| CTRI Number |
CTRI/2026/01/101671 [Registered on: 20/01/2026] Trial Registered Prospectively |
| Last Modified On: |
20/01/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Ayurveda
Other (Specify) [shatapushpa tail nasya & shatapushpa churna orally] |
| Study Design |
Randomized, Parallel Group, Multiple Arm Trial |
|
Public Title of Study
|
This study is being done to find out whether two Ayurvedic treatments—Shatapushpa Taila Nasya (oil put into the nose; Anethum sowa Roxb) and Shatapushpa Churna (herbal powder taken by mouth; Anethum sowa Roxb)—can help college students improve their memory, concentration, and learning ability |
|
Scientific Title of Study
|
Evaluation Of The Efficacy Of Shatapushpa Tail Nasya & Shatapushpa Churna In The Enhancement Of Medha (Intelligence Quotient) In College-Going Student-Randomized Controlled Clinical Trial |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
ClinicalTrials.gov |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Mrunal Sunil Kshirsagar |
| Designation |
MD Scholar |
| Affiliation |
Dr. D. Y. Patil College of Ayurved And Research Centre, Pimpri, Pune 18 |
| Address |
Dr D.Y.Patil College of Ayurved & Research Centre, Dr.D.Y.Patil Vidyapeeth (Deemed to be University), Sant Tukaram Nagar,Pimpri, Pune
Pune
MAHARASHTRA
411018
India |
| Phone |
8421622593 |
| Fax |
|
| Email |
kshirsagarmrunal4@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Vijaya Nyahalse |
| Designation |
Associate Professor Department of Kriya Sharir |
| Affiliation |
Dr. D. Y. Patil College of Ayurved And Research Centre, Pimpri, Pune 18 |
| Address |
Dr D.Y.Patil College of Ayurved & Research Centre, Dr.D.Y.Patil Vidyapeeth (Deemed to be University), Sant Tukaram Nagar,Pimpri, Pune
Pune
MAHARASHTRA
411018
India |
| Phone |
7709082385 |
| Fax |
|
| Email |
jiya.nyahalse11@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Dr Vijaya Nyahalse |
| Designation |
Associate Professor Department of Kriya Sharir |
| Affiliation |
Dr. D. Y. Patil College of Ayurved And Research Centre, Pimpri, Pune 18 |
| Address |
Dr D.Y.Patil College of Ayurved & Research Centre, Dr.D.Y.Patil Vidyapeeth (Deemed to be University), Sant Tukaram Nagar,Pimpri, Pune
Pune
MAHARASHTRA
411018
India |
| Phone |
7709082385 |
| Fax |
|
| Email |
jiya.nyahalse11@gmail.com |
|
|
Source of Monetary or Material Support
|
| Dr.DY Patil Vidyapeeth(Deemed to be University) ,Dr DY Patil college of Ayurved and Research center Pimpri.Pune |
|
|
Primary Sponsor
|
| Name |
Dr. Mrunal Sunil Kshirsagar |
| Address |
Dr. D. Y. Patil College of Ayurved And Research Centre, Dr.D.Y.Patil Vidyapeeth (Deemed to be university) Pimpri, Pune 18 |
| Type of Sponsor |
Other [Self] |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Mrunal Sunil Kshirsagar |
Dr. D. Y. Patil Ayurved Hospital and Research Centre, Pimpri, Pune -18 |
OPD No 5 ,Department of Kaya Chikitsa and Department of Kriya Sharir , Dr D.Y.Patil College Of Ayurved & Research Centre, Dr.D.Y.Patil Vidyapeeth (Deemed to be University), Sant Tukaram Nagar,Pimpri, Pune -411018
Pune
MAHARASHTRA |
8421622593
kshirsagarmrunal4@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| INSTITUTIONAL ETHICS COMMITTEE |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Healthy Human Volunteers |
College Going Student |
|
|
Intervention / Comparator Agent
|
| sno | Intervention/Comparator | Type | Drug-Type | Procedure Name | Details | | 1 | Intervention Arm | Procedure | - | nasyam/ nastam, नस्यम्/ नस्तम् | (Procedure Reference: Tiwari PV, editor. Kashyapa Samhita or Vriddha Jivakiya Tantra of Maharshi Kashyapa. 1st ed. Varanasi: Chaukhamba Visvabharati; 2014. p. 185-188, Procedure details: the procedure of Nasya should be done in early morning. Dip the Shatapusha taila Nasya bottle in lukewarm water. It should be lukewarm at the time of administration. Ask participant to lie down in supine position comfortably on bed with head low at about 45 degrees.The tip of participant's nose is then lifted gently by any relative (who can pour Shatapushpa taila drops) wih his or her index finger,Pour 2 drops of shatapusha taila in each nostril, Ask the participant to snuff it.Ask participant not to shake head or speak during Nasyavidhi and maintain supine position for
minimum 10 minutes after Nasyavidhi.Same should be done for 30 consecutive days.)
