Periodontal diseases, primarily caused by microbial biofilm, remain one of the most prevalent oral health problems and a major reason for tooth loss in adults. Although conventional scaling and root planing (SRP) with hand and ultrasonic instruments has long been considered the gold standard for biofilm removal, it is often time-consuming. technique-sensitive, and associated with adverse effects such as cementum loss. postoperative sensitivity, and considerable patient discomfort. These limitations highlight the need for less invasive, more efficient, and patient-friendly alternatives. Guided Biofilm Therapy (GBT), which integrates air-polishing with ultrasonic instrumentation, offers a systematic and minimally invasive approach that may reduce treatment time, enhance patient comfort, and improve clinical efficiency while maintaining therapeutic effectiveness. Therefore, it is necessary to evaluate and compare GBT with conventional scaling to determine its clinical relevance, patient acceptance, and practitioner preference.