| CTRI Number |
CTRI/2026/04/107473 [Registered on: 02/04/2026] Trial Registered Prospectively |
| Last Modified On: |
02/04/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Observational |
|
Type of Study
|
Cross Sectional Study |
| Study Design |
Other |
|
Public Title of Study
|
The Effect of Age on Skin Elasticity and Moisture Levels |
|
Scientific Title of Study
|
Co-relation of age with elasticity and hydration of skin -A CROSS SECTIONAL STUDY |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
DR SUDHIR KUMAR |
| Designation |
ASSOCIATE PROFESSOR |
| Affiliation |
Ch. Brahm Prakash Ayurved Charak Sansthan |
| Address |
Room no.326 3rd floor, Institute Block, Ch. Brahm Prakash Ayurved Charak Sansthan, Khera Dabar, Najafgarh, Delhi-110073
Room no.326 3rd floor, Institute Block, Ch. Brahm Prakash Ayurved Charak Sansthan, Khera Dabar, Najafgarh, Delhi-110073
South West
DELHI
110073
India |
| Phone |
9718287772 |
| Fax |
|
| Email |
namdv.mayur007@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
MAYUR |
| Designation |
POST GRADUATE |
| Affiliation |
Ch. Brahm Prakash Ayurved Charak Sansthan Najafgarh |
| Address |
Ch. Brahm Prakash Ayurved Charak Sansthan Najafgarh
Room no.322 3rd floor, Institute Block, Ch. Brahm Prakash Ayurved Charak Sansthan, Khera Dabar, Najafgarh, Delhi-110073
South West
DELHI
110073
India |
| Phone |
08076682174 |
| Fax |
|
| Email |
namdv.mayur007@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
MAYUR |
| Designation |
POST GRADUATE |
| Affiliation |
Ch. Brahm Prakash Ayurved Charak Sansthan Najafgarh |
| Address |
Ch. Brahm Prakash Ayurved Charak Sansthan Najafgarh
Room no.322 3rd floor, Institute Block, Ch. Brahm Prakash Ayurved Charak Sansthan, Khera Dabar, Najafgarh, Delhi-110073
South West
DELHI
110073
India |
| Phone |
08076682174 |
| Fax |
|
| Email |
namdv.mayur007@gmail.com |
|
|
Source of Monetary or Material Support
|
| OPD OF ALL INDIA INSTITUTEBOF AYURVEDA, NEW DELHI |
|
|
Primary Sponsor
|
| Name |
CH. BRAHM PRAKASH AYURVED CHARAK SANSTHAN |
| Address |
CH. BRAHM PRAKASH AYURVED CHARAK SANSTHAN, KHERA DABAR, NAJAFGARH,NEW DELHI-110073 |
| Type of Sponsor |
Government medical college |
|
|
Details of Secondary Sponsor
|
| Name |
Address |
| Ch Brahm Prakash Ayurved Charak Sansthan |
CH. BRAHM PRAKASH AYURVED CHARAK SANSTHAN, KHERA DABAR, NAJAFGARH,NEW DELHI-110073 |
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| MAYUR |
Ch.Brahm Prakash Ayurved Charak Sansthan |
Ch. Brahm Prakash Ayurved Charak Sansthan Najafgarh
South West
DELHI |
08076682174
namdv.mayur007@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional Ethical Committee |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Healthy Human Volunteers |
Age related changes in skin health. |
|
|
Intervention / Comparator Agent
|
| sno | Intervention/Comparator | Type | Drug-Type | Procedure Name | Details |
|
| Intervention |
Nil |
Nil |
| Intervention |
Nil |
Nil |
| Intervention |
Nil |
Nil |
| Intervention |
Nil |
Nil |
|
|
Inclusion Criteria
|
| Age From |
10.00 Year(s) |
| Age To |
70.00 Year(s) |
| Gender |
Both |
| Details |
1.Willing to participate and agree to provide written informed consent.
2.Healthy participants of all age groups between 10 years to 70 years will be enrolled at AIIA.
3.No use of anti-inflammatory drugs on the test area in the past three months and no laser treatment in the past three months.
4.No participation in other clinical trials in the past three months.
5.Skin in the test area must be free of scars, birthmarks, atrophy, or other conditions that could affect the test results
|
|
| ExclusionCriteria |
| Details |
1.Use of antihistamine in the past week or immune-suppressants in the past month.
2.Currently undergoing facial treatment or use of products to improve facial skin condition in the past month
3.Presence of untreated inflammatory skin diseases
4.Insulin-dependent diabetes
5.History of cancer chemotherapy in the past six months
6.Immune deficiencies or autoimmune disease
7.Participation in other clinical trials
8.Pregnant and lactating women
|
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
1.This work will lead to development of literature in Ayurveda Pramana Sharir.
2.This research work will be a step towards inclusion of standardized parameters (Guruvadi Guna) of various biophysical components (Dhatus etc) of the body which can be used for further clinical studies in Ayurveda.
3.This research work can be used as a stepping stone towards studies on biological aging through Ayurveda parameter
|
1.This work will lead to development of literature in Ayurveda Pramana Sharir.
2.This research work will be a step towards inclusion of standardized parameters (Guruvadi Guna) of various biophysical components (Dhatus etc) of the body which can be used for further clinical studies in Ayurveda.
3.This research work can be used as a stepping stone towards studies on biological aging through Ayurveda parameter
|
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| NIL |
NIL |
|
|
Target Sample Size
|
Total Sample Size="80"
Sample Size from India="80"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
20/04/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="0"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Yet Recruiting |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Co-relation of age with the elasticity and hydration of skin - A cross-sectional study. This cross-sectional observational study investigates the relationship between chronological age and biophysical skin parameters (elasticity via Cutometer and hydration via Delfin MoistureMeter) in 80 healthy participants aged 10-70 years. Conducted at Ch. Brahm Prakash Ayurved Charak Sansthan, New Delhi, and All India Institute of Ayurveda, it aims to quantify Guruvadi Guna equivalents like Sthira (elasticity) and Snigdha (hydration) for Ayurvedic Pramana Sharir assessment. Hypothesis: There is an associationof age with hydration & elasticity of skin
Primary objective: Measure skin elasticity/hydration; secondary: Correlate with age groups using Pearson/Spearman tests post-Shapiro-Wilk normality check. Inclusion: Healthy volunteers with consent; exclusions: Skin conditions, recent medications, pregnancy. Expected outcomes include norms for biological aging markers in Ayurveda, bridging classical texts with modern biophysics. |