CTRI

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CTRI Number

CTRI/2025/10/095615 [Registered on: 06/10/2025] Trial Registered Prospectively

Last Modified On:

08/05/2026

Post Graduate Thesis

Type of Trial

Interventional

Type of Study

Preventive
Screening
Process of Care Changes
Behavioral

Study Design

Single Arm Study

Public Title of Study

From Stress to Strength: A School-Based Program to Support Adolescents’ Well-Being in India

Scientific Title of Study

A Targeted School-Based Intervention for Adverse Childhood Experiences: Integrating Trauma-Informed Care to Promote Mental Health and Mitigate NCD Risk in Indian Adolescents

Trial Acronym

ACES trial

Secondary IDs if Any

Secondary ID	Identifier
NIL	NIL

Details of Principal Investigator or overall Trial Coordinator (multi-center study)

Name	Bhavneet Bharti
Designation	Director Principal
Affiliation	Dr BR Ambedkar Institute of Medical Sciences , SAS Nagar Punjab
Address	Admin Office of Director Principal College Building Dr BR Ambedkar State Institute of Medical Sciences Mohali SAS Nagar Punjab Admin Office of Director Principal College Building Dr BR Ambedkar State Institute of Medical Sciences Mohali SAS Nagar , Punjab Rupnagar PUNJAB 160055 India
Phone	09914208327
Fax
Email	bhavneetsahul@gmail.com

Details of Contact Person
Scientific Query

Name	Bhavneet Bharti
Designation	Director Principal
Affiliation	Dr BR Ambedkar Institute of Medical Sciences , SAS Nagar Punjab
Address	Admin Office of Director Principal College Building Dr BR Ambdedkar State Institute of Medical Sciences Mohali SAS Nagar , Punjab Admin Office of Director Principal College Building Dr BR Ambdedkar State Institute of Medical Sciences Mohali SAS Nagar , Punjab Chandigarh CHANDIGARH 160055 India
Phone	09914208327
Fax
Email	bhavneetsahul@gmail.com

Details of Contact Person
Public Query

Name	Bhavneet Bharti
Designation	Director Principal
Affiliation	Dr BR Ambedkar Institute of Medical Sciences , SAS Nagar Punjab
Address	Admin Office of Director Principal College Building Dr BR Ambdedkar State Institute of Medical Sciences Mohali SAS Nagar , Punjab Admin Office of Director Principal College Building Dr BR Ambdedkar State Institute of Medical Sciences Mohali SAS Nagar , Punjab Rupnagar PUNJAB 160055 India
Phone	09914208327
Fax
Email	bhavneetsahul@gmail.com

Source of Monetary or Material Support

Indian Council of Medical Research (ICMR) V Ramalingaswami Bhawan Ansari Nagar , New Delhi 110029 India

Primary Sponsor

Name	Indian Council of Medical Research ICMR
Address	Indian Council of Medical Research ICMR V Ramalingaswami Bhawan Ansari Nagar , New Delhi 110029 India
Type of Sponsor	Government funding agency

Details of Secondary Sponsor

Name	Address
NIL	NIL

Countries of Recruitment

India

Sites of Study

No of Sites = 1
Name of Principal Investigator	Name of Site	Site Address	Phone/Fax/Email
Dr Bhavneet Bharti	Dr BR Ambedkar State Institute of Medical Sciences Mohali Punjab	Admin office , College Building Dr BR Ambedkar State Institute of Medical Sciences Mohali, SAS Nagar Rupnagar PUNJAB	09914208327 bhavneetsahul@gmail.com

Details of Ethics Committee

No of Ethics Committees= 1
Name of Committee	Approval Status
Instituitional Ethics Committee-Human Research	Approved

