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CTRI Number  CTRI/2026/01/102246 [Registered on: 28/01/2026] Trial Registered Prospectively
Last Modified On: 27/01/2026
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Physiotherapy (Not Including YOGA) 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   Effect of Neurodynamic Mobilization Versus Static Stretching on Motor Function Recovery of the Upper Limb in Stroke Patients at a tertiary care hospital. 
Scientific Title of Study   A Randomized Controlled Trial to Compare the Effect of Neurodynamic Mobilization Versus Static Stretching on Motor Function Recovery of the Upper Limb in Stroke Patients at a Tertiary Care Hospital 
Trial Acronym  Nil 
Secondary IDs if Any  
Secondary ID  Identifier 
nil  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Mohammad Arbaz 
Designation  MPT 
Affiliation  Malla Reddy University  
Address  Malla Reddy Hospital Department of Physiotherapy Suraram
Maisammaguda Kompally District Hyderabad 500100 Telangana
Hyderabad
TELANGANA
500055
India 
Phone  8623003669  
Fax    
Email  mohammadarbazpsd@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Mohammad Arbaz 
Designation  MPT 
Affiliation  Malla Reddy University  
Address  Malla Reddy Hospital Department of Physiotherapy Suraram

Hyderabad
TELANGANA
500055
India 
Phone  8623003669  
Fax    
Email  mohammadarbazpsd@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Mohammad Arbaz 
Designation  MPT 
Affiliation  Malla Reddy University  
Address  Malla Reddy Hospital Department of Physiotherapy Suraram

Hyderabad
TELANGANA
500055
India 
Phone  8623003669  
Fax    
Email  mohammadarbazpsd@gmail.com  
 
Source of Monetary or Material Support  
Malla Reddy University Maisammaguda District Hyderabad 500100 Telangana  
 
Primary Sponsor  
Name  Mohammad Arbaz 
Address  momin pura washim road pusad 445204 dist yavatamal Maharashtra India  
Type of Sponsor  Private medical college 
 
Details of Secondary Sponsor  
Name  Address 
nil  nil 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Abdul Majeed   Malla Reddy hospital  suraram hyderabad telangana 500055
Hyderabad
TELANGANA 
9373792590

majeed9373@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional ethics committee MRIMS  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: D699||Hemorrhagic condition, unspecified,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Comparator Agent  NEURODYNAMIC MOBILIZATION  In this we give mobilization of median nerve, radial nerve and ulnar nerve. Sequence for median nerve mobilization Patient Position: Lying supine 1.Shoulder abducted to ~90°-110 2.Shoulder externally rotated 3.Elbow extended 4.Forearm supinated 5.Wrist and fingers extended 6.Side-bend the neck toward the same side (to reduce tension) 7.Glide by moving wrist into flexion while elbow moves into extension, and vice versa. Sequence for radial nerve mobilization Patient Position: Lying supine 1.depression (stabilize shoulder) 2.Elbow extension 3.Shoulder internal rotation 4.Forearm pronation 5.Wrist, thumb, and finger flexion 6.Ulnar deviation of wrist Sliding (Gliding) Technique: Elbow flexion while wrist extended, then alternate to elbow extension with wrist flexed. Sequence for ulnar nerve mobilization Patient Position: supine 1.Scapular depression 2.Shoulder abduction (~90–110°) 3.Elbow flexion 4.Forearm supination 5.Wrist extension & radial deviation 6.Finger extension 7.Shoulder external rotation 7.Lateral neck flexion Ulnar Nerve Gliding (Sliding): Elbow flexion with wrist extension. Then alternate to elbow extension with wrist flexion. Hold: 3–5 seconds Repetitions: 5–10 reps, 2–3 sets Neurodynamic mobilization techniques (targeting median, ulnar, radial nerves) 20 minutes/session, 5 days/week for 4 weeks. 
Intervention  STATIC STRETCHING  Static stretching for shoulder Crossover Arm Stretch Bring one arm across your chest at shoulder height, keep it straight. Use the opposite hand to gently pull the elbow toward your body. Hold for ~30 seconds. Repeat 2–4 per side. Passive Internal & External Rotation Hold a stick (or broom) behind your back with both hands. For internal rotation: pull the stick horizontally to rotate the upper arm inward; hold 30s . For external rotation: reverse the push—rotate outward; hold 30s . Doorway Chest/Front shoulder Stretch Stand in a doorway, arms bent at goal post (90°), press forearms into doorframe. Lean forward until you feel a stretch across the chest and front of shoulders; hold ~30s. For elbow Passive Extension Rest your elbow on a towel or surface, use your opposite hand (or weight/ cans) to let gravity straighten the elbow fully. Hold ~15-30 sec and gently release; repeat 3–4. Passive Flexion For hand Wrist Extension Stretch Extend your arm straight, palm down. Use the other hand to bend the wrist upward (fingers pointing to ceiling) and hold for 15-30s. Wrist Flexion Stretch Extend forearm, palm up. Bend wrist downward with the opposite hand and hold ~15-30s. Thumb & Finger Mobility Movements Cross thumb to middle finger, spread fingers apart, make a fist then extend. Static stretching of upper limb muscles (shoulder or elbow or wrist) 20 minutes per session 5 days per week for 4 weeks. 
 
