| CTRI Number |
CTRI/2026/01/100603 [Registered on: 08/01/2026] Trial Registered Prospectively |
| Last Modified On: |
08/01/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Physiotherapy (Not Including YOGA) |
| Study Design |
Randomized, Parallel Group, Multiple Arm Trial |
|
Public Title of Study
|
This study checks whether hands-on physiotherapy and muscle-relaxing stretches can reduce pain, improve posture walking and strength in people with lower back muscle imbalance |
|
Scientific Title of Study
|
Effects of central and unilateral PA glide along with post isometric relaxation on lumbar spine posture walking speed altered lower limb biomechanics pain and strength in individuals with lower cross syndrome |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Nachiketa Sharma |
| Designation |
Post Graduate Student |
| Affiliation |
SGT University |
| Address |
SGT University Room number 418 4th floor department of physiotherapy B block Gurugram Haryana 122505
Gurgaon
HARYANA
122505
India |
| Phone |
9899783356 |
| Fax |
|
| Email |
nachiketa985@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Lalli M Singh |
| Designation |
Assistant Professor |
| Affiliation |
SGT University |
| Address |
SGT University Room number 418 4th floor department of physiotherapy B block Gurugram Haryana 122505
Gurgaon
HARYANA
122505
India |
| Phone |
9558386479 |
| Fax |
|
| Email |
singhlalli06@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Nachiketa Sharma |
| Designation |
Post Graduate Student |
| Affiliation |
SGT University |
| Address |
SGT University Room number 418 4th floor department of physiotherapy B block Gurugram Haryana 122505
Gurgaon
HARYANA
122505
India |
| Phone |
9899783356 |
| Fax |
|
| Email |
nachiketa985@gmail.com |
|
|
Source of Monetary or Material Support
|
|
|
Primary Sponsor
|
| Name |
Nachiketa Sharma |
| Address |
3 block M Sharma Colony Budh Vihar Phase 2 Delhi 110086 |
| Type of Sponsor |
Other [self] |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Nachiketa Sharma |
SGT Hospital and Research institute |
SGT University room number 418 department of physiotherapy B block Gurugram Haryana 122505
Gurgaon
HARYANA |
9899783356
nachiketa985@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional ethical committee of faculty of physiotherapy SGT University |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: M545||Low back pain, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Comparator Agent |
Conventional training |
The control group received a home exercise program consisting of basic stretching mobility and postural exercises performed once daily without supervised physiotherapy intervention for 4 weeks 3 sessions per week |
| Intervention |
Post isometric relaxation
Central and unilateral posterior anterior glide |
This exercise intervention is given to the experimental group for the duration of 4 weeks alternatively 3 sessions in a week
Post isometric relaxation for tight lumbar and hip muscles
For 7 to 10 second hold with 3 repetitions 2 sets per muscle for 15 minutes
Along with central and unilateral posteroanterior mobilization of the lumbar spine to reduce pain improve posture and normalize gait
Central posteroanterior glide on lumbar vertebra L1 to L5 of grade 1 to grade 2 for pain and grade 3 for stiffness with oscillations of 2 to 3 per seconds for the duration of 60 seconds per level
Unilateral posteroanterior glide at unilateral facet joints of lumbar spine L1 to L5 of grade 2 to 3 with oscillations 2 to 3 per seconds for the duration of 60 seconds 1 to 2 segments per side |
|
|
Inclusion Criteria
|
| Age From |
20.00 Year(s) |
| Age To |
40.00 Year(s) |
| Gender |
Both |
| Details |
Individuals between the ages of 20 to 40 years
Regardless of gender
Experience chronic nonspecific low back pain for a duration of three months or longer
They also exhibit changes in the biomechanics of their lower limbs during walking
Participants must be capable of walking without assistance and agree to take part in the study |
|
| ExclusionCriteria |
| Details |
People who have undergone spinal surgery
Have specific spinal problems
Suffer from neurological or systemic conditions
Experience muscle issues in their lower limbs that impact walking
Are pregnant
Have obesity BMI Greater than 30 kg per meter squared
Have recently completed physical therapy or received medication for lower back pain
Have contraindication for manual therapy were not included |
|
|
Method of Generating Random Sequence
|
Permuted block randomization, fixed |
|
Method of Concealment
|
Sequentially numbered, sealed, opaque envelopes |
|
Blinding/Masking
|
Participant Blinded |
|
Primary Outcome
|
| Outcome |
TimePoints |
| Pain |
Baseline and 4 weeks |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
Lumbar spine posture
Walking speed
Lower limb biomechanics
Muscle strength |
Baseline and 4weeks |
|
|
Target Sample Size
|
Total Sample Size="52"
Sample Size from India="52"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
19/01/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="0"
Months="1"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Need of the Study Lower Cross Syndrome is a prevalent postural issue associated with muscular imbalances altered lumbar alignment walking difficulties and persistent low back discomfort This is particularly relevant for young to middle aged individuals who have sedentary habits Although various physiotherapy methods can assist in alleviating low back pain there is a lack of evidence regarding the combined effects of central and unilateral posterior anterior glide in addition to post isometric relaxation This blend of technique may influence posture ambulation lower extremity biomechanics pain level and muscle strength in individuals affected by lower cross syndrome Consequently it is crucial to evaluate the effectiveness of these specific manual therapy methods for this demographic Significance of the study This study will provide evidence on the effectiveness of combined manual therapy techniques in improving pain posture gait and muscle strength in individuals with Lower Cross Syndrome The findings may help physiotherapists select targeted evidence based interventions for managing postural low back pain and associated movement impairments thereby improving functional outcomes and quality of life |