| CTRI Number |
CTRI/2025/10/095781 [Registered on: 09/10/2025] Trial Registered Prospectively |
| Last Modified On: |
07/10/2025 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Drug
Homeopathy |
| Study Design |
Single Arm Study |
|
Public Title of Study
|
Treatment Of Irritable Bowel Syndrome Using Murphy Repertory |
|
Scientific Title of Study
|
Clinical Utility of Homoeopathic Medical Repertory by Dr. Robin Murphy in cases of Irritable Bowel Syndrome using IBS-SSS |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Muskaan Bellani |
| Designation |
Md Scholar - Homeopathic Repertory & Case Taking |
| Affiliation |
Anand Homeopathic Medical College And Research Institute |
| Address |
Room No 210 - 1st Floor, Department Of Homeopathic Repertory And Case Taking, Anand Homoeopathic Medical College And Research Institute, Opp Sardar Baug, Bhalej Road
Anand
GUJARAT
388001
India |
| Phone |
7574923844 |
| Fax |
|
| Email |
muskaanbellani@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Annapurna Mistry |
| Designation |
Md Homeopathy Professor Of Homeopathic Repertory And Case Taking |
| Affiliation |
Anand Homeopathic Medical College and Research Institute |
| Address |
Room No 213 , 1st Floor, Department Of Homeopathic Repertory And Case Taking, Anand Homeopathic Medical College and Research Institute, Nr Sardar Baug, Bhalej Road
Anand
GUJARAT
388001
India |
| Phone |
635971655 |
| Fax |
|
| Email |
dranmistry@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
DR ANNAPURNA MISTRY |
| Designation |
ASSOCIATE PROFESSOR |
| Affiliation |
ANAND HOMEOPATHIC MEDICAL COLLEGE AND RESEARCH INSTITUTE |
| Address |
ANAND HOMEOPATHIC MEDICAL COLLEGE AND RESEARCH INSTITUTE
Opp SARDAR BAUGH , BHALEJ ROAD , ANAND
Anand
GUJARAT
388001
India |
| Phone |
635971655 |
| Fax |
|
| Email |
dranmistry@gmail.com |
|
|
Source of Monetary or Material Support
|
| Anand Homeopathic And General Hospital, Opp Sardar Baug, Nr New Bus Stand, Bhalej Road - 388001, Anand, Gujarat, India |
|
|
Primary Sponsor
|
| Name |
MUSKAAN BELLANI |
| Address |
A8/31 sant kanwar colony warashiya
Vadodara,390006 |
| Type of Sponsor |
Other [SELF] |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| MUSKKAAN BELLANI |
Anand Homeopathic And General Hospital |
Ground Floor, Department of Medicine OPD No 1 Room No 1, Opp Sardar Baug, Bhalej Road - 388001
Anand
GUJARAT |
7574923844
muskaanbellani@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| INSTITUTIONAL ETHICS COMMITTEE , ANAND HOMOEOPATHIC MEDICAL COLLEGE AND RESEARCH INSTITUTE |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: K582||Mixed irritable bowel syndrome, (2) ICD-10 Condition: K580||Irritable bowel syndrome with diarrhea, (3) ICD-10 Condition: K581||Irritable bowel syndrome with constipation, (4) ICD-10 Condition: K588||Other irritable bowel syndrome, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Intervention |
HOMOEOPATHIC MEDICINE |
Oral administration of homoeopathic medicine selected after repertorisation with the aid of homoeopathic medical repertory by Dr Robin Murphy. Repetition of medicine and potency of medicine will be selected on the basis of susceptibility of patient and severity of complaint. Follow up every 15 days or earlier if required. 30 ,200,1M potency will be prescribed in individualised medicine |
| Comparator Agent |
NOT APPLICABLE as there is no comparator agent |
NOT APPLICABLE |
|
|
Inclusion Criteria
|
| Age From |
15.00 Year(s) |
| Age To |
65.00 Year(s) |
| Gender |
Both |
| Details |
1. Patients diagnosed as per ROME’S IV Criteria with IBS, with no major
complications or concurrent severe illnesses. |
|
| ExclusionCriteria |
| Details |
1. Patients with anatomical abnormalities , inflammatory bowel diseases,
malignancies, or requiring urgent surgical interventions.
2.Subjects under 15 years and above 65 years will be excluded from studies
3.Pregnant or lactating women |
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Open Label |
|
Primary Outcome
|
| Outcome |
TimePoints |
USEFULLNESS OF HOMOEOPATHIC MEDICAL REPERTORY BY DR ROBIN MURPHY IN CASES OF IBS |
BASELINE 0 WEEK,4TH WEEK , 3RD MONTH , 6TH MONTH , 9TH MONTH |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
1.IMPROVEMENT IN QUALITY OF LIFE OF PATIENT
Improvemnt in IBSSS Score
2.IDENTIFIFICATION OF EFFECTIVE HOMOEOPATHIC REMEDIES DURING SELECTION OF RUBRICS FROM HOMOEOPATHIC MEDICAL REPERTORY BY DR ROBIN MURPHY .
|
BASELINE 0 WEEK,4TH WEEK , 3RD MONTH , 6TH MONTH , 9TH MONTH |
|
|
Target Sample Size
|
Total Sample Size="50"
Sample Size from India="50"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
Phase 2 |
|
Date of First Enrollment (India)
|
21/10/2025 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="6"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
This study will evaluate the role of individualized homoeopathic treatment in patients with Irritable Bowel Syndrome (IBS). Patients diagnosed with IBS using the Rome IV criteria will be treated with remedies selected through Murphy’s Homoeopathic Repertory. The effectiveness of treatment will be assessed using the IBS Symptom Severity Score (IBS-SSS). A total of 50 patients between 15–65 years will be included, and follow-up will be done weekly for 18 months. The study aims to measure improvement in symptoms, quality of life, and patient satisfaction, while also identifying commonly indicated homoeopathic remedies for IBS.
|