| CTRI Number |
CTRI/2026/02/104296 [Registered on: 19/02/2026] Trial Registered Prospectively |
| Last Modified On: |
19/02/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Homeopathy |
| Study Design |
Randomized, Parallel Group, Placebo Controlled Trial |
|
Public Title of Study
|
To study the effect of homoeopathic medicine treatment of post traumatic stress disorder from 15 to 40 years of age |
|
Scientific Title of Study
|
the Effectiveness of Homoeopathic medicines in the treatment of Post Traumatic Stress Disorder from 15 to 40 years of age. |
| Trial Acronym |
Nil |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
RADHIKA |
| Designation |
PG SCHOLAR |
| Affiliation |
Sri Ganganagar Homoeopathic Medical College Hospital and Research Institute |
| Address |
Department of psychiatry Ground floor PG Block Near RIICO Bus Stop Hanumangargh Road Ganganagar Rajasthan
India
Near Ricco Bus Stand Hanumangarh Road Sri Ganganagar
Ganganagar
Rajasthan
335002
INDIA
Ganganagar
RAJASTHAN
335002
India |
| Phone |
9872552169 |
| Fax |
|
| Email |
makkarradhika94@gmail,com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Nalini |
| Designation |
Assiistant Professor Dept of psychiatry |
| Affiliation |
Sri Ganganagar Homoeopathic Medical College Hospital and Research Institute |
| Address |
Department of psychiatry Ground floor PG Block Near RIICO Bus Stop Hanumangargh Road Ganganagar Rajasthan
India
Ganganagar
RAJASTHAN
335002
India |
| Phone |
9782300599 |
| Fax |
|
| Email |
drnalini12@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Radhika |
| Designation |
PG SCHOLAR |
| Affiliation |
Sri Ganganagar Homoeopathic Medical College Hospital and Research Institute |
| Address |
Department of psychiatry Ground floor PG Block Near RIICO Bus Stop Hanumangargh Road Ganganagar Rajasthan
India
Ganganagar
RAJASTHAN
335002
India |
| Phone |
9872552169 |
| Fax |
|
| Email |
makkarradhika94@gmail,com |
|
|
Source of Monetary or Material Support
|
| Sri Ganganagar Homeopathic Medical
college Hospital and Research Institute, Sriganganagar Rajasthan 335002 India |
|
|
Primary Sponsor
|
| Name |
Tantia university |
| Address |
SRI GANGANAGAR HOMOEOPATHIC MEDICAL COLLEGE HOSPITAL AND RESEARCH INSTITUTE, Rajasthan 335002 India department -Psychiatry |
| Type of Sponsor |
Private medical college |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 2 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Radhika |
Sri Ganganagar Homoeopathic Medical college Hospital and Research Institute |
Sri Ganganagar Homoeopathic Medical college Hospital and Research Institute Rajasthan 335002 India department -Psychiatry
Ganganagar
RAJASTHAN |
9872552169
makkarradhika94@gmail.com |
| Radhika |
Sri Ganganagar Homoeopathic Medical college Hospital and Research Institute, Sri Ganganagar |
Sri Ganganagar Homoeopathic Medical college Hospital and Research Institute Rajasthan 335002 India department -Psychiatry
Ganganagar
RAJASTHAN |
9872552169
makkarradhika94@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Sunil Bishnoi |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: F431||Post-traumatic stress disorder (PTSD), |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Intervention |
Individualized homeopathic treatment |
Dose and vitality may vary according to susceptibility and sensitivity of patient,acute and chronic nature of disease .In this trail dosage repetition and dispensery will be as per need of case and guidelines of organon of medicine Reassessment will be done after 3 months Ist done at time of first prescription, after casetaking Then on subsequent follow ups Oral route of administration |
| Comparator Agent |
Placebo |
1 dose after case taking, on subsequent follow ups , or reassessment after 3 month,mode of adminstration -oral |
|
|
Inclusion Criteria
|
| Age From |
15.00 Year(s) |
| Age To |
40.00 Year(s) |
| Gender |
Both |
| Details |
1.Diagnosed cases of PTSD age group 15 to 40years according to DSM-5 Criteria
2.Willingness for written consent for research study |
|
| ExclusionCriteria |
| Details |
Patient with severe depression
Use of physcotropic medicines during study
Consent not given |
|
|
Method of Generating Random Sequence
|
Coin toss, Lottery, toss of dice, shuffling cards etc |
|
Method of Concealment
|
Sequentially numbered, sealed, opaque envelopes |
|
Blinding/Masking
|
Participant and Outcome Assessor Blinded |
|
Primary Outcome
|
| Outcome |
TimePoints |
| Reduction in stress level within 4 weeks |
Comparative effectiveness to identify statistical significance between two groups |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| Nil |
Nil |
|
|
Target Sample Size
|
Total Sample Size="100"
Sample Size from India="100"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
10/03/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="0"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Post-Traumatic Stress Disorder (PTSD) is a psychiatric condition triggered by exposure to traumatic events such as war, natural disasters, sexual assault, or serious accidents. The condition can severely impair cognitive, emotional, and social functioning if not managed effectively. This paper reviews the core symptoms, biological mechanisms, risk factors, and the effectiveness of therapeutic interventions like Cognitive Behavioral Therapy (CBT), Eye Movement Desensitization and Reprocessing (EMDR), and pharmacological treatments. |