FULL DETAILS (Read-only)  -> Click Here to Create PDF for Current Dataset of Trial
CTRI Number  CTRI/2026/01/101401 [Registered on: 16/01/2026] Trial Registered Prospectively
Last Modified On: 12/01/2026
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Homeopathy 
Study Design  Single Arm Study 
Public Title of Study   Study to identify common mental symptoms in skin disease patients using Synthesis 9.0 homoeopathic repertory. 
Scientific Title of Study   An Analytical Study of Rubrics of Mind in Psychodermatology using Synthesis 9.0 Repertory. 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Rajeshwari Chandrashekhar Gaidhane 
Designation  PG Scholar 
Affiliation  Motiwala (National) Homoeopathic Medical College and hospital  
Address  Department of Homoeopathic repertory and case taking, Motiwala (National) homoeopathic medical college, Dhruv Nagar Satpur colony, Nashik

Nashik
MAHARASHTRA
422012
India 
Phone  9588413370  
Fax    
Email  rad.gaidhane@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Kirti Dinesh Kadam 
Designation  Associate Professor 
Affiliation  Motiwala National Homoeopathic Medical College and Hospital  
Address  Department of Homoeopathic Repertory and case taking, Motiwala (National) homoeopathic medical college, Dhruv Nagar Satpur colony, Nashik

Nashik
MAHARASHTRA
422012
India 
Phone  9527224001  
Fax    
Email  kadamkirti2709.kk@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Dr Rajeshwari Chandrashekhar Gaidhane 
Designation  PG Scholar 
Affiliation  Motiwala National Homoeopathic Medical College and hospital  
Address  Department of Homoeopathic Repertory and case taking, Motiwala (National) homoeopathic medical college, Dhruv Nagar Satpur colony, Nashik

Nashik
MAHARASHTRA
422012
India 
Phone  9588413370  
Fax    
Email  rad.gaidhane@gmail.com  
 
Source of Monetary or Material Support  
Motiwala (National) Homoeopathic Medical College and Hospital Dhruv Nagar Satpur colony Nashik 422012 
 
Primary Sponsor  
Name  Dr Rajeshwari Chandrashekhar Gaidhane 
Address  Department of Homoeopathic Repertory and case taking dhruv nagar Satpur colony Nashik 422012 
Type of Sponsor  Other [Self] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Rajeshwari Chandrashekhar Gaidhane  Motiwala National Homoeopathic Medical College Nashik  Department of Homoeopathic Repertory and case taking Dhruv Nagar Satpur colony Nashik 422012
Nashik
MAHARASHTRA 
9588413370

rad.gaidhane@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethical Cell Motiwala Homoeopathic Medical College  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: L509||Urticaria, unspecified, (2) ICD-10 Condition: L700||Acne vulgaris, (3) ICD-10 Condition: B359||Dermatophytosis, unspecified, (4) ICD-10 Condition: L409||Psoriasis, unspecified, (5) ICD-10 Condition: L209||Atopic dermatitis, unspecified, (6) ICD-10 Condition: L219||Seborrheic dermatitis, unspecified, (7) ICD-10 Condition: L259||Unspecified contact dermatitis, unspecified cause,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  An Analytical Study of Rubrics of Mind in Psychodermatology Using Synthesis 9.0 Repertory.  After Homeopathic case taking indicated homeopathic medicines will be prescribe with different potencies according to susceptibility of each patient. Followup will be taken after 15 days or as per need for period of 12 months. The progress will be monitored by Dermatology Life Quality Index Questionnaire DLIQ scale before and after the treatment. Homeopathic treatment efficacy will be monitored by MONARCH criteria at the end of the treatment. 
Comparator Agent  NIL  Single Arm Study 
 
Inclusion Criteria  
Age From  16.00 Year(s)
Age To  60.00 Year(s)
Gender  Both 
Details  1.Patient with skin conditions including dermatitis.
psoriasis acne urticaria Tinea infections.
2.Patient with mind history.
3.Age 16 to 60 years.
4.Patient willing to give consent. 
 
ExclusionCriteria 
Details  1.Dermatological conditions except Dermatitis
Psoriasis Tinea infections acne and urticaria.
2.Dermatological conditions without psychological involvement example burns mechanical injuries.
3.Severe Psychiatric Disorders untreated schizophrenia.
4.During Pregnancy and lactating females.
5.Patient not willing to give consent. 
 
