| CTRI Number |
CTRI/2026/01/100787 [Registered on: 09/01/2026] Trial Registered Prospectively |
| Last Modified On: |
09/01/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Homeopathy |
| Study Design |
Single Arm Study |
|
Public Title of Study
|
To study on the Effect of Homeopathic Medicines in the Treatment of High Uric Acid Levels in People of all age groups. |
|
Scientific Title of Study
|
Effectiveness of Individualized Homeopathic Medicine in management of Hyperuricemia in all the age group - A Prospective case series |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Aditi Bhanudas Bhise |
| Designation |
MD Scholar |
| Affiliation |
Motiwala National Homoeopathic Medical College and Hospital, Nashik |
| Address |
Department of Practice of Medicine, Motiwala National Homoeopathic Medical College and Hospital, Dhruv Nagar, Satpur Colony, Nashik
Nashik
MAHARASHTRA
422012
India |
| Phone |
8379045929 |
| Fax |
|
| Email |
adi.bhise2969@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Ajay Balchandra Valke |
| Designation |
Professor |
| Affiliation |
Motiwala National Homoeopathic Medical College and Hospital, Nashik |
| Address |
Department of Practice of Medicine, Motiwala National Homoeopathic Medical College and Hospital, Dhruv Nagar, Satpur Colony, Nashik
Nashik
MAHARASHTRA
422012
India |
| Phone |
9326805031 |
| Fax |
|
| Email |
drvalkeajay1972@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Dr Ajay Balchandra Valke |
| Designation |
Professor |
| Affiliation |
Motiwala National Homoeopathic Medical College and Hospital, Nashik |
| Address |
Department of Practice of Medicine, Motiwala National Homoeopathic Medical College and Hospital, Dhruv Nagar, Satpur Colony, Nashik
Nashik
MAHARASHTRA
422012
India |
| Phone |
9326805031 |
| Fax |
|
| Email |
drvalkeajay1972@gmail.com |
|
|
Source of Monetary or Material Support
|
| Motiwala National Homoeopathic Medical College and Hospital, Dhurav Nagar, Satpur Colony, Nashik, Maharashtra, India 422012 |
|
|
Primary Sponsor
|
| Name |
Dr Aditi Bhanudas Bhise |
| Address |
Motiwala National Homoeopathic Medical College and Hospital, Dhurav Nagar, Satpur Colony, Nashik, Maharashtra, India 422012 |
| Type of Sponsor |
Other [Self] |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Aditi Bhanudas Bhise |
Motiwala National Homoeopathic Medical College and Hospital, Nashik |
Department of Practice of Medicine, Motiwala National Homoeopathic Medical College and Hospital, Dhruv Nagar, Satpur Colony, Nashik
Nashik
MAHARASHTRA |
8379045929
adi.bhise2969@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional Ethical Cell Motiwala Homoeopathic Medical College |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: E790||Hyperuricemia without signs of inflammatory arthritis and tophaceous disease, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Intervention |
Individualized Homoeopathic Medicine |
Individualized homoeopathic treatment will be given to participants with hyperuricemia based on detailed case taking in accordance with homoeopathic principles. Selection of medicine, potency, and repetition will be decided individually. Medicines will be administered for a total duration of 6 months. Regular follow-ups will be conducted during the study period to assess clinical improvement and changes in serum uric acid levels. Standard lifestyle and dietary advice will be given to all participants. |
| Comparator Agent |
Nil |
Nil |
|
|
Inclusion Criteria
|
| Age From |
20.00 Year(s) |
| Age To |
80.00 Year(s) |
| Gender |
Both |
| Details |
1. Patient having uric acid from 5.7 mg/dl in females and 7 mg/dl in males till 10 mg/dl in both the sexes.
2. Symptomatic patient of hyperuricemia with smaller joint pain.
3. Patient who give consent to the study. |
|
| ExclusionCriteria |
| Details |
1. Patient not willing to give consent
2. Patient having uric acid more than 10mg/dl.
3. Patient having complications like CKD, Nephropathies, Autoimmune Disease, Osteoarthritis, Rheumatoid Arthritis, Renal Failure.
4. Patient having smaller joint pain but with normal uric acid level.
5. Patient taking medication for any other systematic illness
6. Pregnant and lactating Females. |
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
| Change in serum uric acid level from baseline to the end of the study. |
3 months and 6 months |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| Improvement in clinical symptoms & overall wellbeing during the study period. |
3 months & 6 months |
|
|
Target Sample Size
|
Total Sample Size="30"
Sample Size from India="30"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
20/01/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="6"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Hyperuricemia is a metabolic disorder characterized by increased serum uric acid levels and is associated with joint pain gout renal disorders and metabolic diseases. Its prevalence is rising across all age groups due to lifestyle factors obesity diabetes and hypertension. Conventional treatment includes drugs that lower uric acid levels but long term use is often associated with adverse effects and poor tolerance. Homoeopathy offers an individualized holistic approach aimed at correcting the underlying imbalance and improving the body ability to metabolize and excrete uric acid. This prospective case series study is designed to evaluate the effectiveness of individualized homoeopathic medicines in managing hyperuricemia across all age groups. The study focuses on changes in serum uric acid levels pain intensity and overall well being of patients. The findings may help establish homoeopathy as a safe effective and complementary treatment option for hyperuricemia and improve quality of life with minimal side effects |