Regulatory Clearance Status from DCGI

Status

Not Applicable

Health Condition / Problems Studied

Health Type	Condition
Healthy Human Volunteers	ACEs

Intervention / Comparator Agent

Type	Name	Details
Intervention	Evidence based Tauma Informed Intervention TIC	Trauma Informed Intervention will be delivered for 8-12 Weeks in children who are screen positive for Adverse childhood experiences ACEs
Comparator Agent	None	If a child with Adverse Childhood experiences is identified , all children will be provided Trauma Informed care . No comparator is there

Inclusion Criteria

Age From	13.00 Year(s)
Age To	18.00 Year(s)
Gender	Both
Details	Students from Public and Private schools of Chandigarh and Mohali (SAS Nagar)Punjab

ExclusionCriteria

Details

nil

Method of Generating Random Sequence

Not Applicable

Method of Concealment

Not Applicable

Blinding/Masking

Not Applicable

Primary Outcome

Outcome	TimePoints
Prevalence of Adverse Childhood Experience (ACEs )among school going adolescents.	Complete Baseline data

Secondary Outcome

Outcome	TimePoints
1.Pattern and distribution of specific ACEs (Adverse Childhood Experiences) categories	Baseline
2.Association between demographic factors and ACEs (Adverse Childhood Experiences )exposure	Baseline
3.Comparison of ACE(Adverse Childhood Experiences) prevalence across different subgroups	Baseline
4.Frequency of co-occuring ACEs ( Adverse Childhood Experiences)	Baseline
5.Identification of high risk groups based on sociodemographic correlates	Baseline
6.Prevalence of Biobehavioral risk factors for Non communicable Diseases ( NCDs) among adolescents	Baseline
Association between ACE scores and mental health status	Baseline
Association between ACE scores and bio-behavioral risk factors	Baseline
Completion of a structured,evidence based TIC intervention module.	1 year
Reduction in emotional and behavioral symtoms,and depressive symptoms	3 years
Improvement in school related functioning	3 years

Target Sample Size

Total Sample Size="1632"
Sample Size from India="1632"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials"

Phase of Trial

N/A

Date of First Enrollment (India)

27/10/2025

Date of Study Completion (India)

Applicable only for Completed/Terminated trials

Date of First Enrollment (Global)

Date Missing

Date of Study Completion (Global)

Applicable only for Completed/Terminated trials

Estimated Duration of Trial

Years="3"
Months="0"
Days="0"

Recruitment Status of Trial (Global)
Modification(s)

Not Yet Recruiting

Recruitment Status of Trial (India)

Open to Recruitment

Publication Details

N/A

Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?

Response - NO

Brief Summary

Rationale/Gaps in Existing Knowledge: Adverse Childhood Experiences (ACEs) significantly predict lifelong mental and physical health outcomes. Despite extensive global evidence, India-specific data remains limited, particularly for adolescents. A comprehensive JAMA meta-analysis (2025) of 65 studies included only one Indian study, highlighting a critical knowledge gap. While Indian adolescents face increasing mental health challenges and academic pressure, evidence-based, culturallyappropriate trauma-informed interventions are notably absent in educational settings. Novelty: This pioneering study in North India integrates Social-Emotional Learning (SEL) with trauma-informed care for adolescents (Classes 8-12) in Mohali and Chandigarh schools. The innovative approach combines capacity building for educators with systematic screening and intervention, aligning with both the National Education Policy (NEP 2020) and National Mental Health Policy (2014). It uniquely addresses the intersection of ACEs, mental health, and early NCD risk factors within the Indian educational context. Objectives: To assess ACE prevalence and patterns among school-going adolescents evaluate associations between ACEs, mental health outcomes, and NCD risk factors and develop, implement, and evaluate a culturally-sensitive, school-based intervention program. Methods: A mixed-methods approach will employ validated ACE questionnaires, mental health assessments, and NCD risk screening tools, complemented by focus group discussions and key informant interviews. A structured 8-12 weeks intervention will be evaluated through pre-post assessments and process documentation. Expected Outcomes: The study will provide region-specific ACE data, establish an evidencebased intervention model, enhance school-based trauma-informed care capacity, and demonstrate improved mental health and NCD risk outcomes among adolescents.