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Primary
Objectives To Study the
Utility of Rubrics from Boger Boenninghausens Characteristics and Repertory
in the management of Acute Febrile Illness in the age group of 18 to 40
years.
Other
Objectives 1 To study
clinical presentation of Acute Febrile Illness.
Other
Objectives 2 To compare
pre and post oral temperature values in acute febrile illness.
Other
Objectives 3 To study
the actual time period required to improve the individual of acute febrile
illness.
MATERIALS AND METHODOLOGY
1. Type of
study design An Experimental Non-Controlled Study.
2. Setting Cases will be collected from the OPD of the
Institute.
3. Duration of
study 18 months
4. Method of
selection of study subjects:
INCLUSION CRITERIA
1. Patient with 18to 40 years of age will be
considered.
2. Oral temperature (by using mercury
thermometer) of individual having 99F to 104F i.e Low to moderate grade fever
for more than 2 or 3 days will be taken for study.
3. Patient of
both gender will be considered.
4. Patients with fever secondary to common
localized diseases like Urinary tract infection, abscess , boil, eye
infection, ear infection etc will also be considered.
5. Patient who
are taking any other ineffective medications for fever.
EXCLUSION CRITERIA
1. Patient who are having temperature more
than 104F.
2. Patient who are having fever with severe
systemic diseases (pneumonia, liver cirrhosis,renal calculi etc.) will be
excluded.
3. Patient with suspected immunocompromised
disease and suspected malignancies or pre-malignancy will be excluded.
4. Patient who are Pregnant and lactating
female will be excluded.
SUBJECT WITHDRAWAL
CRITERIA
1. Patients who does not wish to continue the treatment.
2. Patients who do not follow up regularly.
3. Case requiring emergency management in acute febrile illness.
5. Method of selection of comparison or control group Not applicable
6. Matching Criteria Not applicable
8.
Specification of instruments and related measurements
1. Complete
Homoeopathic Case Taking Proforma will be used in each case.
2. Temperature
values will be recorded for acute febrile illness in each case, only pre and
post temperature values will be studied for statistical calculation of study.
3. Intensity of
Clinical features pre and post treatment will be considered for acute febrile
illness in each case.
4. Actual time
period required to improve the temperature in the individuals will be
considered for acute febrile illness.
5. Temperature
value will be recorded on every 2nd day by telephonic
means, maintaining fever chart and follow up.
6. Will be doing
CBC as per requirement of case.
7. Those patients
who are having pain will be assessed by the VAS scale to asses improvement.
8. Temperature
chart for OPD patients
Outcome will be
assessed in terms of:
1. Improved
2. Not improved
1. Sample size 45 patients will be selected.
2. Sampling
technique Non probability Purposive sampling based on
inclusion and exclusion criteria.
3. Method for
data collection relevant to objective
1. Purposive
Sampling based on inclusion and exclusion criteria will be done.
2. Detailed
homoeopathic case taking will be done as per the proforma and case processing
will be done in detail so as to aid selection of similimum by using Boger
Boenninghausen Characteristics and Repertory.
3. Cases will be
recorded from the Institute’s OPD.
4. Each case will
be studied for around 2 weeks
5. Depending upon
the clinical presentation of the patient and totality erected, the patient
will be administered appropriate Similimum.
4. Study
Instrument or Data Collection Tools
1. Complete
Homoeopathic case taking format to form a totality.
2. Appropriate
reference books like Homoeopathic Materia Medica, Medicine books, Repertory
Textbooks, different Homoeopathic journals and research papers will be
considered.
3. HOMPATH CLASSIC
Software will be used for repertorisation through The Boger Boenninghausen
Characteristic and Repertory.
5. Data
management and analysis Procedure
1. Framing of
totality of symptoms- will be done as per the principles of Homoeopathy.
2. Selection of
remedy - Individualized Homoeopathic Medicines based on totality of symptoms.
3. The Posology -
Appropriate potency will be selected based on the susceptibility of each
case. Potency will be changed when required.
4. Duration of
study - 18 months
5. Duration of
each case Each case will be studied
for up to 14 days or till recovery, whichever will be earlier
6. Duration of
follow up Each case will be followed
up at the interval of 24 hours or earlier if required till improvement of
case..
6. Plan for
Statistical analysis
1. Data collected
will be compiled on to a MS Office excel worksheet and will be subjected to
statistical analysis using an appropriate package like SPSS software.
Descriptive statistics like frequency andpercentage of categorical data, mean and Standard
deviation of numerical data in each time interval will be depicted.
2. Normality of
numerical data will be checked using Shapiro Wilk test or Kolmogorov Smirnov test.
Depending on the normality of data, statistical tests will be determined.
3. Intra group
comparisons for a numerical continuous data following a normal distribution
will be done using paired t test (for 2 observations) else a non parametric
substitute like Wilcoxon signed rank test (for 2 observations) will be used.
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