| CTRI Number |
CTRI/2026/04/108369 [Registered on: 15/04/2026] Trial Registered Prospectively |
| Last Modified On: |
13/04/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Ayurveda |
| Study Design |
Randomized, Parallel Group, Active Controlled Trial |
|
Public Title of Study
|
Efficacy of Murivenna Taila Bandage and Paraffin Wax Application in Post-Traumatic Stiffness in Distal End Radius Fracture |
|
Scientific Title of Study
|
A Clinical Study to Evaluate the Efficacy of Murivenna Taila Bandage and Paraffin Wax Application in Post-Traumatic Stiffness in Distal End Radius Fracture |
| Trial Acronym |
|
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
ProfANIL KUMAR SHARMA |
| Designation |
Professor |
| Affiliation |
R.G.G.P.G.Ayurvedic College and hospital Paprola |
| Address |
Room no. 206 of Shalya tantra Department anatomy block R.G.G.P.G. AYURVEDIC COLLEGE AND HOSPITAL PAPROLA 176115 KANGRA
Himachal Pradesh
Kangra
HIMACHAL PRADESH
176115
India |
| Phone |
9805056393 |
| Fax |
|
| Email |
dranilpaprola@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
ProfANIL KUMAR SHARMA |
| Designation |
Professor |
| Affiliation |
R.G.G.P.G.Ayurvedic College and hospital Paprola |
| Address |
Room no. 206 of Shalya tantra Department anatomy block R.G.G.P.G. AYURVEDIC COLLEGE AND HOSPITAL PAPROLA 176115 KANGRA
Himachal Pradesh
Kangra
HIMACHAL PRADESH
176115
India |
| Phone |
9805056393 |
| Fax |
|
| Email |
dranilpaprola@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
DrAvinash kumar |
| Designation |
PG Scholar |
| Affiliation |
R.G.G.P.G. AYURVEDIC COLLEGE AND HOSPITAL PAPROLA |
| Address |
R.G.G.P.G. AYURVEDIC COLLEGE AND HOSPITAL PAPROLA 176115 KANGRA
Himachal Pradesh
Kangra
HIMACHAL PRADESH
176115
India |
| Phone |
7018973638 |
| Fax |
|
| Email |
dravinashkumar16@gmail.com |
|
|
Source of Monetary or Material Support
|
| Vaidyaratnam Oushadhasala Pvt. Ltd.
Vaidyaratnam Road, ThaikkattusseryP.O.,
Ollur, Thrissur – 680306,
Kerala, India
,
R.G.G. P.G AYURVEDIC COLLEGE AND HOSPITAL, PAPROLA,KANGRA (H.P.) in Shalya tantra OPD /IPD |
|
|
Primary Sponsor
|
| Name |
Principal RGGPG Ayurvedic College and hospital paprola |
| Address |
Rajiv Gandhi Govt.Post Graduate Ayurvedic college and hospital Paprola Teh. Baijnath Distt. Kangra Himachal Pradesh 176115 |
| Type of Sponsor |
Government medical college |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Prof Anil Kumar Sharma |
R.G.G.P.G. AYURVEDIC COLLEGE AND HOSPITAL PAPROLA 176115 KANGRA Himachal Pradesh |
OPD / IPD OF SHALYA TANTRA DEPARTMENT OF R.G.G.P.G. AYURVEDIC COLLEGE AND HOSPITAL PAPROLA 176115 KANGRA
Himachal Pradesh
Kangra
HIMACHAL PRADESH |
9805056393
dranilpaprola@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| INSTITUTIONAL ETHICAL COMMITTEE (HUMAN) |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition:M256||Stiffness of joint, not elsewhereclassified. Ayurveda Condition: STAMBAHÂ (KEVALAVATA), |
|
|
Intervention / Comparator Agent
|
| sno | Intervention/Comparator | Type | Drug-Type | Procedure Name | Details | | 1 | Intervention Arm | Procedure | - | Murivenna Tail Bandage | (Procedure Reference: susruta samhita bhagna chikitsa, Procedure details: Lukewarm Murivenna Taila will be applied over the wrist joint. Then, a
4-inch cotton bandage soaked in lukewarm Murivenna Taila, and five layers of cotton bandage will be applied over the affected wrist joint, followed by covering with a plastic sheet/plastic glove for 20 minutes. This will be followed by rehabilitation exercises.
Duration: Once daily for 15 days.
Exercises will be advised to perform three times daily.)
| | 2 | Comparator Arm (Non Ayurveda) | | - | Paraffin wax application | Five coats of paraffin wax will be applied to the affected wrist joint, followed by covering with the plastic sheet/plastic glove for 20 minutes. This will be followed by rehabilitation exercises.
Duration: Once daily for 15 days.
Exercises will be advised to perform three times daily. |
|
|
|
Inclusion Criteria
|
| Age From |
40.00 Year(s) |
| Age To |
70.00 Year(s) |
| Gender |
Both |
| Details |
Patient having Post -Traumatic Stiffness in Distal End Radius Fracture.
Patient willing to participate in trail.
Patient of age group 40-70 years of either gender. |
|
| ExclusionCriteria |
| Details |
Patients not willing for trail.
Patients having pre-existing wrist deformities.
Patients having rheumatoid arthritis,gouty arthritis. |
|
|
Method of Generating Random Sequence
|
Other |
|
Method of Concealment
|
Other |
|
Blinding/Masking
|
Open Label |
|
Primary Outcome
|
| Outcome |
TimePoints |
| Improvement in wrist ROM ,Reduction in pain |
Day 0,7th day ,15th day and follow-up on 22 day |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| Reduction in tenderness & overall clinical improvement |
Day 0 ,Day 7th, & Day 15th & follow up on 22 day |
|
|
Target Sample Size
|
Total Sample Size="30"
Sample Size from India="30"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
Phase 2 |
|
Date of First Enrollment (India)
|
24/04/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="0"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Post-traumatic stiffness is a common complication following distal end radius fractures and leads to pain, restricted wrist movement, and functional impairment. Effective rehabilitation is essential to restore joint mobility and function. In Ayurveda, management of fractures (Bhagna) includes various therapeutic measures such as bandaging and rehabilitative exercises. Murivenna Taila, an Ayurvedic formulation mentioned in the Ayurvedic Formulary of India, is traditionally used for external application in trauma-related conditions. Paraffin wax therapy, a physiotherapy modality, provides deep heat that helps reduce pain and stiffness and improves joint mobility. This randomized controlled clinical study aims to evaluate and compare the efficacy of Murivenna Taila bandage and paraffin wax therapy in patients with post-traumatic stiffness following distal end radius fracture. A total of 30 patients will be randomly divided into two groups of 15 each. One group will receive paraffin wax therapy, while the other will receive Murivenna Taila bandage application for 15 days along with rehabilitation exercises. The outcomes will be assessed using pain score, tenderness, and wrist range of motion measured by goniometer. The study aims to generate clinical evidence regarding the effectiveness of Murivenna Taila bandage in improving wrist mobility and reducing post-traumatic stiffness. |