| CTRI Number |
CTRI/2025/12/098868 [Registered on: 11/12/2025] Trial Registered Prospectively |
| Last Modified On: |
10/12/2025 |
| Post Graduate Thesis |
No |
| Type of Trial |
Interventional |
|
Type of Study
|
Surgical/Anesthesia |
| Study Design |
Single Arm Study |
|
Public Title of Study
|
Effect of the FRONT Block for pain relief in Hip Surgery |
|
Scientific Title of Study
|
Safety and Analgesic Effectiveness of the (Femoral Rami and Obturator Nerve Truck) FRONT for Hip Surgery: A Prospective Case Series |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Debesh Bhoi |
| Designation |
Professor |
| Affiliation |
All India Institute Of Medical Sciences, Delhi, India |
| Address |
Department of anesthesia, pain medicine and critical care, Ansari Nagar
AIIMS, Delhi
South
DELHI
110029
India |
| Phone |
09711896795 |
| Fax |
|
| Email |
debeshbhoi@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Debesh Bhoi |
| Designation |
Professor |
| Affiliation |
All India Institute Of Medical Sciences, Delhi, India |
| Address |
Department of anesthesia, pain medicine and critical care, Ansari Nagar
AIIMS, Delhi
DELHI
110029
India |
| Phone |
09711896795 |
| Fax |
|
| Email |
debeshbhoi@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Neha Garg |
| Designation |
Assistant Professor |
| Affiliation |
All India Institute Of Medical Sciences, Delhi, India |
| Address |
Department of anesthesia, pain medicine and critical care, Ansari Nagar
AIIMS, Delhi
New Delhi
DELHI
110029
India |
| Phone |
09711896795 |
| Fax |
|
| Email |
neha.dr.garg@gmail.com |
|
|
Source of Monetary or Material Support
|
| AIIMS, Ansari Nagar,New Delhi , India, 110029 |
|
|
Primary Sponsor
|
| Name |
AIIMS DELHI |
| Address |
AIIMS, New Delhi, India, 110029 |
| Type of Sponsor |
Government medical college |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Debesh Bhoi |
National Centre for aging, AIIMS |
Department of anesthesia, pain medicine and critical care, Ansari Nagar
AIIMS
South
DELHI |
09711896795
debeshbhoi@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| AIIMS INSTITUTIONAL ETHICS COMMITTEE |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: O||Medical and Surgical, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Intervention |
FRONT block |
•Perform FRONT block under ultrasound guidance after giving spinal block before start of surgery.
•Dose used: 10 ml in obturator 0.25 % ropivacaine +20 ml in PENG 0.25 % ropivacaine along with dexamethasone 4 mg one time before the start of procedure
|
| Comparator Agent |
NIL/ NA |
NIL/ NA |
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
99.00 Year(s) |
| Gender |
Both |
| Details |
Age more than 18 years
ASA physical status 1 to 3
Scheduled for elective hip surgery under spinal
Able to provide informed consent
|
|
| ExclusionCriteria |
| Details |
Allergy to local anesthetics
Infection at block site
Coagulopathy or on anticoagulant therapy
Pre-existing neurological deficits in lower limbs
Cognitive impairment or inability to understand pain scoring
• Complex hip surgery like revision THR
|
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
| To assess the analgesic effect of the FRONT block in patients undergoing hip surgery using VAS score till first 24 hours of surgery. |
0, 2, 4, 6, 12, 24, and 48 hours
|
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
• To evaluate fentanyl consumption postoperatively.
• Time to breakthrough pain in hours
• To monitor block-related complications or adverse events (quadriceps weakness etc)
|
0, 2, 4, 6, 12, 24, and 48 hours |
|
|
Target Sample Size
|
Total Sample Size="20"
Sample Size from India="20"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
26/12/2025 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="0"
Months="6"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Open to Recruitment |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Over the past decade,
regional anesthesia techniques have evolved significantly to better target the
sensory innervation of the hip joint while minimizing motor blockade. Among
these, the Pericapsular Nerve Group (PENG) block and the Femoral Rami and Obturator
Nerve Trunk (FRONT) block have emerged as two distinct strategies aimed at
providing effective analgesia for anterior hip procedures. While both blocks
share the objective of targeting articular branches innervating the anterior
hip .A key theoretical advantage of the FRONT block provides
direct and predictable coverage of the obturator nerve, which is a
critical contributor to hip joint innervation but is inconsistently reached by
the PENG block. Moreover, by clearly defining the fascial planes involved, the
FRONT block aims to reduce the variability seen with pericapsular techniques,
offering potentially good analgesic effect for hip surgeries . |