| CTRI Number |
CTRI/2026/01/102246 [Registered on: 28/01/2026] Trial Registered Prospectively |
| Last Modified On: |
27/01/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Physiotherapy (Not Including YOGA) |
| Study Design |
Randomized, Parallel Group Trial |
|
Public Title of Study
|
Effect of Neurodynamic Mobilization Versus Static Stretching on Motor Function Recovery of the Upper Limb in Stroke Patients at a tertiary care hospital. |
|
Scientific Title of Study
|
A Randomized Controlled Trial to Compare the Effect of Neurodynamic Mobilization Versus Static Stretching on Motor Function Recovery of the Upper Limb in Stroke Patients at a Tertiary Care Hospital |
| Trial Acronym |
Nil |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| nil |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Mohammad Arbaz |
| Designation |
MPT |
| Affiliation |
Malla Reddy University |
| Address |
Malla Reddy Hospital Department of Physiotherapy Suraram Maisammaguda Kompally District
Hyderabad 500100 Telangana
Hyderabad TELANGANA 500055 India |
| Phone |
8623003669 |
| Fax |
|
| Email |
mohammadarbazpsd@gmail.com |
|
Details of Contact Person Scientific Query
|
| Name |
Mohammad Arbaz |
| Designation |
MPT |
| Affiliation |
Malla Reddy University |
| Address |
Malla Reddy Hospital Department of Physiotherapy Suraram
Hyderabad TELANGANA 500055 India |
| Phone |
8623003669 |
| Fax |
|
| Email |
mohammadarbazpsd@gmail.com |
|
Details of Contact Person Public Query
|
| Name |
Mohammad Arbaz |
| Designation |
MPT |
| Affiliation |
Malla Reddy University |
| Address |
Malla Reddy Hospital Department of Physiotherapy Suraram
Hyderabad TELANGANA 500055 India |
| Phone |
8623003669 |
| Fax |
|
| Email |
mohammadarbazpsd@gmail.com |
|
|
Source of Monetary or Material Support
|
| Malla Reddy University Maisammaguda District
Hyderabad 500100 Telangana
|
|
|
Primary Sponsor
|
| Name |
Mohammad Arbaz |
| Address |
momin pura washim road pusad 445204 dist yavatamal Maharashtra India |
| Type of Sponsor |
Private medical college |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Abdul Majeed |
Malla Reddy hospital |
suraram hyderabad telangana 500055 Hyderabad TELANGANA |
9373792590
majeed9373@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional ethics committee MRIMS |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: D699||Hemorrhagic condition, unspecified, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Comparator Agent |
NEURODYNAMIC MOBILIZATION |
In this we give mobilization of median nerve, radial nerve and ulnar nerve. Sequence for median nerve mobilization Patient Position: Lying supine 1.Shoulder abducted to ~90°-110 2.Shoulder externally rotated 3.Elbow extended 4.Forearm supinated 5.Wrist and fingers extended 6.Side-bend the neck toward the same side (to reduce tension) 7.Glide by moving wrist into flexion while elbow moves into extension, and vice versa. Sequence for radial nerve mobilization Patient Position: Lying supine 1.depression (stabilize shoulder) 2.Elbow extension 3.Shoulder internal rotation 4.Forearm pronation 5.Wrist, thumb, and finger flexion 6.Ulnar deviation of wrist Sliding (Gliding) Technique: Elbow flexion while wrist extended, then alternate to elbow extension with wrist flexed. Sequence for ulnar nerve mobilization Patient Position: supine 1.Scapular depression 2.Shoulder abduction (~90–110°) 3.Elbow flexion 4.Forearm supination 5.Wrist extension & radial deviation 6.Finger extension 7.Shoulder external rotation 7.Lateral neck flexion Ulnar Nerve Gliding (Sliding): Elbow flexion with wrist extension. Then alternate to elbow extension with wrist flexion. Hold: 3–5 seconds Repetitions: 5–10 reps, 2–3 sets
Neurodynamic mobilization techniques (targeting median, ulnar, radial nerves) 20 minutes/session, 5 days/week for 4 weeks. |
| Intervention |
STATIC STRETCHING |
