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CTRI Number  CTRI/2025/10/096249 [Registered on: 21/10/2025] Trial Registered Prospectively
Last Modified On: 17/10/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Homeopathy 
Study Design  Other 
Public Title of Study   To study the effectiveness of Homoeopathic Medicine in Fifty Millesimal Potency in The Management fungal infection Among Adults 
Scientific Title of Study   Effectiveness of Individualized Homoeopathic Medicine in Fifty Millesimal Potency in The Management of Tinea Corporis Among Adults an Experimental Non Controlled Study 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Utkarsha Uttam Shingare 
Designation  PG Student  
Affiliation  Dr G D Pol Foundation Y M T Homoeopathic Medical College and PG Institute Hospital 
Address  Out Patient Department No 01 ,Ground floor,Medicine Department ,DR G D Pol Foundation Y M T Homoeopathic Medical College and PG Institute Hospital, Institutional area, Sector 04, Kharghar, Navi Mumbai

Raigarh
MAHARASHTRA
410210
India 
Phone  9834526558  
Fax    
Email  utkarsha00shingare@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  DR Sachin Y Chokakkar 
Designation  Guide And Professor 
Affiliation  Dr G D Pol Foundation Y M T Homoeopathic Medical College and PG Institute Hospital 
Address  Outpatient Department No 01, Medicine Department, DR G D Pol Foundation Y M T Homoeopathic Medical College and PG Institute Hospital, Institutional area, Sector 04, Kharghar, Navi Mumbai

Raigarh
MAHARASHTRA
410210
India 
Phone  9172488888  
Fax    
Email  newbeginingsach@yahoo.com  
 
Details of Contact Person
Public Query
 
Name  DR Sachin Y Chokakkar 
Designation  Guide And Professor 
Affiliation  Dr G D Pol Foundation Y M T Homoeopathic Medical College and PG Institute Hospital 
Address  Out Patient Department no 01,Ground floor ,Medicine Department, DR G D Pol Foundation Y M T Homoeopathic Medical College and PG Institute Hospital, Institutional area, Sector 04, Kharghar, Navi Mumbai

Raigarh
MAHARASHTRA
410210
India 
Phone  9172488888  
Fax    
Email  newbeginingsach@yahoo.com  
 
Source of Monetary or Material Support  
DR G D Pol Foundation Y M T Homoeopathic Medical College and PG Institute Hospital Institutional area sector 04 Kharghar Navi Mumbai , Taluka Panvel,District Raigarh,State Maharashtra ,Country India ,Pin code 410210 
 
Primary Sponsor  
Name  Dr Utkarsha Uttam Shingare 
Address  DR G D Pol Foundation Y M T Homoeopathic Medical College and PG Institute Hospital, Institutional area, Sector 04, Kharghar, Navi Mumbai,Taluka Panvel ,District Raigarh, State Maharashtra ,Country India ,Pincode no 410210 
Type of Sponsor  Other [SELF SPONSORED] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Utkarsha Uttam Shingare  Dr G D Pol Foundation Y M T Homoeopathic Medical College and PG Institute Hospital  Out Patient Department No.01 Ground floor,Medicine Department, DR G D Pol Foundation Y M T Homoeopathic Medical College and PG Institute Hospital, Institutional area, Sector 04, Kharghar, Navi Mumbai pincode 410210
Raigarh
MAHARASHTRA 
9834526558

utkarsha00shingare@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
DR G D Pol Foundation Y M T Homoeopathic Medical College and PG Institute Hospital  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: B354||Tinea corporis,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Homoeopathic management  Homoeopathic management with individualized homoeopathic medicine in fifty millesimal potency 
Comparator Agent  NIL  NIL 
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  64.00 Year(s)
Gender  Both 
Details  Patients of adult age group
Clinically diagnosed patients of Tinea corporis
Patients of all genders
Patients willing to give their free consent  
 
ExclusionCriteria 
Details  Complication of Tinea corporis like secondary bacterial infection,eczema ,Majocchi granuloma
Cases having Tinea corporis infection secondary to Autoimmune disease
Cases of immuno-compromised diseases
Pregnant and lactating female
patients under any line of treatment for Tinea corporis for last3 months
Cases whose pretreatment DASI score is above 41. 
 
Method of Generating Random Sequence   Other 
Method of Concealment   Other 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
Outcome assessment will be done by applying Dermatophytosis Area Severity
Index score
A DASI score of 1 to 15 is Considered Mild disease.
2. A DASI score of 16 to 40 is Considered Moderate disease
3.A DASI score of more than 41 is Consider Severe disease.

 
Duration of study is 18 months.
Duration of each case Each case will be studied for a
period of 6 months or if remission occur, whichever is
earlier.
Duration of Follow up is Each case will be followed up at the interval of 15 days or as and when required.
Clinical assessment will be done at baseline, 3rd month and at the end of the treatment or 6th month, whichever is earlier. 
 
