| CTRI Number |
CTRI/2026/02/104965 [Registered on: 26/02/2026] Trial Registered Prospectively |
| Last Modified On: |
25/02/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Drug
Ayurveda |
| Study Design |
Randomized, Parallel Group, Multiple Arm Trial |
|
Public Title of Study
|
A randomized double arm comparative study on vamana karma at two different purvahna kala followed by pratimarsha nasya in participants with darunaka (pityriasis captitis) |
|
Scientific Title of Study
|
A randomized double arm comparative clinical study on vamana karma in two different purvahna kaala followed by pratimarsha nasya in darunaka with special emphasis on pytriasis captitis (dandruff). |
| Trial Acronym |
nil |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Sanjota Shirashyad |
| Designation |
BAMS |
| Affiliation |
Ayurveda mahavidyalaya hubli |
| Address |
OPD no 2
Department of panchakarma
Ayurveda mahavidyalaya heggeri extension old hubli hubli
108 blue bells apartment hosa road bangalore
Dharwad
KARNATAKA
580024
India |
| Phone |
9740321861 |
| Fax |
|
| Email |
sanjuhulk77@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Padmavati Venkatesh |
| Designation |
Professor |
| Affiliation |
Ayurveda mahavidyalaya hubli |
| Address |
OPD no 2
Department of panchakarma
Ayurveda mahavidyalaya heggeri extension old hubli hubli
Ayurveda mahavidyalaya heggeri extension old hubli hubli
Dharwad
KARNATAKA
580024
India |
| Phone |
9740321861 |
| Fax |
|
| Email |
padmavatikulkarni203@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Dr Padmavati Venkatesh |
| Designation |
Professor |
| Affiliation |
Ayurveda mahavidyalaya hubli |
| Address |
OPD no 2
Department of panchakarma
Ayurveda mahavidyalaya heggeri extension old hubli hubli
Ayurveda mahavidyalaya heggeri extension old hubli hubli
Dharwad
KARNATAKA
580024
India |
| Phone |
9740321861 |
| Fax |
|
| Email |
padmavatikulkarni203@gmail.com |
|
|
Source of Monetary or Material Support
|
|
|
Primary Sponsor
|
| Name |
Dr Sanjota Shirashyad |
| Address |
108 bluebells aprartment erappa reddy layout hosa road bangalore 560100 |
| Type of Sponsor |
Other [self] |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Sanjota Shirashyad |
Ayurveda mahavidyalaya hubli |
OPD no 2
Department of panchakarma
Ayurveda mahavidyalaya heggeri extension old hubli hubli
Dharwad
KARNATAKA |
9740321861
sanjuhulk77@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional ethical committee ayurveda mahavidyalaya hubli |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition:L210||Seborrhea capitis. Ayurveda Condition: DARUNAKAH, |
|
|
Intervention / Comparator Agent
|
| sno | Intervention/Comparator | Type | Drug-Type | Procedure Name | Details | | 1 | Intervention Arm | Procedure | - | vamana-karma/ pracCardanam, वमन-कर्म/ प्रच्छर्दनम् | (Procedure Reference: Ashtanga sangraha Sutrasthana Vamana verechana vidhi adhyaya in kapala roga, Procedure details: Sarvang abhyanga with murchita tila taila followed by bashpa sweda with dashamoola kwatha Mangalacharan & yavagusevana
Akanthapana with ksheera, takra, ikshurasa (any of the one)
Administration of madanaphaladi yoga based on the roga & rogi bala at 6am
Yasthimadhu phanta, saindhava lavana jala, Sukhoshna jala are used as vamanopaga dravya ))
| | 2 | Comparator Arm | Procedure | - | vamana-karma/ pracCardanam, वमन-कर्म/ प्रच्छर्दनम् | (Procedure Reference: Ashtanga sangraha Sutrasthana Vamana verechana vidhi adhyaya in kapala roga, Procedure details: Sarvang abhyanga with murchita tila taila followed by bashpa sweda with dashamoola kwatha Mangalacharan & yvavagusevana
Akanthapana with ksheera, takra, ikshurasa (any of the one)
Administration of madanaphaladi yoga based on the roga & rogi bala at 8am
Yasthimadhu phanta, saindhava lavana jala, Sukhoshna jala are used as vamanopaga dravya ))
|
|
|
|
Inclusion Criteria
|
| Age From |
16.00 Year(s) |
| Age To |
48.00 Year(s) |
| Gender |
Both |
| Details |
Subjects with the signs and symptoms of darunaka ptyriasis captitis
subjects of age group 16 to 48 years of irrespective gender will be included
Minimum duration of dandruff symptoms more than or equal to 1 month
Subjects fit fro vamana karma and nasya karma |
|
| ExclusionCriteria |
| Details |
Scalp psoriasis
Subjects with other systemic and metabolic disorders
Pregnant women and lactating mothers
Subjects with co morbidities and life threatening disease that interfere with the intervention |
|
|
Method of Generating Random Sequence
|
Computer generated randomization |
|
Method of Concealment
|
On-site computer system |
|
Blinding/Masking
|
Open Label |
|
Primary Outcome
|
| Outcome |
TimePoints |
| To determine whether vamana karma performed at 6 am is more effective than vamama karma performed at 8 am in managing darunaka |
4 weeks |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| To access the reduction in shirokandu rukshata twakeshksphutana keshyachuti swapa adherent scalp flaking score |
4 weeks |
|
|
Target Sample Size
|
Total Sample Size="40"
Sample Size from India="40"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
10/03/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="0"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Yet Recruiting |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Darunaka correlated with pityriasis capitis is a common scalp disorder characterized by itching dryness scaling and hair fall it is described in ayurveda under kshudra roga shiro roga and kapalagata roga primarily involving vata kapha dosha imbalance. Modern treatments mainly provide temporary symptomatic relief with frequent recurrence since darunaka predominantly involves kapha in the urdhwajatru region vamana karma therapeutic emesis is indicated as a shodhana therapy to eliminate vitiated Doshas and restore balance Classical texts recommend performing Vamana in purvahna Kaala that is morning time This study aims to compare the efficacy of vamana performed at two different morning timings 6 am and 8 am followed by pratimarsha nasya with bhringaraja taila in managing darunaka the objective is to determine whether the timing of vamana influences therapeutic outcome and to evaluate the combined effect of shodhana and nasya in reducing dandruff symptoms Hence this study aims to assess a classical shodhana approach for better and sustained results Sample size with 40 patients group a vamana at 6 am and group b vamana at 8 am both group receive pratimarsha nasya with bringaraja taila for 21 days after vamana
|