Static stretching for shoulder Crossover Arm Stretch Bring one arm across your chest at shoulder height, keep it straight. Use the opposite hand to gently pull the elbow toward your body. Hold for ~30 seconds. Repeat 2–4 per side. Passive Internal & External Rotation Hold a stick (or broom) behind your back with both hands. For internal rotation: pull the stick horizontally to rotate the upper arm inward; hold 30s . For external rotation: reverse the push—rotate outward; hold 30s . Doorway Chest/Front shoulder Stretch Stand in a doorway, arms bent at goal post (90°), press forearms into doorframe. Lean forward until you feel a stretch across the chest and front of shoulders; hold ~30s. For elbow Passive Extension Rest your elbow on a towel or surface, use your opposite hand (or weight/ cans) to let gravity straighten the elbow fully. Hold ~15-30 sec and gently release; repeat 3–4. Passive Flexion For hand Wrist Extension Stretch Extend your arm straight, palm down. Use the other hand to bend the wrist upward (fingers pointing to ceiling) and hold for 15-30s. Wrist Flexion Stretch Extend forearm, palm up. Bend wrist downward with the opposite hand and hold ~15-30s. Thumb & Finger Mobility Movements Cross thumb to middle finger, spread fingers apart, make a fist then extend.
Static stretching of upper limb muscles (shoulder or elbow or wrist) 20 minutes per session 5 days per week for 4 weeks. |
|
|
Inclusion Criteria
|
| Age From |
40.00 Year(s) |
| Age To |
70.00 Year(s) |
| Gender |
Both |
| Details |
Diagnosed with ischemic or hemorrhagic stroke within the past 6 months
Upper limb motor impairments (Modified Ashworth Scale equal to two or less than two)
Medically stable |
|
| ExclusionCriteria |
| Details |
Severe cognitive impairments
Upper limb orthopedic conditions
Severe spasticity (Modified Ashworth Scale greater than two)
Participation in other rehabilitation trials |
|
|
Method of Generating Random Sequence
|
Coin toss, Lottery, toss of dice, shuffling cards etc |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
Fugl-Meyer upper extremity scale (FMUE)
Modified Ashworth Scale (MAS) |
1 year |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| Universal Goniometry |
1 year |
|
|
Target Sample Size
|
Total Sample Size="30" Sample Size from India="30"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
07/02/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1" Months="0" Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Stroke is a leading cause of long-term disability. It often leads to upper limb motor impairments that interfere with daily activities and independence. Static stretching is commonly used in rehabilitation to improve muscle flexibility, but it mainly focuses on the musculoskeletal system. Neurodynamic techniques move neural tissues. They might provide extra benefits by addressing neural restrictions that cause motor issues. Even though these techniques are used more often, there is limited evidence comparing the effectiveness of neurodynamic mobilization and static stretching in improving upper limb motor function for stroke patients. This study aims to address that gap by evaluating which method works better. The goal is to help clinicians choose the best rehabilitation strategies to improve motor recovery and functional outcomes for stroke survivors. Objectives: To evaluate the effect of neurodynamic mobilization on upper limb motor function in stroke patients. To evaluate the effect of static stretching on upper limb motor function in stroke patients. To compare the effectiveness of neurodynamic mobilization versus static stretching in improving upper limb motor function. Hypothesis: Null Hypothesis: There is no significant difference between neurodynamic mobilization and static stretching in improving upper limb motor function in stroke patients. Alternative Hypothesis: There is a significant difference between neurodynamic mobilization and static stretching in improving upper limb motor function in stroke patients.
A total of 30 stroke patients with upper limb motor impairments will be randomly allocated into two groups: Group A receiving neurodynamic mobilization and Group B receiving static stretching. Both interventions will be administered for 20 minutes per session, 5 days per week, for 4 weeks. Outcomes will focus on improvements in upper limb motor function. The findings of this study are expected to provide evidence-based guidance for physiotherapists in selecting more effective rehabilitation strategies for enhancing upper limb recovery in stroke survivors. |