| CTRI Number |
CTRI/2026/01/100840 [Registered on: 12/01/2026] Trial Registered Prospectively |
| Last Modified On: |
12/01/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Surgical/Anesthesia |
| Study Design |
Randomized, Parallel Group Trial |
|
Public Title of Study
|
A study comparing ultrasound guided cannulation of two different arteries in adult patients |
|
Scientific Title of Study
|
Comparison of ultrasound guided cannulation of first dorsal metatarsal artery versus posterior tibial artery in adult patients: A randomised controlled trial |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Abhiram KT |
| Designation |
Junior Resident |
| Affiliation |
All India Institute of Medical Sciences, Jodhpur |
| Address |
Department of Anaesthesiology and Critical Care,All India Institute of
Medical Sciences (AIIMS), Marudhar Industrial Area Phase-II, Basni,
Jodhpur
Jodhpur
RAJASTHAN
342005
India
Jodhpur RAJASTHAN 342005 India |
| Phone |
7012047708 |
| Fax |
|
| Email |
kt.abhiram3@gmail.com |
|
Details of Contact Person Scientific Query
|
| Name |
Manbir Kaur |
| Designation |
Associate Professor |
| Affiliation |
All India Institute of Medical Sciences, Jodhpur |
| Address |
Department of Anaesthesiology and Critical Care,All India Institute of
Medical Sciences (AIIMS), Marudhar Industrial Area Phase-II, Basni,
Jodhpur
Jodhpur
RAJASTHAN
342005
India
Jodhpur RAJASTHAN 342005 India |
| Phone |
9079864277 |
| Fax |
|
| Email |
doctor.manbir@gmail.com |
|
Details of Contact Person Public Query
|
| Name |
Abhiram KT |
| Designation |
Junior Resident |
| Affiliation |
All India Institute of Medical Sciences, Jodhpur |
| Address |
Department of Anaesthesiology and Critical Care,All India Institute of
Medical Sciences (AIIMS), Marudhar Industrial Area Phase-II, Basni,
Jodhpur
Jodhpur
RAJASTHAN
342005
India
Jodhpur RAJASTHAN 342005 India |
| Phone |
7012047708 |
| Fax |
|
| Email |
kt.abhiram3@gmail.com |
|
|
Source of Monetary or Material Support
|
| All India Institute of Medical Sciences (AIIMS), Basni Industrial Area Phase-II, Jodhpur,Rajasthan
(INDIA) 342005 |
|
|
Primary Sponsor
|
| Name |
All India Institute of Medical Sciences, Jodhpur |
| Address |
Basni Industrial Area Phase II, Jodhpur, Rajasthan (INDIA) 342005 |
| Type of Sponsor |
Research institution and hospital |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Manbir Kaur |
AIIMS JODHPUR |
Department of
Anaesthesiology and
Critical Care, 3rd Floor,
DnT Block, AIIMS,
Basni Industrial Area
Phase-II, Jodhpur-
342005
Jodhpur
RAJASTHAN Jodhpur RAJASTHAN |
9079864277
doctor.manbir@gmaily.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional Ethics Committee(Clinical Trial) AIIMS Jodhpur |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Healthy Human Volunteers |
Patients aged 18 years old or older Belonging to American Society of Anesthesiologists Physical Status 1-3 Belonging to either sex Undergoing elective surgeries and Requiring arterial cannulation
|
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Intervention |
Ultrasound guided first dorsal metatarsal artery cannulation |
Ultrasound guided arterial cannulation of the first dorsal metatarsal artery using short axis out of plane technique under aseptic precautions in adult patients undergoing elective surgery. |
| Comparator Agent |
Ultrasound guided posterior tibial artery cannulation |
Ultrasound guided arterial cannulation of the posterior tibial artery using short axis out of plane technique under aseptic precautions in adult patients undergoing elective surgery. |
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
75.00 Year(s) |
| Gender |
Both |
| Details |
Adult patients aged 18 years or older, belonging to either sex, American Society of Anesthesiologists physical status I to III, undergoing elective surgeries and requiring arterial cannulation. |
|
| ExclusionCriteria |
| Details |
Patients having infection at the access site, patients with coagulopathy or on anticoagulation therapy, patients with pedal edema, and patients with peripheral vascular disease. |
|
|
Method of Generating Random Sequence
|
Computer generated randomization |
|
Method of Concealment
|
Sequentially numbered, sealed, opaque envelopes |
|
Blinding/Masking
|
Open Label |
|
Primary Outcome
|
| Outcome |
TimePoints |
First attempt success rate of arterial cannulation
|
During arterial cannulation
|
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
Number of attempts to cannulate
|
During arterial cannulation
|
Cannulation failure rate
|
During arterial cannulation
|
Total procedure time of arterial cannulation
|
During arterial cannulation
|
Incidence of complications such as ischemia, bleeding, thrombosis and hematoma
|
Intraoperative and immediate postoperative period
|
|
|
Target Sample Size
|
Total Sample Size="234" Sample Size from India="234"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
01/02/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
01/02/2026 |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1" Months="6" Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Yet Recruiting |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Arterial cannulation is commonly required in perioperative settings for continuous blood pressure monitoring and arterial blood gas analysis. The radial artery is most commonly used however alternative sites may be required when radial artery cannulation is not feasible or contraindicated. Posterior tibial artery is an established alternative site. The first dorsal metatarsal artery is another potential site with good collateral circulation but has not been well studied.
This prospective randomized controlled trial aims to compare ultrasound guided cannulation of the first dorsal metatarsal artery versus the posterior tibial artery in adult patients undergoing elective surgeries. Adult patients aged eighteen years or older requiring arterial cannulation will be randomized into two groups. One group will undergo ultrasound guided first dorsal metatarsal artery cannulation and the other group will undergo ultrasound guided posterior tibial artery cannulation.
The primary outcome is first attempt success rate of arterial cannulation. Secondary outcomes include number of attempts to cannulate cannulation failure rate total procedure time and incidence of complications such as ischemia bleeding thrombosis and hematoma. The study aims to evaluate whether first dorsal metatarsal artery can be a reliable alternative to posterior tibial artery for arterial cannulation in adult patients. |