| CTRI Number |
CTRI/2026/03/105142 [Registered on: 02/03/2026] Trial Registered Prospectively |
| Last Modified On: |
28/02/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Physiotherapy (Not Including YOGA) |
| Study Design |
Randomized Factorial Trial |
|
Public Title of Study
|
Role of Nerve Movement Exercises in Managing Leg Pain During Pregnancy |
|
Scientific Title of Study
|
Effect of Neural Mobilization on Radiating Pain in Lower Limb among Pregnant Women. |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Suvarna Suman |
| Designation |
MPT student |
| Affiliation |
sharda university |
| Address |
DEPARTMENT OF PHYSIOTHERAPY, SHARDA SCHOOL OF ALLIED HEALTH SCIENCES, SHARDA UNIVERSITY, GREATER NOIDA, UTTAR PRADESH
Gautam Buddha Nagar UTTAR PRADESH 201310 India |
| Phone |
9123474201 |
| Fax |
|
| Email |
Suvarnasuman9955@gmail.com |
|
Details of Contact Person Scientific Query
|
| Name |
APOORVA TIWARI |
| Designation |
ASSISTANT PROFESSOR |
| Affiliation |
sharda university |
| Address |
DEPARTMENT OF PHYSIOTHERAPY, SHARDA SCHOOL OF ALLIED HEALTH SCIENCES, SHARDA UNIVERSITY, GREATER NOIDA, UTTAR PRADESH
Gautam Buddha Nagar UTTAR PRADESH 201310 India |
| Phone |
9335692366 |
| Fax |
|
| Email |
apoorva.tiwari@sharda.ac.in |
|
Details of Contact Person Public Query
|
| Name |
APOORVA TIWARI |
| Designation |
ASSISTANT PROFESSOR |
| Affiliation |
sharda university |
| Address |
DEPARTMENT OF PHYSIOTHERAPY, SHARDA SCHOOL OF ALLIED HEALTH SCIENCES, SHARDA UNIVERSITY, GREATER NOIDA, UTTAR PRADESH
UTTAR PRADESH 201310 India |
| Phone |
9335692366 |
| Fax |
|
| Email |
apoorva.tiwari@sharda.ac.in |
|
|
Source of Monetary or Material Support
|
| Department of Physiotherapy, Sharda School of Allied Health Sciences, Sharda University, Greater Noida, Uttar Pradesh, India, 201310 |
|
|
Primary Sponsor
|
| Name |
Department of Physiotherapy |
| Address |
Department of Physiotherapy, Sharda School of Allied Health Sciences, Sharda University, Greater Noida, Uttar Pradesh, India, 201310 |
| Type of Sponsor |
Research institution and hospital |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Apoorva Tiwari |
Sharda hospital |
Department Of Physiotherapy, Sharda Hospital f block 1st floor, Sharda School Of Allied Health Sciences, Sharda University, Greater Noida, Uttar Pradesh Gautam Buddha Nagar UTTAR PRADESH |
9335692366
apoorva.tiwari@sharda.ac.in |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional Ethics Comittee |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: M00-M99||Diseases of the musculoskeletal system and connective tissue, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Comparator Agent |
Control group |
Conventional exercises only |
| Intervention |
Experimental group |
Neural mobilization + Conventional exercises |
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
40.00 Year(s) |
| Gender |
Female |
| Details |
1. Gestation period 4-38 weeks.
2. Women having low back pain with radiating pain in lower Limb.
3. Age 18-40 years.
4. Patients who are willing to participate. |
|
| ExclusionCriteria |
| Details |
1.Age more than 40 years and less than 18 years.
2.Past history of injury.
3.Past history of surgery.
4.Any other neurological or systemic disease.
5.Previous exercise treatment for back pain within 3 months.
6.Women having red flag signs like bowel, bladder dysfunction and paresthesia. |
|
|
Method of Generating Random Sequence
|
Stratified randomization |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
| Low back pain, Quality of life, Range of Motion, Radiating symptoms |
Measured on baseline and after 4 weeks |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| Age, Gestation period, Weight |
Pre intervention |
|
|
Target Sample Size
|
Total Sample Size="66" Sample Size from India="66"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
15/03/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1" Months="0" Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
During pregnancy, many women experience back pain and pain that spreads to one or both legs. This happens because of weight gain, posture changes, hormonal changes, and pressure on nerves. These problems can affect daily activities and quality of life. Neural mobilization is a gentle treatment that helps nerves move properly, reduces pain, improves flexibility, and increases blood flow to the nerve. Many previous studies have shown that this technique helps in different nerve-related conditions, but very little research has been done specifically on pregnant women with leg radiating pain.In this study 66 pregnant women will included and they will be divided into three groups, group A will recieve neural mobilization + conventional exercis, group B will recieve conventional exercises + sham treatment and group C will recieve conventional exercises only. Intervention will be given for 3 days per week for 4 weeks. Pain, quality of life, range of motion, and radiating symptoms will be measured before and after treatment. The study expects that women who receive neural mobilization along with exercises will have more pain relief, better movement, and improved quality of life compared to other groups. |