| CTRI Number |
CTRI/2026/01/100589 [Registered on: 08/01/2026] Trial Registered Prospectively |
| Last Modified On: |
24/12/2025 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Drug
Ayurveda
Other (Specify) |
| Study Design |
Single Arm Study |
|
Public Title of Study
|
A clinical study to evaluate the efficacy of Laghumalini vasant rasa in the management of Shweta Pradara with special reference to Abnormal vaginal discharge |
|
Scientific Title of Study
|
A clinical study to evaluate the efficacy of Laghumalini vasant rasa in the management of Shweta pradara w.s.r. Abnormal vaginal discharge |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| nil |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Neelam Gupta |
| Designation |
Prasuti tantra evam stree roga post graduate scholar |
| Affiliation |
Jeevan Jyoti Ayurvedic medical college and hospital |
| Address |
Jeevan Jyoti Ayurvedic medical college and hospital lodha aligarh,UP 202140
Jeevan Jyoti Ayurvedic medical college and hospital lodha aligarh,UP 202140
Aligarh
UTTAR PRADESH
202140
India |
| Phone |
7003181339 |
| Fax |
|
| Email |
ng661349@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Mamata Kumari Swain |
| Designation |
Professor and Head of the Department of Prasuti tantra evam stree roga |
| Affiliation |
Jeevan Jyoti Ayurvedic medical college and hospital aligarh |
| Address |
Jeevan Jyoti Ayurvedic medical college and hospital lodha aligarh,UP 202140
Jeevan Jyoti Ayurvedic medical college and hospital lodha aligarh,UP 202140
Aligarh
UTTAR PRADESH
202140
India |
| Phone |
9348576189 |
| Fax |
|
| Email |
swaindrmamata@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Dr Mamata Kumari Swain |
| Designation |
Professor and Head of the Department of Prasuti tantra evam stree roga |
| Affiliation |
Jeevan Jyoti Ayurvedic medical college and hospital aligarh |
| Address |
Jeevan Jyoti Ayurvedic medical college and hospital lodha aligarh UP 202140
Jeevan Jyoti Ayurvedic medical college and hospital lodha aligarh UP 202140
Aligarh
UTTAR PRADESH
202140
India |
| Phone |
9348576189 |
| Fax |
|
| Email |
swaindrmamata@gmail.com |
|
|
Source of Monetary or Material Support
|
| Department of PG studies in Prasuti tantra evam Stree roga, Jeevan Jyoti Ayurvedic Medical College and Hospital Lodha Aligarh |
|
|
Primary Sponsor
|
| Name |
Jeevan Jyoti Ayurvedic medical college and hospital |
| Address |
Jeevan Jyoti Ayurvedic medical college and hospital, Lodha,Aligarh-202140 |
| Type of Sponsor |
Private medical college |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Neelam Gupta |
Jeevan Jyoti Ayurvedic Medical college and hospital aligarh |
Department of pg studies in Prasuti tantra evam stree roga Jeevan Jyoti Ayurvedic Medical college and hospital , 10th K.M Mile stone , khair road lodha , aligarh -202140
Aligarh
UTTAR PRADESH |
7003181339
ng661349@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional ethics committee |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition:N898||Other specified noninflammatory disorders of vagina. Ayurveda Condition: SOMAROGAH/SVETAPRADARAH, |
|
|
Intervention / Comparator Agent
|
| sno | Intervention/Comparator | Type | Drug-Type | Procedure Name | Details | | 1 | Intervention Arm | Drug | Classical | | (1) Medicine Name: Laghumalini vasanta rasa, Reference: Ayurveda Sara Sangrah, Shri Vaidyanath Ayurveda Bhavan Limited, Naini,Allahabad Edition 2017, Rasa rasayan prakaran Laghumalini Vasant rasa Pg- 447-448., Route: Oral, Dosage Form: Rasayoga, Dose: 250(mg), Frequency: bd, Bhaishajya Kal: Adhobhakta, Duration: 90 Days, anupAna/sahapAna: Yes(details: Milk or ghee), Additional Information: - |
|
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
45.00 Year(s) |
| Gender |
Female |
| Details |
Women aged between 18-45 years.
Patient having excessive whitish vaginal discharge with rule out pruritus along with other
sign and symptoms of Shweta Pradara will be taken for study. |
|
| ExclusionCriteria |
| Details |
Women below 18 years and above 45 years
PID Genital prolapse
Systemic disorders
Patient having metabolic disorders such as DM Hyperthyroidism Hypothyroidism
Patient having blood stained discharge
PATIENTS HAVING BLOOD STAINED DISCHARGE |
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Open Label |
|
Primary Outcome
|
| Outcome |
TimePoints |
| Relief from yoni srava,yoni kandu,kati sula,yoni daha and yoni dourgandha |
3 months |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| Improvement in quality of life reduction in associated symptoms such as Kati shoola, Maithun asahishnuta |
3 months |
|
|
Target Sample Size
|
Total Sample Size="40"
Sample Size from India="40"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
24/01/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="0"
Months="3"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Shweta Pradara is one of the most common problems faced by the women in India. It is not a
disease mentioned as a symptom in various yoni vyapadas.
The word Shweta Pradara has not described in Brihatarayee i.e. Charak samhita, Sushruta
samhita, Ashtanga hridaya & Ashtanga Sangraha. For white vaginal discharge the word Shweta
Pradara has described in Sarangadhara samhita, Bhavaprakash, Yogaratnakar and in
commentry on Charak samhita by Chakrapani.
The commentator of Charak samhita has explained Shweta Pradara as Pandura Pradara.
Shweta Pradara is primarily came by an imbalance of kapha and vata dosha in the body, the
discharge per vagina is white in colour hence it is considered due to kapha prakopa though
kapha dosha involvement is directly not mentioned in ayurveda.
Sushruta and Vagbhatt has also considered kapha as the main dosha responsible for puya and
soph respectively. Acharya Charak has already mentioned that any type of yoni rogas doesn’t
occur without the involvement of vata dosha.
Abnormal vaginal discharge is a frequent complaints of women seen in gynecological clinic it
creates irritation in women’s freedom along with the other symptoms like feeling of weakness,
pain in the back and calves, pruritus on & around the vulva & thigh etc. It may be physiological
hor pathological.
Pathological vaginal discharges are actual symptoms of different disease. Any change in the
Colour, consistency, amount, odour indicates a vaginal infection. Discharges may be present as
purulent, thick, foul smelling, mucoid, blood tinged or watery each suggests a specific
underlying infections Hence, understanding this disease from an Ayurvedic point of view and planning an effective
treatment modality is the need of the hour. Keeping this in view, it is necessary to explore more
appropriate and effective treatments that are relatively more cost-effective without side effects.
Therefore, one such attempt was made to using Laghumalini Vasant Rasa to determine its
efficacy in treating the disease Shweta Pradara.. |