| CTRI Number |
CTRI/2026/02/102764 [Registered on: 02/02/2026] Trial Registered Prospectively |
| Last Modified On: |
02/02/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Surgical/Anesthesia |
| Study Design |
Randomized, Parallel Group, Active Controlled Trial |
|
Public Title of Study
|
Comparison of two ramped positioning techniques for improving intubation in obese patients |
|
Scientific Title of Study
|
Comparison of the Efficacy of Modified Universal RAMP vs Inflatable RAMP for Intubation with conventional laryngoscopy in Obese Patients Undergoing Elective Surgeries. |
| Trial Acronym |
Nil |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| Nil |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
PRIYANKA REDDYBATHULA |
| Designation |
Postgraduate MD Anaesthesiology |
| Affiliation |
SAVEETHA INSTITUTE OF MEDICAL AND TECHNICAL SCIENCES |
| Address |
Department of Anaesthesiology, 2nd floor,Saveetha Medical College and Hospital, Saveetha nagar thandalam,chennai NH48,tamilnadu 602105
Saveetha nagar, thandalam,Chennai NH48,Tamilnadu 602105
Kancheepuram
TAMIL NADU
602106
India |
| Phone |
8885224530 |
| Fax |
|
| Email |
priyankareddy.3331@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr RAJKUMARAN |
| Designation |
Assistant Professor MD Anaesthesiology |
| Affiliation |
Saveetha Institute of Medical and Technical Sciences |
| Address |
Department of Anaesthesiology, 2nd floor,Saveetha Medical College and Hospital, Saveetha nagar thandalam,chennai NH48,tamilnadu 602105
Department of Anaesthesiology, 2nd floor,Saveetha nagar, thandalam,Chennai NH48,Tamilnadu 602105
Kancheepuram
TAMIL NADU
602105
India |
| Phone |
9500032332 |
| Fax |
|
| Email |
rajkumarankamaraj@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Dr RAJKUMARAN |
| Designation |
Assistant Professor MD Anaesthesiology |
| Affiliation |
Saveetha Institute of Medical and Technical Sciences |
| Address |
Department of Anaesthesiology, 2nd floor,Saveetha Medical College and Hospital, Saveetha nagar thandalam,chennai NH48,tamilnadu 602105
Saveetha nagar thandalam,chennai NH48,tamilnadu 602105
Kancheepuram
TAMIL NADU
602105
India |
| Phone |
9500032332 |
| Fax |
|
| Email |
rajkumarankamaraj@gmail.com |
|
|
Source of Monetary or Material Support
|
| Department of Anaesthesiology, 2nd floor,Saveetha Institute of Medical and Technical Sciences , saveetha nagar ,thandalam, chennai NH48. 6,kanchipuram, tamilnadu,india.602105. |
|
|
Primary Sponsor
|
| Name |
Saveetha Institute of Medical and Technical Sciences |
| Address |
Saveetha nagar, thandalam,Chennai NH48,Tamilnadu 602105 |
| Type of Sponsor |
Research institution and hospital |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Priyanka reddybathula |
Saveetha Institute of Medical and Technical Sciences |
Department of Anaesthesiology, 2nd floor,Saveetha medical college and hospital, Saveetha nagar, thandalam,Chennai NH48,Tamilnadu 602105 india
Kancheepuram
TAMIL NADU |
8885224530
priyankareddy.3331@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Saveetha medical college and hospital institutional ethics committee |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: E669||Obesity, unspecified, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Comparator Agent |
RAMP positioning for tracheal intubation in obese patients using inflatable ramp |
Eligible obese patients will be randomized to receive airway positioning using inflatable RAMP to achieve alignment of the external auditory meatus with the sternal notch.following positioning , standard anesthetic induction and tracheal intubation using conventional direct laryngoscopy will be performed in both groups.duration of 1 to 2 minutes. |
| Intervention |
RAMP positioning for tracheal intubation in obese patients using modified universal RAMP |
Eligible obese patients will be randomized to receive airway positioning using Modified Universal RAMP will be placed under the head, neck, shoulders, and upper torso to achieve alignment of the external auditory meatus with the sternal notch.. Following positioning, standard anesthetic induction and tracheal intubation using conventional direct laryngoscopy will be performed in both groups.intevenrion duration 1 to 2 minutes |
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
60.00 Year(s) |
| Gender |
Both |
| Details |
BMI more than 30kg per m2
ASA classification 1 and 2
Both gender
Elective Surgeries under GA
|
|
| ExclusionCriteria |
| Details |
Hb less than 8 g percentage
Hemodynamically unstable systolic blood pressure less than 90 mmhg on innotrope support
Coronary artery disease.
|
|
|
Method of Generating Random Sequence
|
Random Number Table |
|
Method of Concealment
|
Sequentially numbered, sealed, opaque envelopes |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
To compare the efficacy of the Modified Universal RAMP and Inflatable RAMP in obese patients undergoing elective surgeries by evaluating the ease of laryngoscopy, quality of glottic visualization, and overall intubation success using conventional laryngoscope
|
Immediately after positioning, during laryngoscopy, and at completion of tracheal intubation. |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| Intubation time |
Immediately after positioning, during laryngoscopy, and at completion of tracheal intubation. |
|
|
Target Sample Size
|
Total Sample Size="60"
Sample Size from India="60"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
Phase 2/ Phase 3 |
|
Date of First Enrollment (India)
|
13/02/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
13/02/2026 |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="0"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Yet Recruiting |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Obese patients present significant challenges during airway management due to altered airway anatomy and reduced functional residual capacity, increasing the risk of difficult laryngoscopy and failed intubation. Ramped positioning improves airway alignment and oxygenation; however, the optimal ramping technique remains uncertain. The MURAMP Trial is a prospective, randomized, active-controlled, parallel-group study designed to compare Modified Universal RAMP and Inflatable RAMP positioning for tracheal intubation using conventional direct laryngoscopy in obese patients undergoing elective surgery. The study aims to evaluate ease of laryngoscopy, quality of glottic visualization, and first-pass intubation success between the two techniques, in order to identify the more effective ramping method for airway optimization in obese population |