| CTRI Number |
CTRI/2026/03/106377 [Registered on: 17/03/2026] Trial Registered Prospectively |
| Last Modified On: |
17/03/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Drug
Ayurveda |
| Study Design |
Randomized, Parallel Group Trial |
|
Public Title of Study
|
Access the efficacy of vacha potali nasya in
kaphaja pratishyaya with reference to chronic rhinitis |
|
Scientific Title of Study
|
Randomised controlled trial to evaluate the efficacy of vacha potali nasya in
kaphaja pratishyaya with reference to chronic rhinitis. |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Ashish Bhimsing Thakur |
| Designation |
PG Scholar Shalakyatantra |
| Affiliation |
PMTs Ayurved college Shevgaon Dist ahilyanagar |
| Address |
PMTs Ayurved college Shevgaon and shri eknath ayurved rugnalaya District Ahilyanagar
Maharashtra
India
Ahmadnagar
MAHARASHTRA
414502
India |
| Phone |
8329597397 |
| Fax |
|
| Email |
ashishthakur20797@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Swati Sarawade |
| Designation |
Guide and HOD SHALAKYATANTRA department |
| Affiliation |
PMTs Ayurved college Shevgaon dist ahilyanagar |
| Address |
OPD NO8 shalakya department PMTs Ayurved college Shevgaon Dist Ahilyanagar
Ahmadnagar
MAHARASHTRA
414502
India |
| Phone |
9422935125 |
| Fax |
|
| Email |
drsarwadeswativ@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Dr Ashish Bhimsing Thakur |
| Designation |
PG Scholar Shalakyatantra |
| Affiliation |
PMTs Ayurved college Shevgaon Dist ahilyanagar |
| Address |
PMTs Ayurved college Shevgaon andshri eknath ayurved rugnalaya Dist Ahilyanagar 414502
Maharashtra
India
Ahmadnagar
MAHARASHTRA
414502
India |
| Phone |
8329597397 |
| Fax |
|
| Email |
ashishthakur20797@gmail.com |
|
|
Source of Monetary or Material Support
|
| PMTs Ayurved College And Shri Eknath Ayurved Rugnalaya, Shevgaon, Akhegaon Road Tal Shevgaon Dist Ahilyanagar, MAHARASHTRA ,INDIA-414502 |
|
|
Primary Sponsor
|
| Name |
Dr Ashish Bhimsing Thakur |
| Address |
PMTs Ayurved College And Shri Eknath Ayurved Rugnalaya, Shevgaon Akhegaon Road Tal Shevgaon Dist Ahilyanagar MAHARASHTRA INDIA-414502 |
| Type of Sponsor |
Private medical college |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Ashish Bhimsing Thakur |
PMT Ayurved College Shevgaon |
OPD No 8 Shalakya Tantra Department PMT Ayurved College Shevgaon Dist Ahilyanagar
Ahmadnagar
MAHARASHTRA |
8329597397
ashishthakur20797@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| PMT Ayurved College Ethical Institutional Commitee |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition:J988||Other specified respiratory disorders. Ayurveda Condition: PRATISYAYAH/PINASAH, (2) ICD-10 Condition:J988||Other specified respiratory disorders. Ayurveda Condition: PRATISYAYAH/PINASAH, (3) ICD-10 Condition:J988||Other specified respiratory disorders. Ayurveda Condition: PRATISYAYAH/PINASAH, |
|
|
Intervention / Comparator Agent
|
| sno | Intervention/Comparator | Type | Drug-Type | Procedure Name | Details | | 1 | Intervention Arm | Procedure | - | nasyam/ nastam, नस्यम्/ नस्तम् | (Procedure Reference: Sushrut Utartantra, Procedure details: 1) Nasya procedure should be done in special room which is devoid of heavy
breeze and dust.
2) Patient should be down in supine position on a table and Abhyanga with
lukewarm oil done over face, scalp, temporal and neck region.
3) After completion of Abhyanga Mridu Sweda was done by covering the eyes.
Pradhan karma
1) Patient lie down in supine position with Head and Neck are low position .
2) Patient asked to hold the Potali and snuff the Churna with closing one nostril.
Paschat Karma
After Nasya karma give Kavala with koshna Jala)
(1) Medicine Name: vacha , Reference: yog ratnakar, Route: Nasal, Dosage Form: Churna/ Powder, Dose: 3(g), Frequency: od, Duration: 7 Days | | 2 | Comparator Arm | Procedure | - | nasyam/ nastam, नस्यम्/ नस्तम् | (Procedure Reference: sushruta chikitsasthana, Procedure details: 1) Patient lie down in supine position with Head & Neck are low position .
2) Patient asked to hold the Potali and snuff the Churna with closing one nostril.
Paschat Karma
After Nasya karma give Kavala with koshna Jala.)
(1) Medicine Name: chaturjataka churna, Reference: yogratnakara, Route: Nasal, Dosage Form: Churna/ Powder, Dose: 125(mg), Frequency: od, Duration: 7 Days |
|
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
60.00 Year(s) |
| Gender |
Both |
| Details |
1)Patients with classical sign and symptoms of Kaphaja Pratishyaya.(Nasa
Strav,Nasa Kandu).
2) Patient having age group 18 to 60 yrs.Will be irrespective of gender, religion,
occupation, socio-economic status.
3) Patient who gave written consent for study. |
|
| ExclusionCriteria |
| Details |
1)Patient with other systemic diseases k/c/o HTN, DM, Asthma, TB, AIDS ,Covid
19 etc. 2)Patients other than Pratishyaya , Allergic Rhinitis, Atropic Rhinitis and
other nasal disorder, Nasal polyp, Ca of nasopharynx etc.
3) Chronicity of disease more than 2 months.
4) Patient suffering from Nasagat krumi,Gandh Nyan nashta,Drustha Pratishya. |
|
|
Method of Generating Random Sequence
|
Computer generated randomization |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Open Label |
|
Primary Outcome
|
| Outcome |
TimePoints |
To evaluate the efficacy of Vacha Potali Nasya in the treatment of Kaphaja
Pratishyaya with reference to Chronic Rhinitis |
7 Days |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
1.To review the Iiterature of Kaphaja Pratishyaya with reference to Chronic
Rhinitis in view of Ayurveda and Modern.
2.To review the literature of Vacha Potali Nasya in Kaphaja Pratishyaya
3.To evaluate the efficacy of Chaturjatak Churna Nasya in Kaphaja Pratishyaya.
4.To compare between Vacha Potali Nasya and Chaturjatak Churna Nasya in
Kaphaja Pratishyaya.
5.To observe the adverse drug reaction. |
7 Days |
|
|
Target Sample Size
|
Total Sample Size="76"
Sample Size from India="76"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
Phase 2/ Phase 3 |
|
Date of First Enrollment (India)
|
30/03/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
30/03/2026 |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="6"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Yet Recruiting |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Regular practice of Nasya helps clear the nasal passages and sinuses, improving the overall health of the respiratory tract. It aids in relieving congestion, allergies, sinusitis, and other respiratory disorders. Dry powder preparation increase mucocilliary clearance in patients of Pratishyayaand dry powder may also affect the Rhinological properties of the mucous and clearing increases transportability of mucus. As a vital part of Panchakarma, it is both preventive and curative, helping with chronic conditions and promoting daily well-being. Vacha(Acorus calamus Linn. (Acoraceae)) Isa traditional Indian medicinal herb, which is practiced to treat a wide range of health ailments, including neurological, gastrointestinal, respiratory, metabolic, kidney, and liver disorders. |