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CTRI Number  CTRI/2026/04/107529 [Registered on: 02/04/2026] Trial Registered Prospectively
Last Modified On: 31/03/2026
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Drug
Ayurveda 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   To check the effect of medicines Tablet Erandadi Guggulu over Tablet Rasanadi Guggulu along with Ksheera Bala Taila Pratimarsha Nasya as nasal drops in the Management of Apabahuka with special reference to Frozen Shoulder 
Scientific Title of Study   “A Randomized Comparative Clinical Trial to Assess the Efficacy of Erandadi Guggulu over Rasanadi Guggulu in Combination with Ksheerabala Taila Pratimarsha Nasya in the Management of Avabahuka with Special Reference to Frozen Shoulder” 
Trial Acronym  ERK 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  DR KRUTI PATIL 
Designation  Pg scholar 
Affiliation  BVVS Ayurved Medical College and Hospital 
Address  Department of PG Studies in Kayachikitsa BVVS Ayurved Medical College and Hospital, Bagalkot, Karnataka 587101 Bagalkot KARNATAKA 587101 India

Bagalkot
KARNATAKA
587101
India 
Phone  7022847877  
Fax    
Email  patilkruti82@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr sunil kumar M Chabanur  
Designation  Professor and HOD  
Affiliation  BVVS Ayurved Medical College and Hospital 
Address  Department of PG Studies in Kayachikitsa BVVS Ayurved Medical College and Hospital, Bagalkot, Karnataka 587101 Bagalkot KARNATAKA 587101 India

Bagalkot
KARNATAKA
587101
India 
Phone  9740878703  
Fax    
Email  drsunilkumar09@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Dr sunil kumar M Chabanur  
Designation  Professor and HOD  
Affiliation  BVVS Ayurved Medical College and Hospital 
Address  Department of PG Studies in Kayachikitsa BVVS Ayurved Medical College and Hospital, Bagalkot, Karnataka 587101 Bagalkot KARNATAKA 587101 India


KARNATAKA
587101
India 
Phone  9740878703  
Fax    
Email  drsunilkumar09@gmail.com  
 
Source of Monetary or Material Support  
BVVS Ayurved Medical College and Hospital Bagalkot, Karnataka 587101  
 
Primary Sponsor  
Name  BVVS Ayurved Medical College and Hospital  
Address  BVVS Ayurved Medical College and Hospital, Bagalkot, Karnataka 587101  
Type of Sponsor  Private medical college 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
DR KRUTI PATIL  BVVS Ayurved Medical College and Hospital  Department of PG Studies in Kayachikitsa BVVS Ayurved Medical College and Hospital, Bagalkot, Karnataka 587101 Bagalkot KARNATAKA 587101 India
Bagalkot
KARNATAKA 
07022847877

patilkruti82@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
IECBVVSAyurvedMedicalCollegeandHospital BagalkotKarnataka   Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition:M258||Other specified joint disorders. Ayurveda Condition: AVABAHUKAH,  
 
Intervention / Comparator Agent  
snoIntervention/ComparatorTypeDrug-TypeProcedure NameDetails
1Intervention ArmProcedure-nasyam/ nastam, नस्यम्/ नस्तम् (Procedure Reference: Taila kalpana of Sahasrayoga., Procedure details: 1. Poorva Karma Patient should be in the supine position. Patient should avoid Vega Dharana. 2. Pradhana Karma Head is bent backwards for about 450 Elevate the tip of patient’s nose with left thumb and instil 2 drops of Ksheera Bala Taila from dropper in each nostril one after the other. Ask the patient to inhale gently(not forcefully) till the medicine to reach the throat. Duration 30 days 3. Paschat Karma Advise the patient to lie down in the same position till the medicine reaches the throat Gandusha with Ushna Jala. )
(1) Medicine Name: Erandadi Guggulu ., Reference: Vangasena Samhita – Vatavyadhi Chikitsa, Route: Oral, Dosage Form: Guggulu, Dose: 500(mg), Frequency: bd, Duration: 30 Days
2Comparator ArmProcedure-nasyam/ nastam, नस्यम्/ नस्तम् (Procedure Reference: Sahasrayogam- Taila kalpana Adhyāya, Procedure details: 1. Poorva Karma Patient should be in the supine position. Patient should avoid Vega Dharana. 2. Pradhana Karma Head is bent backwards for about 450 Elevate the tip of patient’s nose with left thumb and instil 2 drops of Ksheera Bala Taila from dropper in each nostril one after the other. Ask the patient to inhale gently(not forcefully) till the medicine to reach the throat. 3. Paschat Karma Advise the patient to lie down in the same position till the medicine reaches the throat Gandusha with Ushna Jala. duration 30 days)
(1) Medicine Name: Rasanadi guggulu, Reference: Yogaratnakara- Vatavyadhi Chikitsa, Route: Oral, Dosage Form: Guggulu, Dose: 500(mg), Frequency: bd, Duration: 30 Days
 
Inclusion Criteria  
Age From  20.00 Year(s)
Age To  60.00 Year(s)
Gender  Both 
Details  Patient presenting with classical signs and symptoms of Apabahuka.
Patients of either sex within the age group of 20 -60 years.  
 
