| CTRI Number |
CTRI/2026/04/107495 [Registered on: 02/04/2026] Trial Registered Prospectively |
| Last Modified On: |
02/04/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Other (Specify) [Growth factor concentrate and topical minoxidil] |
| Study Design |
Other |
|
Public Title of Study
|
Role of growth factor concentrate in androgenetic alopecia- a hospital based comparative study |
|
Scientific Title of Study
|
Role of Growth Factor Concentrate in Androgenetic Alopecia- a hospital based comparative study |
| Trial Acronym |
Nil |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Tanvi Singla |
| Designation |
Junior resident |
| Affiliation |
Shri ram murti smarak institute of medical sciences |
| Address |
Shri ram murti smarak institute of medical sciences, bhojipura, abheypur keshonpur Uttar Pradesh 243202
Bareilly
UTTAR PRADESH
243202
India |
| Phone |
8607334671 |
| Fax |
|
| Email |
Tanvisingla23@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Madhur Kant Rastogi |
| Designation |
Professor |
| Affiliation |
Shri ram murti smarak institute of medical sciences |
| Address |
SRMS Bareilly
Shri ram murti smarak institute of medical sciences, bhojipura, abheypur keshonpur Uttar Pradesh 243202
Bareilly
UTTAR PRADESH
243202
India |
| Phone |
980815847 |
| Fax |
|
| Email |
Kantmadhur@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Dr Madhur Kant Rastogi |
| Designation |
Professor |
| Affiliation |
Shri ram murti smarak institute of medical sciences |
| Address |
SRMS Bareilly
Shri ram murti smarak institute of medical sciences, bhojipura, abheypur keshonpur Uttar Pradesh 243202
Bareilly
UTTAR PRADESH
243202
India |
| Phone |
980815847 |
| Fax |
|
| Email |
Kantmadhur@gmail.com |
|
|
Source of Monetary or Material Support
|
| Tanvi Singla (self)
SRMS IMS BAREILLY |
|
|
Primary Sponsor
|
| Name |
srms medical college |
| Address |
shri ram murti smarak institute of medical sciences bhojipura abheypur keshonpur Uttar Pradesh 243202 |
| Type of Sponsor |
Private medical college |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Tanvi Singla |
Shri Ram Murti Smarak institute of medical sciences |
dermatology department room 101 Bhojipura Abheypur Keshonpur
Bareilly
UTTAR PRADESH |
8607334671
Tanvisingla23@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional ethics committee |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: L00-L99||Diseases of the skin and subcutaneous tissue, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Intervention |
Growth factor concentrate |
Use of GFC for treatment of AGA |
| Comparator Agent |
Topical minoxidil |
Use of topical minoxidil for treatment of AGA |
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
60.00 Year(s) |
| Gender |
Both |
| Details |
All diagnosed with stable type of Androgenetic alopecia.
Patients with hair type II-V according to Norwood-Hamilton scale for males.
Patients with hair type I-II according to Ludwig scale for females.
Patients who are willing to abstain from other treatments.
Patients who have completed written consent form.
|
|
| ExclusionCriteria |
| Details |
Patients who refused to participate.
Patients with other type of alopecia as a diagnosis.
Patients suffering from seborrheic dermatitis, tines capitis or any other scalp infection.
Patients undergoing any form of chemo or radiotherapy.
Patients found to be allergic to constituents of GFC.
Pregnant and lactating females, chronic smokers or alcoholics.
Patients who have taken any treatment for past 3 months. |
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
| Improvement in hair density across 3 sittings |
Assessment done at baseline then monthly for 3 months followed by final assessment at 6 months. |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| Lack of improvement at the end of 6 months |
6 months. |
|
|
Target Sample Size
|
Total Sample Size="30"
Sample Size from India="30"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
Phase 2 |
|
Date of First Enrollment (India)
|
15/04/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="6"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
This is a trial to compare the effects of growth factor concentrate vs topical minoxidil for treatment of Androgenetic alopecia. The results will be evaluated based on Norwood-Hamilton score, Ludwig score, Sinclaire grading and Modified global photographic assessment score which will be recorded on every visit. Sittings will be done at monthly intervals for 3 months and then at 6 months. At the end of 6 months, comparison will be done based on these scores. |