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CTRI Number  CTRI/2026/01/100840 [Registered on: 12/01/2026] Trial Registered Prospectively
Last Modified On: 12/01/2026
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Surgical/Anesthesia 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   A study comparing ultrasound guided cannulation of two different arteries in adult patients 
Scientific Title of Study   Comparison of ultrasound guided cannulation of first dorsal metatarsal artery versus posterior tibial artery in adult patients: A randomised controlled trial 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Abhiram KT 
Designation  Junior Resident  
Affiliation  All India Institute of Medical Sciences, Jodhpur 
Address  Department of Anaesthesiology and Critical Care,All India Institute of Medical Sciences (AIIMS), Marudhar Industrial Area Phase-II, Basni, Jodhpur Jodhpur RAJASTHAN 342005 India

Jodhpur
RAJASTHAN
342005
India 
Phone  7012047708  
Fax    
Email  kt.abhiram3@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Manbir Kaur 
Designation  Associate Professor 
Affiliation  All India Institute of Medical Sciences, Jodhpur 
Address  Department of Anaesthesiology and Critical Care,All India Institute of Medical Sciences (AIIMS), Marudhar Industrial Area Phase-II, Basni, Jodhpur Jodhpur RAJASTHAN 342005 India

Jodhpur
RAJASTHAN
342005
India 
Phone  9079864277  
Fax    
Email  doctor.manbir@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Abhiram KT 
Designation  Junior Resident  
Affiliation  All India Institute of Medical Sciences, Jodhpur 
Address  Department of Anaesthesiology and Critical Care,All India Institute of Medical Sciences (AIIMS), Marudhar Industrial Area Phase-II, Basni, Jodhpur Jodhpur RAJASTHAN 342005 India

Jodhpur
RAJASTHAN
342005
India 
Phone  7012047708  
Fax    
Email  kt.abhiram3@gmail.com  
 
Source of Monetary or Material Support  
All India Institute of Medical Sciences (AIIMS), Basni Industrial Area Phase-II, Jodhpur,Rajasthan (INDIA) 342005 
 
Primary Sponsor  
Name  All India Institute of Medical Sciences, Jodhpur 
Address  Basni Industrial Area Phase II, Jodhpur, Rajasthan (INDIA) 342005 
Type of Sponsor  Research institution and hospital 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Manbir Kaur  AIIMS JODHPUR   Department of Anaesthesiology and Critical Care, 3rd Floor, DnT Block, AIIMS, Basni Industrial Area Phase-II, Jodhpur- 342005 Jodhpur RAJASTHAN
Jodhpur
RAJASTHAN 
9079864277

doctor.manbir@gmaily.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethics Committee(Clinical Trial) AIIMS Jodhpur  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Healthy Human Volunteers  Patients aged 18 years old or older Belonging to American Society of Anesthesiologists Physical Status 1-3 Belonging to either sex Undergoing elective surgeries and Requiring arterial cannulation  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Ultrasound guided first dorsal metatarsal artery cannulation  Ultrasound guided arterial cannulation of the first dorsal metatarsal artery using short axis out of plane technique under aseptic precautions in adult patients undergoing elective surgery. 
Comparator Agent  Ultrasound guided posterior tibial artery cannulation  Ultrasound guided arterial cannulation of the posterior tibial artery using short axis out of plane technique under aseptic precautions in adult patients undergoing elective surgery. 
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  75.00 Year(s)
Gender  Both 
Details  Adult patients aged 18 years or older, belonging to either sex, American Society of Anesthesiologists physical status I to III, undergoing elective surgeries and requiring arterial cannulation. 
 
ExclusionCriteria 
Details  Patients having infection at the access site, patients with coagulopathy or on anticoagulation therapy, patients with pedal edema, and patients with peripheral vascular disease. 
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   Sequentially numbered, sealed, opaque envelopes 
Blinding/Masking   Open Label 
Primary Outcome  
Outcome  TimePoints 
First attempt success rate of arterial cannulation
 
During arterial cannulation
 
 
Secondary Outcome  
Outcome  TimePoints 
Number of attempts to cannulate
 
During arterial cannulation
 
Cannulation failure rate
 
During arterial cannulation
 
Total procedure time of arterial cannulation
 
During arterial cannulation
 
Incidence of complications such as ischemia, bleeding, thrombosis and hematoma
 
Intraoperative and immediate postoperative period
 
 
Target Sample Size   Total Sample Size="234"
Sample Size from India="234" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   01/02/2026 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  01/02/2026 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)   Not Yet Recruiting 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  
Arterial cannulation is commonly required in perioperative settings for continuous blood pressure monitoring and arterial blood gas analysis. The radial artery is most commonly used however alternative sites may be required when radial artery cannulation is not feasible or contraindicated. Posterior tibial artery is an established alternative site. The first dorsal metatarsal artery is another potential site with good collateral circulation but has not been well studied.

This prospective randomized controlled trial aims to compare ultrasound guided cannulation of the first dorsal metatarsal artery versus the posterior tibial artery in adult patients undergoing elective surgeries. Adult patients aged eighteen years or older requiring arterial cannulation will be randomized into two groups. One group will undergo ultrasound guided first dorsal metatarsal artery cannulation and the other group will undergo ultrasound guided posterior tibial artery cannulation.

The primary outcome is first attempt success rate of arterial cannulation. Secondary outcomes include number of attempts to cannulate cannulation failure rate total procedure time and incidence of complications such as ischemia bleeding thrombosis and hematoma. The study aims to evaluate whether first dorsal metatarsal artery can be a reliable alternative to posterior tibial artery for arterial cannulation in adult patients.
 
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