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CTRI Number  CTRI/2026/01/100806 [Registered on: 12/01/2026] Trial Registered Prospectively
Last Modified On: 12/01/2026
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Other (Specify) [FM theta EEG Neurofeedback ]  
Study Design  Other 
Public Title of Study   Effect of brainwave assisted Focused attention training on mind wandering in healthy people 
Scientific Title of Study   Mapping of EEG-microstate-dynamics and the effect of frontal-midline-theta training on phenomenology of spontaneous mentation among healthy adults 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  RAVINDRA PN 
Designation  Additonal Professor  
Affiliation  National Institute of Mental Health and Neurosciences (NIMHANS) 
Address  Center for Consciousness studies, Department of Neurophysiology, Hosur Road, National Institute of Mental Health and Neurosciences (NIMHANS).

Bangalore
KARNATAKA
560029
India 
Phone  09448934488  
Fax    
Email  ravindrapinna@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Amritharekha P 
Designation  Ph.D. student  
Affiliation  National Institute of Mental Health and Neurosciences (NIMHANS) 
Address  Center for Consciousness studies, Department of Neurophysiology, Hosur Road, National Institute of Mental Health and Neurosciences (NIMHANS).

Bangalore
KARNATAKA
560029
India 
Phone  9740247474  
Fax    
Email  amritharekhanayak@gmail.com  
 
Details of Contact Person
Public Query
 
Name  RAVINDRA PN 
Designation  Additonal Professor  
Affiliation  National Institute of Mental Health and Neurosciences (NIMHANS) 
Address  Center for Consciousness studies, Department of Neurophysiology, Hosur Road, National Institute of Mental Health and Neurosciences (NIMHANS).

Bangalore
KARNATAKA
560029
India 
Phone  09448934488  
Fax    
Email  ravindrapinna@gmail.com  
 
Source of Monetary or Material Support  
National Institute of Mental Health and Neurosciences (NIMHANS) 
 
Primary Sponsor  
Name  Dr Ravindra PN  
Address  Additional Professor, Centre for Consciousness Studies Department of Neurophysiology NIMHANS.  
Type of Sponsor  Other [Self] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
DR RAVINDRA PN  National Institute of Mental Health and Neurosciences  Center for Consciousenss Studies, Human Cognition Laboratory Department of Neurophysiology, NIMHANS, Hosur Rd, near Bangalore Milk Dairy, Hombegowda Nagar, Bengaluru, Karnataka 560029
Bangalore
KARNATAKA 
09448934488

RAVINDRAPINNA@GMAIL.COM 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
NIMHANS Institute Ethics committee Basic and Neuroscience division  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Healthy Human Volunteers  Healthy 
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  EEG Frontal-midline theta Neuro-feedback   EEG based Neuro-feedback specifically to enhance Frontal-midline theta (FM-theta) activity will be the intervention. Modalities to enhance FM theta will be different breathing protocols; breathing induced EEG (FM-theta) changes will be feedback given in the gamified way. The study design is cross-over design where each subjects undergo Neuro-feedback training protocol for 8 days spanning 2 weeks and it is compared against their sham training session.  
Comparator Agent  Sham EEG based Frontal-midline theta (FM-theta) Neuro-feedback   In sham training session the same breathing protocols will be followed except the feedback received will not match their EEG (FM-theta) changes. The neuro-feedback and sham session will be at a minimum of 4 weeks apart.  
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  35.00 Year(s)
Gender  Both 
Details  Healthy volunteers
Age 18-35 years
Both genders
PHQ 9 scored between 0-9 
 
ExclusionCriteria 
Details  Subjects with neurological neurodegenerative neuropsychiatric conditions and on medications
PGQ 9 scored more than 10
 
 
Method of Generating Random Sequence   Not Applicable 
Method of Concealment   Not Applicable 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
EEG microstates and Mind wandering  2 weeks 
 
Secondary Outcome  
Outcome  TimePoints 
NIL  NIL 
 
Target Sample Size   Total Sample Size="12"
Sample Size from India="12" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   31/01/2026 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="2"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  
The EEG based neurofeedback is a noninvasive non pharmacological approach to modulate cognitive functions underlying attention and emotional regulation.  A Study reported giving Frontal midline EEG activity in theta range as feedback using breathing protocols enhances executive functioning of the participants . They employed eight days of protocol in where training is done within two consecutive weeks. Inspired by this we are employing the same protocol for understanding mind wandering phenomenology. Internal focus such as Meditation increases FM theta oscillations . And Mind wandering is a common confounder seen during sustained attention periods. Thus training individuals in focused attention methods might impact mind-wandering episodes. In present study the participants will undergo 2week FM theta training focused on understanding the effect of focused attention training on the phenomenology of mind wandering (spontaneous mentation). Assessment of pre and post Mind wandering will be done via sustained attention paradigm, where participants are probed with questions related to their attention status and also will encourage them to report when every they self-catch their thoughts during the sustain attention task. The whole protocol will be of 2 weeks span and with minimum of 4 weeks time for wash out subject will undergo sham training protocols. The study design is cross over where half of the participants will receive FM theta training protocol and other half sham protocol as their first session subsequently after the washout gap they will receive the other half. 
Study hypothesis
Frontal-midline theta focused attention training will influence the contents of spontaneous mentation (mind wandering) and its EEG microstate dynamics
Aim
To evaluate the effect of frontal-midline-theta focused attention training on phenomenology of spontaneous mentation and its EEG microstate dynamics among healthy adults

 
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