Secondary Outcome  
Outcome  TimePoints 
NOT APPLICABLE  NOT APPLICABLE 
 
Target Sample Size   Total Sample Size="32"
Sample Size from India="32" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   Phase 2 
Date of First Enrollment (India)   30/10/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

TINEA CORPORIS is infection of glabrous skin manifested by well demarcated, annular, pruritic scaly lesion that undergo central clearing. Dermatophyte infection of skin is of is often called ringworm. Tinea the Latin word for worm, describes the serpentine nature of skin lesion. Dermatophyte infections are extremely common and usually caused by fungi of the Microspore, Trichophyton and Epidermophyton species. The fungi can originate from soil (geophilic) or animals (zoophilic), or be canned to human skin, anthropophilic.

  RELEVANT EPIDEMIOLOGICAL DATA, In India, due to tropical environmental conditions, there is higher prevalence of dermatophytosis. The prevalence of tinea has increased since few years due to unhygienic conditions among people living in crowded damp places, patients having systemic clinical conditions like Diabetes mellitus, human immunodeficiency virus, and among patients who irrationally use antifungal Adults are more commonly affected age group. Males are more commonly affected than females. The factor which predisposes for tinea are sweating, obesity, diabetes mellitus, working in places with high temperature, wearing damp clothes in humid weather, sharing personal clothes with infected person.

 EXISTING KNOWLEDGE GAPS AND HOW TO BRIDGE SUCH GAPS, by conducting a well-designed study, uncontrolled, it provides empirical data on whether individualized homeopathy can effectively treat Tinea corporis compared to placebo or conventional antifungals. By assessing long-term outcomes e.g., 3 To 6-month follow-up, study can determine if homeopathy not only treats acute symptoms but also prevents recurrence. Study bridges gaps by, Providing evidence-based validation for individualized homeopathy in dermatomycoses.  Offering a comparative perspective against convectional treatment. And exploring long term benefits and recurrence prevention.

 In Homoeopathy Hahnemann suggest the judicious, sure, efficacious and radical treatment of the local maladies that occurred from little or no injury from without should be directed against the whole by means of internal remedies. Such treatment must affect the annihilation and cure of general malady which caused it to manifest Dr. Hahnemann, in his 6th edition of Organon of medicine, introduced a new method of dynamization of drugs. He termed it as Renewed Dynamization in aphorism 161. In footnote to aphorism 246, he writes, new altered, but perfected method. In section 270, he mentioned about the preparation of potencies, its repetition depending upon the nature of disease, Chronicity of illness etc. The discovery of 50 Millesimal potency by Dr. Samuel Hahnemann was resultant of the quest for a perfect method of potentization, which took around four decades of eventful, valuable efforts. In his words, this method of dynamization the preparations thus produced, I have found after many laborious experiments and counter-experiments, to be the most powerful and at the same time mildest in action, that is, as the most perfected the material part of the medicine is lessened with each degree of dynamization 50,000 times, yet incredibly increased in power.

Homoeopathic medicines are known to rarely produce side effects and are also cost effective and safe in administration Homeopathy has always offered a safe and significant results in controlling the infections of cutaneous disorders, including atopic dermatitis in the present study we have showed the results of homeopathy in dermatophytes infections in various age group affections. Homoeopathy has always been a safe and cost-effective treatment in cases of dermatophyte infections constitutional individualized medicine for such chronic local affections. Hence study will be undertaken to study effectiveness of individualized homoeopathic medicine in the fifty millesimal potency in the management of tinea corporis among adults. This study bridges the gap by assessing the impact of effectiveness of Individualization homoeopathic medicine in fifty millesimal potency in Management of Tinea corporis among adults thus will provide the clinical evidence for its effectiveness.

 Primary objective, To study the Effectiveness of Individualized Homoeopathic Medicine in fifty Millesimal potency in the Management of tinea corporis among adults, up to 6 months or if remission occurs whichever is earlier.

Other objective, To assess the patient pre-treatment and post-treatment scores for tinea corporis among adults prevalidated with  Dermatophytosis Area Severity Index up to 6months or if remission occurs whichever is earlier.

STUDY DESIGN  , Non Controlled Experimental Study.

APPROPRIATE METHODS OF MEASUREMENT

 1. Standardized Homoeopathic case taking proforma will be used in each case.

2. Improvement of patient will be determined from the help of Dermatophytosis Area Severity Index.

Final severity score is equals to Sum of Body Surface Area affected in hand units multiplied by summation of  Pruritus score, Erythema score, Lichenification score ,  Active Raised Boarders score  , with addition of 1 for each Additional Risk factor.

Duration of study is 18 months. Duration of each case is , Each case will be studied for a period of 6 months or if remission occur, whichever is earlier. Duration of Follow up, Each case will be followed up at the interval of 15 days or as and when required. Clinical assessment will be done at baseline, 3rd month and at the end of the treatment or 6th month, whichever is earlier. Score before and after treatment will be compared to assess the improvement. Based on difference between pre and post treatment score of scale, and disease will be assessed as Mild, Moderate, Severe. And patient will be assessed as Improved, Partial improved, Not improved.

This is a non controlled, prospective clinical study intended to explore the role of individualized homoeopathic medicine in fifty millesimal potency  treatment in the management of Tinea corporis.

 

 

 

 

 

 

 
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