| CTRI Number |
CTRI/2025/11/098118 [Registered on: 26/11/2025] Trial Registered Prospectively |
| Last Modified On: |
24/11/2025 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Drug
Ayurveda |
| Study Design |
Randomized, Parallel Group, Active Controlled Trial |
|
Public Title of Study
|
A randomized comparative clinical study to evaluate the ropana effect of chandanadi taila and samangadi taila in sadyo vrana with special referance to 2nd degree abrasion wound. |
|
Scientific Title of Study
|
A randomized comparative clinical study to evaluate the ropana effect of chandanadi taila and samangadi taila in sadyo vrana with special referance to 2nd degree abrasion wound. |
| Trial Acronym |
Nil |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Subhendu Bikash sahu |
| Designation |
HOD and Professor Department of shalya tantra |
| Affiliation |
Jeevan jyoti ayurvedic medical College and hospital |
| Address |
Jeevan Jyoti Ayurvedic Medical College and Hospital 10th km mile stone Khair road Lodha Aligarh Uttar Pradesh 202140 India
Jeevan Jyoti Ayurvedic Medical College and Hospital 10th km mile stone Khair road Lodha Aligarh Uttar Pradesh 202140 India
Aligarh
UTTAR PRADESH
202140
India |
| Phone |
7978431948 |
| Fax |
05712213536 |
| Email |
vd.kunu2@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Subhendu Bikash sahu |
| Designation |
HOD and Professor Department of shalya tantra |
| Affiliation |
Jeevan jyoti ayurvedic medical College and hospital |
| Address |
Jeevan Jyoti Ayurvedic Medical College and Hospital 10th km mile stone Khair road Lodha Aligarh Uttar Pradesh 202140 India
Jeevan Jyoti Ayurvedic Medical College and Hospital 10th km mile stone Khair road Lodha Aligarh Uttar Pradesh 202140 India
Aligarh
UTTAR PRADESH
202140
India |
| Phone |
7978431948 |
| Fax |
05712213536 |
| Email |
vd.kunu2@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Dr Subhendu Bikash sahu |
| Designation |
HOD and Professor Department of shalya tantra |
| Affiliation |
Jeevan jyoti ayurvedic medical College and hospital |
| Address |
Jeevan Jyoti Ayurvedic Medical College and Hospital 10th km mile stone Khair road Lodha Aligarh Uttar Pradesh 202140 India
Jeevan Jyoti Ayurvedic Medical College and Hospital 10th km mile stone Khair road Lodha Aligarh Uttar Pradesh 202140 India
Aligarh
UTTAR PRADESH
202140
India |
| Phone |
7978431948 |
| Fax |
05712213536 |
| Email |
vd.kunu2@gmail.com |
|
|
Source of Monetary or Material Support
|
| Jeevan jyoti ayurvedic medical College and hospital 10th km mile stone Khair road Lodha Aligarh Uttar Pradesh 202140 India |
|
|
Primary Sponsor
|
| Name |
Dr Ishika Patil |
| Address |
Jeevan Jyoti Ayurvedic Medical College and Hospital 10th km mile stone Khair road Lodha Aligarh Uttar Pradesh 202140 India |
| Type of Sponsor |
Private medical college |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Ishika Patil |
Jeevan jyoti ayurvedic medical College and hospital |
Room no. 303 third floor
10 km mile stone khair road lodha
Aligarh
UTTAR PRADESH |
86020 57964
05712213536
ishikapatil513@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional ethics committee |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition:L989||Disorder of the skin and subcutaneous tissue, unspecified. Ayurveda Condition: SADYOVRANAH, |
|
|
Intervention / Comparator Agent
|
| sno | Intervention/Comparator | Type | Drug-Type | Procedure Name | Details | | 1 | Comparator Arm | Procedure | - | tailam, तैलम् | (Procedure Reference: Sushruta samhita , Procedure details: Local application on affected area once daily for 8 months)
(1) Medicine Name: Chandanadi taila, Reference: Sushruta samhita chikitsa sthana 2/, Route: Topical, Dosage Form: , Dose: 10(ml), Frequency: od, Duration: 8 Days | | 2 | Intervention Arm | Procedure | - | tailam, तैलम् | (Procedure Reference: Sushruta samhita , Procedure details: Local application on affected area once daily for 8 days)
(1) Medicine Name: Samangadi taila, Reference: Sushruta samhita chikitsa sthana 2, Route: Topical, Dosage Form: Taila, Dose: 10(ml), Frequency: od, Duration: 8 Days |
|
|
|
Inclusion Criteria
|
| Age From |
10.00 Year(s) |
| Age To |
40.00 Year(s) |
| Gender |
Both |
| Details |
a)Patients with classical Lakshana of Sadyo (Ghrusta) Vrana (2nd degree abrasion
wound) of duration less the 6 hour with irrespective of sex.
b)Patient having Sadyo vrana related to twaka only and having size maximum Length:
3 cms and maximum width: 3cms.
c)Patients of age group 10-40 years. |
|
| ExclusionCriteria |
| Details |
Patients having allergic rashes over wound site.
b)Patients having DM.
c)Patients having wound in Marma sthana.
d)Patients of HIV, HbsAg etc.
|
|
|
Method of Generating Random Sequence
|
Coin toss, Lottery, toss of dice, shuffling cards etc |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Open Label |
|
Primary Outcome
|
| Outcome |
TimePoints |
| To evaluate the Ropana efficacy of Chandanadi Taila in management of Sadyo (Ghrusta) Vrana with special reference to 2nd degree Abrasion wound. |
Seventh day of trial |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| To evaluate the ropana effect of samngadi taila in sadyovrana |
Seventh day of trial |
|
|
Target Sample Size
|
Total Sample Size="60"
Sample Size from India="60"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
07/12/2025 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="0"
Months="3"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
In the present study, the ropana effect of chandanadi and samangadi taila will be seen as both chandana and samanga works on Rakta dhatu ( act as blood purifiying agent), kushthagna in nature and having anti inflammatory properties.Both drugs brightens the skin and reduces blemishes. |