ExclusionCriteria 
Details  Fractures, dislocation and traumatic injuries of Shoulder Joint.
Pregnancy and lactation. 
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   On-site computer system 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
To know the efficacy of Erandadi Guggulu over Rasanadi Guggulu along with Ksheera Bala Taila
Pratimarsha Nasya in the Management of Apabahuka with special
reference to Frozen Shoulder 
30 DAYS 
 
Secondary Outcome  
Outcome  TimePoints 
1. To assess the effect of Erandadi Guggulu along with Ksheerabala Taila Pratimarsha
Nasya in the management of Apabahuka with special reference to Frozen Shoulder.
2. To assess the effect of Rasnadi Guggulu along with Ksheerabala Taila Pratimarsha
Nasya in the management of Apabahuka with special reference to Frozen Shoulder.
3. To compare the effect of Erandadi Guggulu over Rasanadi Guggulu along with
Ksheera Bala Taila Pratimarsha Nasya in the Management of Apabahuka with
special reference to Frozen Shoulder. 
30 DAYS 
 
Target Sample Size   Total Sample Size="40"
Sample Size from India="40" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   Phase 2 
Date of First Enrollment (India)   15/04/2026 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  
Apabahuka is one among the Vataja Nanatmaja Vyadhis a condition that hampers 
the normal functioning of the upper limbs thereby significantly affecting an individuals daily 
life It is primarily caused by the vitiation of Vyana Vata which localizes in the Amsa 
Pradesha shoulder region This leads to the Shoshana degeneration of Shleshaka Kapha
Mamsa muscle tissue Sira vessels and Snayu ligaments resulting in symptoms such as 
restricted shoulder movements Bahupraspanditaharatwam pain Shoola and stiffness 
Stambha These symptoms closely resemble those observed in Frozen Shoulder This 
condition is recognized in the modern medical system 
Frozen Shoulder is described as an idiopathic disorder that manifests with painful 
stiffness and progressive restriction of both active and passive shoulder movements despite 
normal radiographic findings of the glenohumeral joint This condition impacts basic 
functional activities such as eating dressing maintaining hygiene and working thus severely 
impairing the patients quality of life The prevalence in the general population is around 3
5per but it increases up to 20per in diabetic individuals Frozen shoulder most commonly 
affects individuals between 40 60 years of age and is observed more frequently in females 
Contemporary management typically involves the use of analgesics intra articular 
corticosteroid injections and physiotherapy However these interventions often provide only 
temporary symptomatic relief 
In contrast Ayurvedic texts offer a more holistic line of treatment for Apabahuka 
including NasyaUttarabhaktika Snehapana Swedana and Shamanoushadhis Among 
these Nasya will help in strengthening the Skanda shoulder and Greeva neck 
Ksheerabala Taila as referenced in Sahasrayogam is a classical formulation widely used for  
Nasya for the management of Vata disorders especially neuromuscular conditions due to its 
Snehana and Brmhana properties with key ingredients including Bala Sida cordifolia 
Ksheera milk and Tila Taila sesame oil
Erandadi Guggulu as referenced in Vangasena Samhita under Vatavyadhi Chikitsa 
is a classical Ayurvedic formulation commonly used in the management of Vata disorders 
affecting the joints and musculoskeletal system particularly conditions involving pain
stiffness and restricted mobility such as Apabahuka frozen shoulder It contains key 
ingredients including Erandamoola Panchakola Raktapunarnava Shwetapunarnava Bala 
Devadaru Haritaki Vidanga Gokshura Guduchi Sahacara Katuki Shati Bruhati 
Kantakari Visagra Ashwagandha Shatavari Vasa Dhaynaka Aragvadha Vruddhadaru 
Ajamoda Haridra Daruharidra Guggulu which collectively exhibit Vatakaphahara 
Shoolahara Shothahara Amapachana and Srotoshodhana properties
Additionally Rasnadi Guggulu found in Yogaratnakaras Vatavyadhiadhikara
comprises potent herbs like Rasna Guduchi Eranda Devadaru Shunthi and Guggulu
These have Ushna Virya and function as Deepana Pachana Vatakaphanashaka 
Shoolahara Shothahara and Balya Through these GunaKarmas the selected 
formulations may help in achieving Samprapti Vighatana of Apabahuka 
Thus this study aims to assess A Randomized Comparative Clinical Study to 
Evaluate the  Efficacy of Erandadi Guggulu over Rasanadi Guggulu along with Ksheera 
Bala Taila Pratimarsha Nasya in the Management of Apabahuka with special reference to 
Frozen
 
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