| CTRI Number |
CTRI/2025/09/094838 [Registered on: 16/09/2025] Trial Registered Prospectively |
| Last Modified On: |
15/09/2025 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Physiotherapy (Not Including YOGA) |
| Study Design |
Randomized, Parallel Group Trial |
|
Public Title of Study
|
Comparison of Nerve Movement exercise and Muscle Release Techniques for Reducing Pain and Improving Neck and Arm Function in Patients with Cervical Nerve Compression |
|
Scientific Title of Study
|
Effect of Neural Mobilisation versus Gross Myofascial Release of Upper Limb and Neck in Patients with Cervical Radiculopathy on Pain, Range of Motion and Function: A Randomized Clinical Trial |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Rani Hubli |
| Designation |
Post Graduate |
| Affiliation |
KAHER Institute of Physiotherapy |
| Address |
Advanced Physiotherapy center, room no.39 department of orthopedic manual therapy room no. 13, sagar floor, Belgaum
Karnataka 590010 India
Belgaum
KARNATAKA
590010
India |
| Phone |
6362377204 |
| Fax |
|
| Email |
ranihubli2411@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Apeksha Hungund |
| Designation |
Assistant Professor |
| Affiliation |
KAHER Institute of Physiotherapy |
| Address |
Advanced Physiotherapy center, room no.39 department of orthopedic manual therapy room no. 13, sagar floor, Belgaum
Karnataka 590010 India
Belgaum
KARNATAKA
590010
India |
| Phone |
8310725829 |
| Fax |
|
| Email |
apeksha_hungund@klekipt.edu.in |
|
Details of Contact Person
Public Query
|
| Name |
Rani Hubli |
| Designation |
Post Graduate |
| Affiliation |
KAHER Institute of Physiotherapy |
| Address |
Advanced Physiotherapy center, room no.39 department of orthopedic manual therapy room no. 13, sagar floor, Belgaum
Karnataka 590010 India
Belgaum
KARNATAKA
590010
India |
| Phone |
6362377204 |
| Fax |
|
| Email |
ranihubli2411@gmail.com |
|
|
Source of Monetary or Material Support
|
| KLE Dr. Prabhakar Kore hospital and research center, Nehru Nagar, Belagavi -590010 Karnataka, India |
|
|
Primary Sponsor
|
| Name |
KAHER Institute of Physiotherapy |
| Address |
KAHER Institute of Physiotherapy, JNMC campus, Nehru Nagar, Belagavi- 590010 Karnataka, India |
| Type of Sponsor |
Research institution and hospital |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Apeksha Hungund |
KAHER Institute of Physiotherapy |
Advanced Physiotherapy center, room no.39 department of orthopedic manual therapy room no. 13, sagar floor, Belgaum
Karnataka, India 590010
Belgaum
KARNATAKA |
6362377204
ranihubli2411@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Research and ethical committee KAHER institute of physiotherapy |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Healthy Human Volunteers |
Cervical Radiculopathy |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Comparator Agent |
Gross Myofascial Release |
The subjects will be given gross myofascial for 6 sessions over 2 weeks (total intervention duration: 2 weeks) in which this technique will be applied to the upper limb and cervical musculature by giving gentle manual traction to the affected limb an stretching of cervical muscles by applying gentle pressure in supine position. Prior to this hot moist pack, neck isometrics and transcutaneous electrical nerve stimulation will be given |
| Intervention |
Neural Mobilisation |
The subjects will be given Neural Mobilisation for 6 sessions over 2 weeks (total intervention duration: 2 weeks), where the affected nerve will be assessed and mobilisation of that nerve will be given in supine position with tensioners/gliders. Prior to which hot moist pack, neck isometrics and transcutaneous electrical stimulation will be given. |
|
|
Inclusion Criteria
|
| Age From |
32.00 Year(s) |
| Age To |
65.00 Year(s) |
| Gender |
Both |
| Details |
Patients having symptoms like radiating pain, tingling, numbness in unilateral upper limb from at least 4 months.
Patients showing either positive compression test, Spurling’s test, Upper limb nerve tension test or distraction test with ipsilateral cervical rotation that is less than 60-degrees
Patients having more than or equal to 3 on NPRS
|
|
| ExclusionCriteria |
| Details |
Traumatic neck injury, recent fracture (less than 6 months) and dislocation.
Tumour-causing cervical radiculopathy.
Diagnosed cases of osteoporosis
Circulatory Disturbances
Diagnosed cases of vestibular impairment demonstrated by vertigo or dizziness
Hypermobility of cervical spine
Pregnancy
Any congenital deformity of spine like torticollis
A history of cervical surgeries in the last 10 years
Bilateral cervical radiculopathies
|
|
|
Method of Generating Random Sequence
|
Other |
|
Method of Concealment
|
Sequentially numbered, sealed, opaque envelopes |
|
Blinding/Masking
|
Participant Blinded |
|
Primary Outcome
|
| Outcome |
TimePoints |
1. Numeric Pain Rating Scale
2. Inclinometer for cervical range of motion
3. Northwick Park Pain Questionnaire
4. The disability of Arm, Shoulder and Hand |
All the outcome measures will be measured on pre intervention (day 1) and (day 6) post intervention |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| NIL |
NIL |
|
|
Target Sample Size
|
Total Sample Size="40"
Sample Size from India="40"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
26/09/2025 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="0"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Yet Recruiting |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
This study will compare two physiotherapy techniques for people with neck and arm pain due to pinched nerves (cervical radiculopathy).
One technique is nerve exercises (neural mobilization) that help the nerve move freely.
The other is muscle and tissue release (myofascial release) that reduces tightness in the neck and arm.
Adults aged 32–65 years with one-sided neck and arm pain will take part for 2 weeks.
We will check changes in pain, neck movement, and daily function using standard questionnaires and tools.
The study may help find better treatment options for neck and arm pain caused by pinched nerves. |