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CTRI Number  CTRI/2025/10/095886 [Registered on: 10/10/2025] Trial Registered Prospectively
Last Modified On: 09/10/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Surgical/Anesthesia 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   “Evaluating Block Onset, Ease of Performance and Safety in different costoclavicular Brachial Plexus Block Techniques: Medial and Lateral by using ultrasound in patients undergoing upper limb surgery 
Scientific Title of Study   Comparative evaluation of performance and block charachterstics of medial versus lateral approach to ultrasound guided Costoclavicular Brachial Plexus block in patients undergoing upper limb surgery 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Bahadur Singh 
Designation  Post Graduate Student 
Affiliation  ESIC Medical College and Hospital Faridabad Haryana 
Address  Department Of Anaesthesia ESIC Medical College and Hospital Faridabad

Faridabad
HARYANA
121001
India 
Phone  8930680081  
Fax    
Email  sdrbahadur@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Rama Wason 
Designation  Professor 
Affiliation  ESIC Medical College and Hospital Faridabad Haryana 
Address  Department Of Anaesthesia ESIC Medical College and Hospital Faridabad

Faridabad
HARYANA
121001
India 
Phone  8930680081  
Fax    
Email  nupur4@hotmail.com  
 
Details of Contact Person
Public Query
 
Name  Rama Wason 
Designation  Professor 
Affiliation  ESIC Medical College and Hospital Faridabad Haryana 
Address  Department Of Anaesthesia ESIC Medical College and Hospital Faridabad

Faridabad
HARYANA
121001
India 
Phone  8930680081  
Fax    
Email  nupur4@hotmail.com  
 
Source of Monetary or Material Support  
ESIC Medical College and Hospital Faridabad 121001 Haryana India 
 
Primary Sponsor  
Name  Dr Bahadur Singh 
Address  Department Of Anaesthesiology ESIC Medical College and Hospital Faridabad 
Type of Sponsor  Other [Self] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Bahadur Singh  ESIC Medical College and Hospital  Department Of Anaesthesia ESIC Medical College And Hospital Faridabad
Faridabad
HARYANA 
8930680081

sdrbahadur@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethics Committee ESIC Medical College and Hospital  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: O||Medical and Surgical,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Comparator Agent  Approach of Costoclavicular Brachial Blexus Block  Two group will be formed group M needle will advance from medial to lateral Group L needle will advance from lateral to medial Comparison Of USG Guided Medial Vs Lateral Approach Of The Block using single injection of 20 cc bupivacaine 0.5%.After LA injection composite sensorimotor score was calculated for Musculocutaneous Median Radial and Ulner nerve every 5 minutes to 30 minutes. 
Intervention  Costoclavicular Brachial Plexus Block  Two group will be formed group M needle will advance from medial to lateral Group L needle will advance from lateral to medial Comparison Of USG Guided Medial Vs Lateral Approach Of The Block using single injection of 20 cc bupivacaine 0.5%.After LA injection composite sensorimotor score was calculated for Musculocutaneous Median Radial and Ulner nerve every 5 minutes to 30 minutes. 
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  65.00 Year(s)
Gender  Both 
Details  American Society of Anaesthesiologists physical status I or II
BMI less than 30 
 
ExclusionCriteria 
Details  Infection at block site
history of allergy to local anaesthetiC
patients with history of coagulopathy or bleeding disorders
 
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   Sequentially numbered, sealed, opaque envelopes 
Blinding/Masking   Participant, Investigator and Outcome Assessor Blinded 
Primary Outcome  
Outcome  TimePoints 
To evaluate and compare the performance time of ultrasound-guided costoclavicular brachial plexus block using medial versus lateral approach in patients undergoing upper limb surgeries.   30 minutes 
 
Secondary Outcome  
Outcome  TimePoints 
To evaluate and compare
The needle passes
The time taken to achieve the composite sensorimotor score of 14
The diaphragmatic excursion (in cm) .
The incidence of complications (e.g., vascular punctures, pneumothorax, )

of medial versus lateral approach of ultrasound guided costoclavicular brachial plexus block in patients undergoing upper limb surgeries
 
30 minutes 
 
Target Sample Size   Total Sample Size="57"
Sample Size from India="57" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   20/10/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)   Not Yet Recruiting 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  
This thesis protocol focuses on comparing the medial versus lateral approaches to ultrasound-guided costoclavicular brachial plexus block in patients undergoing upper limb surgery.

Key Points

Background Brachial plexus blocks are commonly used for upper limb surgeries. The costoclavicular approach offers consistent visualization and reduced complications compared to traditional techniques. However, the medial and lateral approaches to CCB differ in performance ease risk of vascular puncture and block characteristics.
Research Gap Limited studies have directly compared medial and lateral CCB techniques especially regarding onset time performance difficulty and complications.
Aim & Objectives
Primary Compare performance time between medial and lateral approaches.
Secondary Assess needle passes onset of sensorimotor block diaphragmatic excursion block success and complications as vascular puncture pneumothorax.
Methods
Design Randomized controlled trial from October 2025 to March 2027.
Sample Size 54 patients as27 in each group.
Participants Adults aged 18–65 years ASA I/II BMI less than 30 kg/m².
Exclusion Infection at block site allergy to local anaesthetic bleeding disorders.
Groups
Group L Lateral to medial CCB with 20 ml of 0.5% bupivacaine.
Group M Medial to lateral CCB with the same drug.
Outcome Measures Imaging time needling time performance time sensorimotor block scores diaphragmatic excursion complications and patient satisfaction.
Statistical Plan Data analyzed using SPSS v23, with t-tests/ANOVA for continuous data, Chi-square or Fisher’s test for categorical data and p less than 0.05 as significant.
Ethics Institutional Ethical Committee approval obtained. Informed consent will be taken from all participants.

Conclusion of The study aims to clarify whether medial or lateral ultrasound-guided costoclavicular approaches provide better performance and clinical outcomes and helping anaesthesiologists choose the safer and more efficient method for upper limb surgeries.
 
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