Hypothyroidism is a hypo-metabolic clinical state resulting from inadequate production of thyroid hormone. Among endocrine abnormalities thyroid diseases are the most common both in India and worldwide. The prevalence of hypothyroidism in India is 11percent compared with only 2 percent-4.6 percent in the Western population Women are affected approximately six times more frequently than men. Symptoms of hypothyroidism include lethargy dry hair and skin cold intolerance hair loss difficulty in concentration poor memory constipation weight gain with poor appetite dyspnea hoarse voice muscle cramping and menorrhagia.The normal as well as the abnormal function of the thyroid gland can be correlated to the healthy and altered status of Agni While analyzing the signs and symptoms of Hypothyroidism in Ayurvedic view in hypothyroidism, there is abnormality of Jatharagni and Dhatwagni is seen along with abnormality of Vata and Kapha dosha  Kanchanara Guggulu is a classical ayurvedic formulation which is proven effective in treating Hypothyroidism and other metabolic disorders. Pranayama is generally defined as breath control  The breath is the most vital process of the body It influences the activities of each and every cell and most importantly is intimately linked with the performance of the brain In Hatayoga Pradeepika it is mentioned that Ujjayi Pranayama removes Kapha from the throat and stimulates the Agni  The vibration of the humming sound in the Bhramari Pranayama creates a soothing effect on the mind and nervous system and it eliminates throat ailments. Available treatment options for thyroid dysfunctions are hormone replacement therapy antithyroid medications radioactive iodine therapy beta-blockers to manage symptoms and in some cases, surgery. These treatments can impose a financial burden on patients. Pranayama is a cost-effective mind-body approach that is simple to practice  Hence this study is designed to evaluate the effect of Ujjayi Pranayama with Kanchanara Guggulu and Bhramari Pranayama with Kanchanara Guggulu and also to compare their efficacy with one another in hypothyroidism