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CTRI Number  CTRI/2025/10/095556 [Registered on: 01/10/2025] Trial Registered Prospectively
Last Modified On: 29/09/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Homeopathy 
Study Design  Randomized, Parallel Group, Placebo Controlled Trial 
Public Title of Study   Role Of Homoeopathic Medicine In Atopic Dermatitis 
Scientific Title of Study   To Evaluate The Role Of Individualized Homoeopathic Medicine In The Treatment Of Atopic Dermatitis A Randomized Control Trial 
Trial Acronym  no 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Ravneet kaur 
Designation  PG scholar 
Affiliation  Sri Ganganagar Homoeopathic Medical College Hospital And Research Institute Sri Ganganagar 
Address  Sri Ganganagar Homoeopathic Medical College Hospital And Research Institute Tantia University Near Ricco Bus Stand Hanumangarh Road Sri Ganganagar Ganganagar Rajasthan 335002

Ganganagar
RAJASTHAN
335002
India 
Phone  8837818207  
Fax    
Email  ravneet2620@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr.Deepak Sharma 
Designation  HOD Department Of Paediatrics 
Affiliation  Sri Ganganagar Homoeopathic Medical College Hospital And Research Institute Sri Ganganagar 
Address  Sri Ganganagar Homoeopathic Medical College Hospital And Research Institute Tantia University Near Ricco Bus Stand Hanumangarh Road Sri Ganganagar Ganganagar Rajasthan 335002

Ganganagar
RAJASTHAN
335002
India 
Phone  8837818207  
Fax    
Email  responds@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Ravneet kaur 
Designation  PG scholar 
Affiliation  Sri Ganganagar Homoeopathic Medical College Hospital And Research Institute Sri Ganganagar 
Address  Sri Ganganagar Homoeopathic Medical College Hospital And Research Institute Tantia University Near Ricco Bus Stand Hanumangarh Road Sri Ganganagar Ganganagar Rajasthan 335002


RAJASTHAN
335002
India 
Phone  8837818207  
Fax    
Email  ravneet2620@gmail.com  
 
Source of Monetary or Material Support  
Sri Ganganagar Homoeopathic Medical College Hospital And Research Institute Tantia University Near Ricco Bus Stand Hanumangarh Road Sri Ganganagar Ganganagar Rajasthan 335002 
 
Primary Sponsor  
Name  Sri Ganganagar Homoeopathic Medical College Hospital And Research Institute  
Address  Sri Ganganagar Homoeopathic Medical College Hospital And Research Institute Tantia University Near Ricco Bus Stand Hanumangarh Road Sri Ganganagar Ganganagar Rajasthan 335002 
Type of Sponsor  Research institution and hospital 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Ravneet Kaur  Sri Ganganagar Homoeopathic Medical College Hospital And Research Institute   Room No. 102 Paediatrics Department Sri Ganganagar Homoeopathic Medical College Hospital And Research Institute Tantia University Near Ricco Bus Stand Hanumangarh Road Sri Ganganagar Ganganagar Rajasthan 335002
Ganganagar
RAJASTHAN 
8837818207

ravneet2620@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethics Committee Sri Ganganagar Homoeopathic Medical College Hospital And Research Institute  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: L209||Atopic dermatitis, unspecified,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Individualized Homoeopathic medicine  the dose and repetition of medicine max vary according to the susceptibility and sensitivity of patient. I this trial dosage and repetition will be as per the case and guidelines of organon of medicine under the duration of 3 month 
Comparator Agent  Placebo  The Patient will recieve placebo in homoeopathic globules  
 
Inclusion Criteria  
Age From  1.00 Day(s)
Age To  12.00 Year(s)
Gender  Both 
Details  1.Children of both sexes
2.Age 0-12 year
3.Patient’s parents willing to participate 
 
ExclusionCriteria 
Details  1.Inability to follow the study protocol
2.Children with other skin disease that may complicate the atopic dermatitis
3.Children with chronic disease that may impact study outcome
4.Children or parent may adherent to study protocol 
 
Method of Generating Random Sequence   Coin toss, Lottery, toss of dice, shuffling cards etc 
Method of Concealment   Sequentially numbered, sealed, opaque envelopes 
Blinding/Masking   Participant Blinded 
Primary Outcome  
Outcome  TimePoints 
Reduction in symptoms of atopic dermatitis such
as itching, redness, swelling, oozing in patient by receiving individualized
homoeopathic medicine 
before final exam of part 2 
 
Secondary Outcome  
Outcome  TimePoints 
NIL  NIL 
 
Target Sample Size   Total Sample Size="96"
Sample Size from India="96" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   04/11/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)   Not Yet Recruiting 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary   AIM: To evaluate the efficacy of individualized homoeopathic medicine in the treatment of atopic dermatitis.

 OBJECTIVE: 
1.To identify and evaluate common triggering factors responsible for atopic dermatitis in children. 
2. To study the miasmatic predominance of atopic dermatitis and its homoeopathic approach. 
3. To monitor changes in Scoring of atopic dermatitis (SCORAD) after giving homoeopathic medicine

 INTRODUCTION:
Atopic dermatitis is an inflammatory non-communicable skin disorder. The casual symptoms include itching, typical morphology, and occurrence of rash, chronic relapsing pattern. Itching is the most commonly associated feature. It is usually preceded by rash that might be severe, generally during night that is followed by inflammatory red to brownish colored patches with small bumps. These patches may exudate fluid and crust is formed over them when scratched. They may occur wherever on the body, but they most commonly appear on the flexural surfaces of the joints like inner sides of elbows, knees, and ankles. The skin is dry, scaly with cracks on visual examination making it prone to environmental allergens. There are few factors that worsen the presentation of dermatitis. Environmental factors like staphylococcal skin infection, humidity, pollution, exposure to detergents and stress plays crucial role as a precipitating factor. The etiology for dermatitis is destruction of epidermal barrier destruction by immune system 12 disharmony as a result of gene environmental interaction. Stress is also a very crucial factor in depression. 

STUDY PROCEDURE: This clinical study aims to evaluate the effectiveness of individualized homeopathic treatment for atopic dermatitis, beginning with a target sample size of 96 participants. Each patient undergoes a thorough case-taking process, including detailed history, general physical examination, and specific assessment for atopic dermatitis, with diagnosis confirmed using ICD-10 criteria. Eligible patients are then randomized into two equal groups of 48 using a shuffled deck of cards—assigning even numbers to the treatment group and odd numbers to the control group. Baseline severity of atopic dermatitis is assessed using the SCORAD scale before initiating individualized homeopathic treatment for the treatment group. Participants are followed up at intervals of 15 days, 1 month, 2 months, and 3 months, with flexibility based on clinical condition. At the end of all follow-ups, SCORAD scoring is repeated to evaluate clinical improvement in both groups. The collected data is analyzed using appropriate statistical tools to interpret changes in scores, comparing the treatment group with the placebo group. Finally, the study concludes with the formulation of results and discussion based on the observed outcomes.
  
 
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