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CTRI Number  CTRI/2025/10/095877 [Registered on: 10/10/2025] Trial Registered Prospectively
Last Modified On: 10/10/2025
Post Graduate Thesis  Yes 
Type of Trial  Observational 
Type of Study   Cohort Study 
Study Design  Other 
Public Title of Study   Observing how special recovery guidelines (ERAS) affect patient outcomes after testicular cancer surgery. 
Scientific Title of Study   A prospective observational study to assess the compliance to enhanced recovery protocols and postoperative outcomes in patients undergoing retroperitoneal lymph node dissection surgeries for testicular germ cell tumor patients. 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Anjana Wajekar 
Designation  Professor 
Affiliation  Tata Memorial Centre 
Address  ACTREC, Tata Memorial Centre, Homi Bhabha National Institute. Sector 22, Utsav Chowk - CISF Rd, Owe Camp, Kharghar, Navi Mumbai, Maharashtra

Mumbai (Suburban)
MAHARASHTRA
410210
India 
Phone  9930104106  
Fax    
Email  anjanawajekar@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Anjana Wajekar 
Designation  Professor 
Affiliation  Tata Memorial Centre 
Address  ACTREC, Tata Memorial Centre, Homi Bhabha National Institute. Sector 22, Utsav Chowk - CISF Rd, Owe Camp, Kharghar, Navi Mumbai, Maharashtra


MAHARASHTRA
410210
India 
Phone  9930104106  
Fax    
Email  anjanawajekar@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Anjana Wajekar 
Designation  Professor 
Affiliation  Tata Memorial Centre 
Address  ACTREC, Tata Memorial Centre, Homi Bhabha National Institute. Sector 22, Utsav Chowk - CISF Rd, Owe Camp, Kharghar, Navi Mumbai, Maharashtra


MAHARASHTRA
410210
India 
Phone  9930104106  
Fax    
Email  anjanawajekar@gmail.com  
 
Source of Monetary or Material Support  
NIL 
 
Primary Sponsor  
Name  Tata Memorial Centre 
Address  Homi Babha Building, Dr Ernest Borges Rd, Parel East, Parel, Mumba 
Type of Sponsor  Government medical college 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Suraj Yadav  Tata Memorial Centre  Ernest Borges Road, Tata Memorial hospital, Parel, Mumbai
Mumbai
MAHARASHTRA 
8668762685

doctorsurajyadav@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
TMC-IEC III  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: C629||Malignant neoplasm of testis, unspecified whether descended or undescended,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Nil  Nil 
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  99.00 Year(s)
Gender  Male 
Details  All Adult Males more than 18 years of age undergoing RPLND Surgery 
 
ExclusionCriteria 
Details  1.Patients with severe comorbidities or contraindications that significantly impact surgical or postoperative management, such as advanced heart failure, severe chronic obstructive pulmonary disease, or end-stage renal disease
2.Patients in whom surgery was abandoned due to inoperability 
 
Method of Generating Random Sequence   Not Applicable 
Method of Concealment   Not Applicable 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
To assess the percentage compliance of the enhanced recovery pathway and it’s influence on the postoperative complications (defined by Clavien Dindo Classification) in patients undergoing RPLND surgery.  30 days post surgery  
 
Secondary Outcome  
Outcome  TimePoints 
1.Postoperative length of hospital stay (LOS)
2.30-day readmission rate  
30 days post operatively 
 
Target Sample Size   Total Sample Size="150"
Sample Size from India="150" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   21/10/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="2"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  
1. What the study is about?
This is an observational study looking at how patients recover after a major operation called Retroperitoneal
Lymph Node Dissection (RPLND). This surgery is often needed for testicular cancer. We will see how well
special care plans, known as "enhanced recovery protocols," are being used and how they affect patients’
recovery. These special plans include things done before, during, and after surgery to help patients get better
faster and with fewer problems.
2. Who will be included in this study?
Adult patients (18 years or older) who are scheduled to have this specific RPLND surgery for testicular
cancer may be part of this study.
Patients who have very serious other health problems that could greatly affect their surgery or recovery, or if
their planned surgery cannot be completed, would not be included.
The study will begin after the Institutional ethics committee (IEC) approval and Clinical Trials Registry of
India registration. The study will be conducted at both ACTREC, Tata Memorial Centre, Navi Mumbai and
TMH, Tata Memorial Centre, Parel.
3. What information is collected and how patients are monitored?
There are certain "enhanced recovery" steps which are proven to benefit patients undergoing major
surgeries. Education regarding these steps will be provided to all anaesthesia and surgical trainees, nurses,
nutritionists and physiotherapists as part of a multidisciplinary team. The study will collect information
about how closely the "enhanced recovery" steps are followed for each patient. This includes things like:
Before surgery: Advice given, efforts to stop smoking/alcohol, nutrition checks, and exercises.
During surgery: Type of anaesthesia, fluids given, how body temperature was kept normal, etc.
After surgery: Pain relief, how quickly patients get moving and eating, and when tubes are removed.
We will also gather general information like age, overall health, details about the surgery (like how long it
took), any postoperative complications, how long patients stay in the hospital, and if they need to be
readmitted to the hospital within 30 days. This information will be collected by a research nurse from the
patients’ medical records/ anesthesia notes/ surgery notes. There will be no direct contact with the patients.
4. Data safety and confidentiality
Case record forms (physical copies) will be stored in the office of the principal investigator, which will be
accessible only to the principal and co-investigators. Each study participant will be assigned an ID code.
Patient confidentiality will be maintained during data analysis.
5. Ethical Consideration
This is an observational study, which does not alter the method of treatment or care offered to the patients by
any means.
 
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