| CTRI Number |
CTRI/2026/02/103730 [Registered on: 12/02/2026] Trial Registered Prospectively |
| Last Modified On: |
12/02/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Dentistry |
| Study Design |
Randomized, Parallel Group, Multiple Arm Trial |
|
Public Title of Study
|
Evaluation of different graft materials in gum repositioning surgery for the treatment of multiple gum recession in upper teeth |
|
Scientific Title of Study
|
Comparative evaluation of Acellular Dermal matrix, Titanium Platelet Rich Fibrin and Connective Tissue Graft using Zucchellis modification of Coronally
Advanced Flap technique in the management of multiple adjacent Cairo’s RT1 Marginal
Tissue Recession in maxilla: A Randomized Clinical Trial |
| Trial Acronym |
|
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
NANEPALLI SAI TEJA |
| Designation |
Resident |
| Affiliation |
Army Dental Centre Research and Referral |
| Address |
Department of Periodontology
Army Dental Centre (Research and Referral)
Delhi Cantt
New Delhi
DELHI
110010
India |
| Phone |
7036876341 |
| Fax |
|
| Email |
saiteja6279@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr(Col) T Prasanth |
| Designation |
Head of Department |
| Affiliation |
Army Dental Centre Research and Referral |
| Address |
Department of Periodontology
Army Dental Centre (Research and Referral)
Delhi Cantt
New Delhi
DELHI
110010
India |
| Phone |
8284851155 |
| Fax |
|
| Email |
tprasanthavin@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
NANEPALLI SAI TEJA |
| Designation |
Resident |
| Affiliation |
Army Dental Centre Research and Referral |
| Address |
Department of Periodontology
Army Dental Centre (Research and Referral)
Delhi Cantt
New Delhi
DELHI
110010
India |
| Phone |
7036876341 |
| Fax |
|
| Email |
saiteja6279@gmail.com |
|
|
Source of Monetary or Material Support
|
| Army Dental Centre (Research & Referral)
Delhi Cantt-110010 |
|
|
Primary Sponsor
|
| Name |
Army Dental Centre (Research and Referral) Delhi Cantt |
| Address |
Army Dental Centre (Research & Referral)
Delhi Cantt-110010 |
| Type of Sponsor |
Research institution and hospital |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr NANEPALLI SAI TEJA |
Army Dental Centre (Research and Referral) |
Department of Periodontology/ 1C Wing/ Room no 209
New Delhi
DELHI |
7036876341
saiteja6279@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Army dental centre R and R |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: K060||Gingival recession, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Intervention |
Acellular Dermal matrix |
Comparative evaluation of Acellular Dermal matrix, Titanium Platelet Rich Fibrin and Connective Tissue Graft using Zucchellis modification of Coronally Advanced Flap technique in the management of multiple adjacent Cairo’s RT1 Marginal Tissue Recession in maxilla |
| Comparator Agent |
Connective Tissue Graft |
Comparative evaluation of Acellular Dermal matrix, Titanium Platelet Rich Fibrin and Connective Tissue Graft using Zucchellis modification of Coronally Advanced Flap technique in the management of multiple adjacent Cairo’s RT1 Marginal Tissue Recession in maxilla |
| Intervention |
Titanium Platelet Rich Fibrin |
Comparative evaluation of Acellular Dermal matrix, Titanium Platelet Rich Fibrin and Connective Tissue Graft using Zucchellis modification of Coronally Advanced Flap technique in the management of multiple adjacent Cairo’s RT1 Marginal Tissue Recession in maxilla |
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
50.00 Year(s) |
| Gender |
Both |
| Details |
1.Patients with ASA-1 Physical Status Classification
2. Multiple adjacent Cairo’s RT1 MTR on maxillary anterior teeth or premolars
3. Intact papilla on the mesial and distal aspect of the involved tooth
4. No surgical periodontal therapy in last 1 year on the involved site |
|
| ExclusionCriteria |
| Details |
1. Smokers and chewers of tobacco
2. Teeth with mobility or root caries
3. Non Carious Cervical Lesions (NCCL)
4. Pregnant and lactating women
5. Malposed teeth
6. Systemically compromised patients |
|
|
Method of Generating Random Sequence
|
Coin toss, Lottery, toss of dice, shuffling cards etc |
|
Method of Concealment
|
Sequentially numbered, sealed, opaque envelopes |
|
Blinding/Masking
|
Participant and Outcome Assessor Blinded |
|
Primary Outcome
|
| Outcome |
TimePoints |
Complete Root Coverage (CRC)
|
Baseline, 3 months, 6 months
|
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
1. Gingival Recession Height (RH)
2. Recession Width (RW)
3. Mean Root Coverage (MRC)
4. Width of Keratinized Gingiva (WKG)
5. Clinical Attachment Level (CAL) |
Baseline, 3 months, 6 months |
|
|
Target Sample Size
|
Total Sample Size="21"
Sample Size from India="21"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
27/02/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="6"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Yet Recruiting |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
In this study iam comparing percentage of root coverage that could be achieved by using coronally advanced flap technique with Acellular dermal matrix , Titanium platelet rich fibrin and connective tissue graft which is considered as gold standard till now. Patients will be enrolled based on inclusion and exclusion criteria.Procedures will be carried under aseptic conditions.All the measurements will be taken at baseline, 3 months, 6 months post operatively and will be subjected to statistical analysis. |