(1) Medicine Name: Shatapushpa taila, Reference: Tiwari PV, editor. Kashyapa Samhita or Vriddha Jivakiya Tantra of Maharshi Kashyapa. 1st ed. Varanasi: Chaukhamba Visvabharati; 2014. p. 185-188, Route: Nasal, Dosage Form: Bindu/ Drops/ Spray (Karna/ Nasa/ Netra/ Mukha), Dose: 2(drops), Frequency: od, Duration: 30 Days | | 2 | Comparator Arm | Drug | Classical | | (1) Medicine Name: Shatapushpa churna , Reference: Tiwari PV, editor. Kashyapa Samhita or Vriddha Jivakiya Tantra of Maharshi Kashyapa. 1st ed. Varanasi: Chaukhamba Visvabharati; 2014. p. 185-188, Route: Oral, Dosage Form: Churna/ Powder, Dose: 6(g), Frequency: bd, Bhaishajya Kal: Pragbhakta, Duration: 30 Days, anupAna/sahapAna: Yes(details: Madhu and Ghruta), Additional Information: |
|
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
30.00 Year(s) |
| Gender |
Both |
| Details |
Healthy volunteers (college going students) |
|
| ExclusionCriteria |
| Details |
PARTICIPANTS CURRENTLY ON ANY MEDICATION FOR ANY CONDITION
INDIVIDUALS WITH ANY PSYCHIATRIC ISSUE OR DISORDER |
|
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Method of Generating Random Sequence
|
Coin toss, Lottery, toss of dice, shuffling cards etc |
|
Method of Concealment
|
Other |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
This study is expected to measure enhancement in Medha (Intelligence Quotient) among participants in both intervention groups those receiving Shatapushpa taila Nasya and those receiving
Shatapushpa Churna.Thereby supporting the Medhya properties of Shatapushpa irrespective of the route , form and dose of administration |
This study is expected to show a significant enhancement in Medha (Intelligence Quotient) among participants in both intervention groups those receiving Shatapushpa taila Nasya and those receiving Shatapushpa Churna.Thereby supporting the Medhya properties of Shatapushpa irrespective of the route , form and dose of administration in 4 week (30 days) |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| nil |
nil |
|
|
Target Sample Size
|
Total Sample Size="80"
Sample Size from India="80"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
Phase 2 |
|
Date of First Enrollment (India)
|
09/02/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="6"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Yet Recruiting |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
This randomized controlled clinical trial aims to evaluate the efficacy of Shatapushpa Taila Nasya and Shatapushpa Churna in enhancing Medha (Intelligence Quotient) among college-going students. Participants will be randomly allocated into two groups using the lottery method. Group A will receive Shatapushpa Taila Nasya, administered in the morning at a dose of two drops in each nostril for 30 days, while Group B will receive Shatapushpa Churna at a dose of 6 g twice daily before food for the same duration. Baseline assessment of intelligence quotient will be carried out on Day 1 using the S.K. Pal and K.S. Misra Intelligence Scale, and post-intervention assessment will be conducted on Day 31 using the same scale. The study is expected to demonstrate a significant enhancement in Medha (Intelligence Quotient) in both intervention groups. |