| CTRI Number |
CTRI/2026/01/101792 [Registered on: 22/01/2026] Trial Registered Prospectively |
| Last Modified On: |
21/01/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Observational |
|
Type of Study
|
Follow Up Study |
| Study Design |
Other |
|
Public Title of Study
|
Study of blood ferritin levels to predict severity of acute pancreatitis |
|
Scientific Title of Study
|
Serum ferritin as a prognostic marker of severity in acute pancreatitis according to revised atlanta classification |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Arun Kumar Gupta |
| Designation |
Professor |
| Affiliation |
Sri Guru Ramdas University of Health Sciences |
| Address |
Unit4 Department of Surgery south division room no 1 , 2nd floor SGRD , Amritsar
Amritsar
PUNJAB
143501
India |
| Phone |
9855435868 |
| Fax |
|
| Email |
dr_arun_gupta@yahoo.co.in |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Arun Kumar Gupta |
| Designation |
Professor |
| Affiliation |
Sri Guru Ramdas University of Health Sciences |
| Address |
Unit4 Department of Surgery south division room no 1 , 2nd floor SGRD , Amritsar
Amritsar
PUNJAB
143501
India |
| Phone |
9855435868 |
| Fax |
|
| Email |
dr_arun_gupta@yahoo.co.in |
|
Details of Contact Person
Public Query
|
| Name |
Dr Navjot Singh |
| Designation |
Junior Resident |
| Affiliation |
Sri Guru Ramdas University of Health Sciences |
| Address |
Unit4 Department of Surgery south division , 2nd floor SGRD , Amritsar , room no.3
Amritsar
PUNJAB
143501
India |
| Phone |
7888509652 |
| Fax |
|
| Email |
navjot53450@gmail.com |
|
|
Source of Monetary or Material Support
|
|
|
Primary Sponsor
|
| Name |
Sri guru ram das university of health sciences |
| Address |
Department of surgery
Sri guru ram das university of health sciences amritsar punjab |
| Type of Sponsor |
Private medical college |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| DrArun Kumar Gupta |
Sri guru ramdas university of health sciences amritsar punjab |
Department of surgery , south division , room no.1, Sri guru ramdas university of health sciences amritsar punjab
Amritsar
PUNJAB |
9855435868
dr_arun_gupta@yahoo.co.in |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional Ethics Committee |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: K859||Acute pancreatitis, unspecified, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Intervention |
Nil |
Nil |
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
99.00 Year(s) |
| Gender |
Both |
| Details |
patient older than 18 years diagnosed with acute pancreatitis |
|
| ExclusionCriteria |
| Details |
1)Patients who were hospitalized two or several times within three months
2)Patients younger than 18 years of age
3)Serious underlying diseases affecting the detection of SF, such as a history of renal failure and patients with pancreatic tumors.
4)Previous diagnosis of cancer
5)pregnant women |
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
| difference in mean serum ferritin levels among patients with mild, moderately severe and severe acute pancreatitis as per revised atlanta classification at admission |
1) at admission ( baseline )
2) at 48 hours /2 days
3) at 4 week |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| NIL |
NIL |
|
|
Target Sample Size
|
Total Sample Size="60"
Sample Size from India="60"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
01/02/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="6"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Yet Recruiting |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Acute pancreatitis (AP) is a common inflammatory condition with a highly variable clinical course ranging from mild, self-limiting illness to severe, life-threatening disease associated with organ failure and high mortality. Early and accurate assessment of disease severity is crucial for optimizing management, preventing complications, and improving outcomes. Traditional prognostic scoring systems are often complex and time-consuming, necessitating the search for simple, reliable biomarkers. Serum ferritin, an acute-phase reactant that reflects systemic inflammation and oxidative stress, has emerged as a potential prognostic marker in various inflammatory and critical illnesses. Given its ease of measurement and established clinical availability, evaluating serum ferritin levels in relation to the Revised Atlanta Classification may provide an effective tool for early risk stratification in acute pancreatitis, thereby enhancing clinical decision-making and patient care. |