1. What data in particular will be shared?
   Response - All of the individual participant data collected during the trial, after de-identification.
   


2. What additional supporting information will be shared?
   Response -  Study Protocol
   Response -  Statistical Analysis Plan
   Response - Clinical Study Report
   
   
3. Who will be able to view these files?
   Response - Anyone
   


4. For what types of analyses will this data be available?
   Response - Any purpose.
   


5. By what mechanism will data be made available?
   Response (Others) -  Nil


6. For how long will this data be available start date provided 17-07-2027 and end date provided 17-07-2031?
   Response - Beginning 3 months and ending 5 years following article publication.
   


7. Any URL or additional information regarding plan/policy for sharing IPD? 
   Additional Information - Nil

In paediatric anesthesia, a notable challenge arises from the lack of personalized mechanical ventilation strategies tailored to individual respiratory capacities during laparoscopic surgeries. Current practice often employs fixed tidal volume (Vt) approaches, which may not effectively account for variations in lung function among paediatric patients. Consequently, this one-size-fits-all approach increases the risk of intraoperative lung injury, morphological alterations, and postoperative pulmonary complications (PPCs). Addressing this gap in ventilation management is crucial to optimize perioperative care and improve outcomes in paediatric laparoscopic surgery.

Novelty: This research lies in its personalized mechanical ventilation strategy, utilizing gold standard spirometry to individualize tidal volume for each patient. This approach contrasts with current practices and could significantly contribute to our understanding of mechanical ventilation in pediatric laparoscopic surgery, potentially improving outcomes.

Methods: The study will randomize pediatric patients into two groups: one receiving low tidal volume ventilation (Group L) and the other guided by preoperative spirometry (Group S). Anesthesia maintenance will utilize the Mindray Wato Ex55 ventilator, with double-blinding to ensure unbiased assessment. 

Objectives include evaluating the impact of spirometry-measured tidal volume on intra-operative lung atelectasis, postoperative FEV1/FVC, Modified Aldrete’s score, and pulmonary complications. Expected outcomes: Include improvements in intra-operative lung function, postoperative respiratory parameters, recovery scores, and a reduction in pulmonary complications. 

In summary, this research offers a tailored approach to mechanical ventilation in pediatric laparoscopic surgery, aiming to improve perioperative care and outcomes through innovative use of preoperative spirometry-measured tidal volume.