| CTRI Number |
CTRI/2026/03/106837 [Registered on: 24/03/2026] Trial Registered Prospectively |
| Last Modified On: |
17/03/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Observational |
|
Type of Study
|
Cross Sectional Study |
| Study Design |
Single Arm Study |
|
Public Title of Study
|
Exploring the relation between high blood pressure and constipation in the age group of 35-55 years. |
|
Scientific Title of Study
|
A cross sectional study to find relation between Hypertension and Shakrutgraha (constipation) in the age group of 35-55 years. |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Pavankumar Raju Marmat |
| Designation |
PG Scholar |
| Affiliation |
PDEAs College of Ayurved and Research Centre Nigdi, Pune |
| Address |
PDEAs College of Ayurved and Research Centre Kriya Sharir Department, Nigdi, Pune Maharashtra 411044, India
Pune
MAHARASHTRA
411044
India |
| Phone |
8177847672 |
| Fax |
|
| Email |
marmatpavan123@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Swati Chobhe |
| Designation |
Professor and HOD |
| Affiliation |
PDEAs College of Ayurved and Research Centre Nigdi, Pune |
| Address |
PDEAs College of Ayurved and Research Centre Kriya Sharir Department, Nigdi, Pune Maharashtra 411044, India
Pune
MAHARASHTRA
411044
India |
| Phone |
9850716124 |
| Fax |
|
| Email |
chobheswati@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Dr Swati Chobhe |
| Designation |
Professor and HOD |
| Affiliation |
PDEAs College of Ayurved and Research Centre Nigdi, Pune |
| Address |
PDEAs College of Ayurved and Research Centre Kriya Sharir Department, Nigdi, Pune Maharashtra 411044, India
Pune
MAHARASHTRA
411044
India |
| Phone |
9850716124 |
| Fax |
|
| Email |
chobheswati@gmail.com |
|
|
Source of Monetary or Material Support
|
| Kriya Sharir Department, PDEAs College of Ayurved and Research Centre Sector 25, Pradhikaran, Nigdi, Pune 411044 Maharashtra |
|
|
Primary Sponsor
|
| Name |
PDEAs College of Ayurved and Research Centre Nigdi, Pune |
| Address |
PDEAs College of Ayurved and Research Centre Sector 25, Pradhikaran, Nigdi, Pune 411044 Maharashtra |
| Type of Sponsor |
Private medical college |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Pavankumar Marmat |
PDEAS college of Ayurved research centre nigdi |
Kriyasharir department ground floor PDEAS college of Ayurved and research centre Nigdi
Pune
MAHARASHTRA |
8177847672
marmatpavan123@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Chairperson Institutional Ethics Commitee |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition:I10-I16||Hypertensive diseases. Ayurveda Condition: RAKTAVAHASROTODUSHTIH, |
|
|
Intervention / Comparator Agent
|
| sno | Intervention/Comparator | Type | Drug-Type | Procedure Name | Details |
|
| Intervention |
Nil |
Nil |
|
|
Inclusion Criteria
|
| Age From |
35.00 Year(s) |
| Age To |
55.00 Year(s) |
| Gender |
Both |
| Details |
1) Adults aged 35 to 55 years.
2) Patients diagnosed with hypertension for at least 6 months.
3) Irrespective of gender. |
|
| ExclusionCriteria |
| Details |
1) Hypertensive Patients having history of other systemic diseases (renal diseases, endocrine diseases, individuals on oral hypoglycemic drugs)
2) Individuals with addictions like tobacco, smoking, and alcohol.
3) Pregnancy-induced hypertension.
4) History of recent major surgery or hospitalization. |
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
| To study the relation between hypertension and shakrutgraha (constipation) in the age group of 33-55 years. |
One time |
|
|
Secondary Outcome
|
|
|
Target Sample Size
|
Total Sample Size="100"
Sample Size from India="100"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
03/04/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="6"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Why this study is important: Hypertension is a growing lifestyle disorder, and identifying overlooked behavioral factor Shakrut-graha (Constipation) can aid in prevention and early management, especially in the 35–55 age group. What makes it unique: This is study attempting to correlate Shakrut-graha (Constipation) with a modern clinical condition hypertension in 35-55 years aged population, using both classical concepts and clinical assessment. Practical implications: The findings may help in developing lifestyle-based preventive guidelines, integrating importance of lifestyle strategies as mentioned in ayurveda, and increasing awareness in healthcare workers and common people about the impact of Shakrut-graha (Constipation) on hypertension. |