CTRI

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CTRI Number

CTRI/2026/03/106199 [Registered on: 13/03/2026] Trial Registered Prospectively

Last Modified On:

12/03/2026

Post Graduate Thesis

Yes

Type of Trial

Interventional

Type of Study

Physiotherapy (Not Including YOGA)

Study Design

Randomized, Parallel Group Trial

Public Title of Study

Effect of Balance and Proprioception Exercises Compared with Strengthening Exercises for Preventing Recurrent Ankle Sprains in Young Adults

Scientific Title of Study

Comparative Effectiveness of Proprioceptive and Balance Training versus Conventional Strengthening in Improving Stability and Reducing Recurrence of Ankle Sprains in Young Adults.

Trial Acronym

nil

Secondary IDs if Any

Secondary ID	Identifier
NIL	NIL

Details of Principal Investigator or overall Trial Coordinator (multi-center study)

Name	Vishesh Kumar
Designation	Post Graduate student
Affiliation	Prakash Institute of Physiotherapy, Rehabilitation and Allied Medical Sciences
Address	Prakash Institute of Physiotherapy Rehabilitation and Allied Medical Sciences Gautam budh nagar Uttar Pradesh 201303 Gautam Buddha Nagar UTTAR PRADESH 201303 India
Phone	8766258369
Fax
Email	visheshkumar1700@gmail.com

Details of Contact Person
Scientific Query

Name	PUJA SHARMA
Designation	Associate Professor
Affiliation	Prakash Institute of Physiotherapy, Rehabilitation and Allied Medical Sciences
Address	Prakash Institute of Physiotherapy Rehabilitation and Allied Medical Sciences Gautam budh nagar Uttar Pradesh 201303 Gautam Buddha Nagar UTTAR PRADESH 201303 India
Phone	9873252361
Fax
Email	s.puja47@gmail.com

Details of Contact Person
Public Query

Name	dr Puja Sharma
Designation	Associate Professor
Affiliation	Prakash Institute of Physiotherapy, Rehabilitation and Allied Medical Sciences
Address	Prakash Institute of Physiotherapy Rehabilitation and Allied Medical Sciences Gautam budh nagar Uttar Pradesh 201303 Gautam Buddha Nagar UTTAR PRADESH 201303 India
Phone	9873252361
Fax
Email	s.puja47@gmail.com

Source of Monetary or Material Support

NIL

Primary Sponsor

Name	VISHESH KUMAR
Address	Prakash Institute of Physiotherapy Rehabilitation and Allied Medical Sciences Gautam budh nagar Uttar Pradesh 201303
Type of Sponsor	Other [SELF]

Details of Secondary Sponsor

Name	Address
NIL	NIL

Countries of Recruitment

India

Sites of Study

No of Sites = 1
Name of Principal Investigator	Name of Site	Site Address	Phone/Fax/Email
Vishesh Kumar	Flexlife Physiotherapy and Rehabilitation Center	E 303 Block E Delta I Greater Noida Gautam Buddha Nagar UTTAR PRADESH	8766258369 Visheshkumar1700@gmail.com

Details of Ethics Committee

No of Ethics Committees= 1
Name of Committee	Approval Status
PIPRAMS	Approved

Regulatory Clearance Status from DCGI

Status

Not Applicable

Health Condition / Problems Studied

Health Type	Condition
Patients	(1) ICD-10 Condition: M799\|\|Soft tissue disorder, unspecified,

Intervention / Comparator Agent

Type	Name	Details
Comparator Agent	conventional physiotherapy	Participants in Group B will receive conventional physiotherapy consisting of cryotherapy if required, ankle range of motion exercises, stretching exercises and theraband strengthening exercises for dorsiflexion, plantarflexion, inversion and eversion. The treatment duration and frequency will be the same as the intervention group with three sessions per week for twelve weeks.
Intervention	Proprioceptive and Balance Training with Conventional Physiotherapy	Participants in Group A will receive conventional physiotherapy along with proprioceptive and balance training exercises. Conventional physiotherapy will include cryotherapy if required, active ankle range of motion exercises, gastrocnemius and soleus stretching and theraband strengthening exercises for dorsiflexion, plantarflexion, inversion and eversion. In addition, participants will undergo progressive proprioceptive and balance training including single leg stance exercises, foam surface balance training, perturbation training, hop stabilization drills and agility ladder exercises. The intervention will be conducted three sessions per week for a duration of twelve weeks.

Inclusion Criteria

Age From	18.00 Year(s)
Age To	25.00 Year(s)
Gender	Both
Details	Young adults aged 18 to 25 years with a history of at least one lateral ankle sprain within the past twelve months and diagnosed with chronic ankle instability defined by a Cumberland Ankle Instability Tool score of less than or equal to twenty four. Participants must be able to bear weight independently and willing to participate in the study.

ExclusionCriteria

Details

Participants with acute ankle sprain within the past six weeks.Individuals with grade three ankle sprain requiring immobilization.

History of ankle fracture or ankle surgery.

Neurological disorders affecting balance.

Systemic inflammatory joint diseases.

Method of Generating Random Sequence

Computer generated randomization

Method of Concealment

Sequentially numbered, sealed, opaque envelopes

Blinding/Masking

Open Label

Primary Outcome

Outcome	TimePoints
Y Balance Test Star Excursion Balance Test	Baseline 6 weeks 10 weeks 3 months follow up

Secondary Outcome

Outcome	TimePoints
Self reported ankle instability measured using Cumberland Ankle Instability Tool Functional outcome measured using Foot and Ankle Ability Measure Recurrence of ankle sprain during follow up	Baseline 6 Weeks 12 Weeks 3 Month Follow Up

Target Sample Size

Total Sample Size="60"
Sample Size from India="60"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials"

Phase of Trial

N/A

Date of First Enrollment (India)

01/04/2026

Date of Study Completion (India)

Applicable only for Completed/Terminated trials

Date of First Enrollment (Global)

Date Missing

Date of Study Completion (Global)

Applicable only for Completed/Terminated trials

Estimated Duration of Trial

Years="0"
Months="11"
Days="0"

Recruitment Status of Trial (Global)

Not Applicable

Recruitment Status of Trial (India)

Not Yet Recruiting

Publication Details

N/A

Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?

Response - NO

Brief Summary

Recurrent ankle sprains are one of the most common musculoskeletal injuries among young adults and may lead to chronic ankle instability characterized by repeated episodes of instability, pain and functional limitation. Conventional physiotherapy programs commonly focus on strengthening and stretching exercises but may not fully address deficits in proprioception and neuromuscular control.

Proprioceptive and balance training aims to improve joint position sense, neuromuscular coordination and dynamic stability of the ankle joint. This randomized controlled trial aims to compare the effectiveness of proprioceptive and balance training combined with conventional physiotherapy versus conventional physiotherapy alone in improving balance, functional outcomes and preventing recurrence of ankle sprains in young adults.

A total of sixty participants aged between eighteen and twenty five years with chronic ankle instability will be recruited and randomly allocated into two groups. Outcome measures including Y Balance Test, Star Excursion Balance Test, Cumberland Ankle Instability Tool and Foot and Ankle Ability Measure will be assessed at baseline, six weeks and twelve weeks. Participants will also be followed for three months to monitor recurrence of ankle sprains.

The study will help determine whether proprioceptive and balance training provides superior improvement in ankle stability and functional outcomes compared with conventional strengthening programs.