH TRAINING PHASE
PLAYERS WHO HAVE A HISTORY OF OTHER LOWER LIMB INJURIES THAT MAY AFFECT THEIR ABILITY TO PARTICIPATE IN THE STUDY
PLAYERS WHO HAVE ANY PRE EXISTING MEDICAL CONDITION THAT MAY INTERFERE WITH THE STUDY RESULTS
PLAYERS WHO HAVE UNDERGONE ANY OTHER SURGICAL PROCEDURES ON THE KNEE JOINT
PLAYERS WHO ARE CURRENTLY UNDERGOING REHABILITATION FOR ANY OTHER INJURIES |
|
|
Method of Generating Random Sequence
|
Computer generated randomization |
|
Method of Concealment
|
Sequentially numbered, sealed, opaque envelopes |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
| KNEE INJURY AND OSTEOARTHITIS OUTCOME SCORE (KOOS) |
BASELINE SIX WEEKS AND AT TWELEVETH WEEKS |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| INTERNATIONAL KNEE DOCUTMENTATION COMMITTEE SUBJECTIVE KNEE EVALUATION FORM (IKDC) |
BASELINE SIX WEEKS AND AT TWELVETH WEEKS |
|
|
Target Sample Size
|
Total Sample Size="40"
Sample Size from India="40"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
05/02/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="0"
Months="6"
Days="10" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
This randomized controlled study aims to evaluate the effectiveness of cross eccentric quadriceps strength training compared to standard rehabilitation in improving functional disability and quadriceps strength among collegiate football players who have undergone anterior cruciate ligament (ACL) reconstruction. A total of 60 participants meeting the inclusion criteria will be recruited and randomly allocated into two groups: an experimental group receiving cross eccentric quadriceps strengthening and a control group receiving conventional rehabilitation.
Baseline assessments will be conducted after obtaining informed consent, measuring functional disability using the Knee Injury and Osteoarthritis Outcome Score (KOOS) and the International Knee Documentation Committee (IKDC) subjective knee evaluation form, along with isometric quadriceps strength using a dynamometer. The intervention will be administered over a 12-week period, with follow-up assessments performed at 6 weeks and 12 weeks by blinded assessors.
The primary outcome measure will be functional disability, while isometric quadriceps strength will serve as a secondary outcome. Data will be analyzed using appropriate parametric or non-parametric statistical tests based on data distribution, with normality assessed using the Shapiro–Wilk or Kolmogorov–Smirnov tests. Ethical approval will be obtained prior to study commencement, and the study will adhere to the principles of the Declaration of Helsinki. The findings are expected to provide evidence-based guidance for optimizing rehabilitation protocols in athletes following ACL reconstruction. |