The World Health Organization (WHO) has introduced a global strategy to eliminate cervical cancer, setting the 90–70–90 targets to be reached by 2030.(1) However, several challenges continue to slow this progress, including inadequate access to screening services, limited awareness about HPV and its vaccination, and the hesitation many women feel toward invasive sample collection procedures. Against this backdrop, the proposed study assumes considerable importance. By examining HPV detection in both cervical swabs and urine samples, the study seeks to explore a screening alternative that is less invasive and potentially more acceptable to women, thereby supporting broader participation in screening initiatives. The inclusion of a questionnaire to evaluate knowledge, awareness, and attitudes related to HPV infection, HPV-related cancers, and HPV vaccination among women of reproductive age is expected to shed light on prevailing knowledge gap. Additionally, correlating Pap smear cytology findings with virological HPV test results will enhance the clinical significance of the research. Together, these components support the development of accessible, evidence-based screening strategies, directly contributing to WHO elimination goals and strengthening cervical cancer prevention efforts in the current public health trend.