Inclusion Criteria  
Age From  40.00 Year(s)
Age To  70.00 Year(s)
Gender  Both 
Details  Diagnosed with ischemic or hemorrhagic stroke within the past 6 months
Upper limb motor impairments (Modified Ashworth Scale equal to two or less than two)
Medically stable 
 
ExclusionCriteria 
Details  Severe cognitive impairments
Upper limb orthopedic conditions
Severe spasticity (Modified Ashworth Scale greater than two)
Participation in other rehabilitation trials 
 
Method of Generating Random Sequence   Coin toss, Lottery, toss of dice, shuffling cards etc 
Method of Concealment   Not Applicable 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
Fugl-Meyer upper extremity scale (FMUE)
Modified Ashworth Scale (MAS) 
1 year 
 
Secondary Outcome  
Outcome  TimePoints 
Universal Goniometry  1 year 
 
Target Sample Size   Total Sample Size="30"
Sample Size from India="30" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   07/02/2026 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary   Stroke is a leading cause of long-term disability. It often leads to upper limb motor impairments that interfere with daily activities and independence. Static stretching is commonly used in rehabilitation to improve muscle flexibility, but it mainly focuses on the musculoskeletal system. Neurodynamic techniques move neural tissues. They might provide extra benefits by addressing neural restrictions that cause motor issues. Even though these techniques are used more often, there is limited evidence comparing the effectiveness of neurodynamic mobilization and static stretching in improving upper limb motor function for stroke patients. This study aims to address that gap by evaluating which method works better. The goal is to help clinicians choose the best rehabilitation strategies to improve motor recovery and functional outcomes for stroke survivors.
Objectives: 
To evaluate the effect of neurodynamic mobilization on upper limb motor function in stroke patients.
To evaluate the effect of static stretching on upper limb motor function in stroke patients.
To compare the effectiveness of neurodynamic mobilization versus static stretching in improving upper limb motor function.
Hypothesis:
Null Hypothesis: There is no significant difference between neurodynamic mobilization and static stretching in improving upper limb motor function in stroke patients.
Alternative Hypothesis: There is a significant difference between neurodynamic mobilization and static stretching in improving upper limb motor function in stroke patients.

A total of 30 stroke patients with upper limb motor impairments will be randomly allocated into two groups: Group A receiving neurodynamic mobilization and Group B receiving static stretching. Both interventions will be administered for 20 minutes per session, 5 days per week, for 4 weeks. Outcomes will focus on improvements in upper limb motor function. The findings of this study are expected to provide evidence-based guidance for physiotherapists in selecting more effective rehabilitation strategies for enhancing upper limb recovery in stroke survivors.
 
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