Method of Generating Random Sequence   Not Applicable 
Method of Concealment   Not Applicable 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
Improving in patients of psychodermatological cases following homoeopathic prescription based on selected rubrics of mind from Synthesis 9.0 Repertory and using DLQI scale.  On alternative follow up which is to be taken every 15 days or as per need for period within 18 months. 
 
Secondary Outcome  
Outcome  TimePoints 
To analyse the usefulness, pattern and most frequently used mind rubrics in psychodermatological cases using Synthesis 9.0 repertory.   after 18 months 
 
Target Sample Size   Total Sample Size="30"
Sample Size from India="30" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   30/01/2026 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="2"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

Title & Focus

Analytical study of Mind rubrics in Psychodermatology using Synthesis Repertory 9.0.

Emphasizes the mind–skin relationship in homeopathic practice.

Research Gap

Psychodermatology is under-explored in homeopathy as an integrated mind–skin approach.

Existing studies address mental disorders and skin diseases separately, not holistically.

Limited analytical studies on mind rubrics in dermatological conditions.

Research Question & Hypothesis

Research Question: Are mind rubrics from Synthesis 9.0 useful in psychodermatological cases?

Hypothesis (H1): Mind rubrics are useful.

Null Hypothesis (H0): Mind rubrics are not useful.

Introduction to Psychodermatology

Psychodermatology studies bidirectional interaction between mind and skin.

Emotional factors like stress, anxiety, grief, fear, depression influence skin diseases.

About 25–30% dermatology patients have associated psychological disorders.

Homeopathy is suitable due to its holistic and individualized approach.

Skin: Structure & Classification

Skin is the largest organ, derived from ectoderm.

Three layers: epidermis, dermis, hypodermis.

ICD-10 classifications included for:

Dermatitis

Psoriasis

Urticaria

Acne

Tinea (Dermatophytosis)

Major Skin Diseases Discussed

Atopic dermatitis – stress, itching, lichenification

Seborrheic dermatitis – stress-aggravated

Contact dermatitis – irritant or allergic

Neurodermatitis – itch-scratch cycle, stress related

Psoriasis – immune-mediated, stress-triggered

Tinea – fungal infection, stress-induced susceptibility

Acne – hormonal and emotional factors

Urticaria – histamine release, emotional stress triggers

Psychodermatology Concepts

Skin diseases are not merely local, but psychosomatic.

Emotional factors can:

Cause disease

Aggravate disease

Maintain chronicity

Mind influences immunity via Neuro-Immuno-Cutaneous System (NICS).

Wittkower’s Classification

Always psychogenic – Dermatitis artefacta, trichotillomania

Large psychogenic factor – Acne, neurodermatitis

Precipitated by emotions – Psoriasis, urticaria

Psychogenic overlay – Acne vulgaris, eczema, vitiligo

Psycho-Neuro-Endocrino-Immunology (PNEI) Axis

Integrates:

Nervous system

Endocrine system

Immune system

Explains stress-induced flare-ups in skin diseases.

Supports holistic therapeutic models.

Homeopathy & Psychodermatology

Hahnemann emphasized mental symptoms in every disease.

Mental diseases are not separate from physical diseases.

Aphorisms 216–225 describe psychosomatic illness.

Mental states often precede physical manifestations.

 Importance of Repertorization

Repertory is essential to convert symptoms into remedies.

Synthesis Repertory 9.0:

Based on Kent’s philosophy

Rich in mental rubrics

Linked with RADAR software

Ideal for psychodermatological cases due to emphasis on mental generals.

Important Mind Rubrics Highlighted

Mind – ailments from grief, anger, fear, disappointment

Mind – anxiety with eczema

Mind – sadness with acne

Mind – anguish with skin eruptions

Mind – suppressed eruptions with mental symptoms

Objectives

Primary: Analyze usefulness of mind rubrics in psychodermatology.

Secondary:

Identify pattern and frequency of mind rubrics

Correlate mind symptoms with skin diseases

Methodology

Study design: Case series

Sample size: 30 cases

Study duration: 18 months

Tools used:

DLQI scale

CRF

RADAR – Synthesis 9.0

Inclusion & Exclusion Criteria

Included: Skin diseases with psychological involvement, age 16 years and above

Excluded: Mechanical injuries, burns, severe psychiatric illness

Outcome Assessment

Assessment based on change in DLQI score

Improvement reflects better quality of life and symptom control

Ethical Considerations

Informed consent taken

Confidentiality maintained

Conclusion Orientation

Study supports holistic homeopathic management

Mind rubrics play a significant role in treating psychodermatological disorders

Reinforces mind–body unity in disease expression and cure

 

 

 
Close