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CTRI Number  CTRI/2025/09/095430 [Registered on: 26/09/2025] Trial Registered Prospectively
Last Modified On: 24/04/2026
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Physiotherapy (Not Including YOGA) 
Study Design  Randomized, Parallel Group, Active Controlled Trial 
Public Title of Study   Does square-stepping exercise improve balance and walking speed in people recovering from stroke? 
Scientific Title of Study   To study the effectiveness of Square Stepping Exercise on Balance and Gait velocity in post-stroke patients 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Yuvasri H 
Designation  Post Graduate Student - Advanced Neurology 
Affiliation  Government Medical College and Hospital - Cuddalore 
Address  Room no. 313, Department of Physiotherapy, Division of PMR, Government Medical College and Hospital, Annamalai Nagar, Cuddalore
Room no. 313, Department of Physiotherapy, Division of PMR, Government Medical College and Hospital, Annamalai Nagar, Cuddalore
Cuddalore
TAMIL NADU
608002
India 
Phone  9384649795  
Fax    
Email  yuvasrihemanathan@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  R Sampath Pulimoot 
Designation  Assistant Professor 
Affiliation  Government Medical College and Hospital - Cuddalore 
Address  Department of PMR, Government Medical College and Hospital, Annamalai Nagar, Cuddalore

Cuddalore
TAMIL NADU
608002
India 
Phone  9443449829  
Fax    
Email  sampulimoot@gmail.com  
 
Details of Contact Person
Public Query
 
Name  R Sampath Pulimoot 
Designation  Assistant Professor 
Affiliation  Government Medical College and Hospital - Cuddalore 
Address  Department of PMR, Government Medical College and Hospital, Annamalai Nagar, Cuddalore

Cuddalore
TAMIL NADU
608002
India 
Phone  9443449829  
Fax    
Email  sampulimoot@gmail.com  
 
Source of Monetary or Material Support  
Room no. 313, Department of Physiotherapy, Division of PMR, Government Medical College and Hospital, Annamalai Nagar, Cuddalore - 608002 
 
Primary Sponsor  
Name  Yuvasri H 
Address  Department of PMR, Government Medical College and Hospital-Cuddalore, Annamalai Nagar, Cuddalore -608002 
Type of Sponsor  Other [Self] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr S Arul Pragassame  Government Medical College and Hospital - Cuddalore  Room no.313, Department of PMR, Government Medical College and Hospital—Cuddalore, Annamalai nagar,Cuddalore
Cuddalore
TAMIL NADU 
98423 85544

arulphysio77@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Human Ethics Committee  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: G819||Hemiplegia, unspecified,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Comparator Agent  Conventional physiotherapy   Conventional physiotherapy program for balance and gait training, delivered 3 times per week for 6 weeks. This includes traditional balance exercises, gait training, and strengthening as per routine rehabilitation protocols. 
Intervention  Square Stepping Exercise along with Conventional physiotherapy   quare Stepping Exercise (SSE) program: supervised progressive SSE protocol delivered 3 times per week for 6 weeks. Each session lasts 30 minutes and includes warm-up, structured stepping patterns on a 25-cell mat, progression of complexity, and cool-down. Delivered by a trained physiotherapist. 
 
Inclusion Criteria  
Age From  45.00 Year(s)
Age To  60.00 Year(s)
Gender  Both 
Details  1.Stroke patients with unilateral or hemispherical diagnosed with CVA based on MRI and CT.
2.Patients aged between 45 and 60 years.
3.Patients with post-stroke duration from 3 to 9 months post stroke.
4.Patients with Fall Efficacy Scale score of 16.
5.Patients who can ambulate 10 metres independently.
6.Medically stable and cleared for physical activity by a physician.
7.Patients demonstrating Brunnstrom stage of recovery 3,4,5 indicating moderate motor recovery with potential for functional improvement.
8.Ability to comprehend and follow oral instruction
 
 
ExclusionCriteria 
Details  1.Patients with other neurological conditions affecting motor function
2.Perceptual Dysfunction
3.More than one Episode of stroke
4.Patients with significant musculoskeletal disorders or lower limb injuries affecting mobility
5.Patients with uncorrected Auditory and visual Deficits
6.Patients with Aphasia 
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   Sequentially numbered, sealed, opaque envelopes 
Blinding/Masking   Outcome Assessor Blinded 
Primary Outcome  
Outcome  TimePoints 
Berg Balance Scale

10-Meter Walk Test

 
9 months

 
 
Secondary Outcome  
Outcome  TimePoints 
NIL  NIL 
 
Target Sample Size   Total Sample Size="20"
Sample Size from India="20" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   11/10/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="0"
Months="10"
Days="0" 
Recruitment Status of Trial (Global)   Not Yet Recruiting 
Recruitment Status of Trial (India)  Open to Recruitment 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary
Modification(s)  

Stroke is a leading cause of long-term disability globally, frequently resulting in impaired balance and gait velocity, which in turn compromise functional mobility and increase fall risk (Langhorne et al., 2011). These motor deficits greatly impact the individual’s ability to perform daily activities independently, affecting their quality of life and social participation (Jørgensen et al., 1995). Among post-stroke individuals, impaired balance is one of the most significant predictors of falls and reduced community ambulation (Mao et al., 2002).

Conventional physiotherapy has been shown to improve balance and gait after stroke; however, the high cost, need for specialized supervision, and long-term commitment often limit its accessibility, especially in low-resource or rural settings (Pollock et al., 2014). This underscores the importance of exploring scalable, task-specific, and cost-effective rehabilitation strategies that enhance recovery of balance and gait while promoting functional independence.

Square Stepping Exercise (SSE) is a structured, low-cost, and adaptable exercise program that involves performing specific foot patterns on a gridded mat. Originally developed by Shigematsu and Okura to improve balance and prevent falls in older adults, SSE has shown promise in enhancing coordination, lower limb strength, and cognitive-motor integration. However, despite its proven utility in geriatric populations, SSE is not well established in stroke rehabilitation. The cognitive demand of memorizing and executing step sequences adds a dual-task component that may be particularly beneficial for stroke patients, who often exhibit deficits in both motor and cognitive domains. Therefore, exploring the efficacy of SSE in stroke recovery may provide a novel, evidence-based approach to enhancing post-stroke rehabilitation outcomes. 

 
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