Study title: Management of Recurrent Retroperitoneal Sarcomas:  A retrospective study from a Tertiary Cancer Center.

Short title: Management of Recurrent Retroperitoneal Sarcomas

Type of study: Retrospective observational study

Retroperitoneal Sarcomas (RPS) are a complex heterogenous group of relatively uncommon tumors. Owing to their complexity and rarity the optimal management of these tumours is restricted to very few dedicated high-volume centers. As a result, a large number of patients present to our center with recurrent disease. Additionally, even after optimal treatment done at high-volume centers these tumors have a high propensity for recurrence.

While there have been substantial milestones achieved in the treatment of primary RPS resulting in development of collaborative efforts, both at institutional level (in the form of dedicated RP clinics) and at internation level (in the for Transatlantic retroperitoneal sarcoma working group guidelines), there is substantial dearth of literature and consensus on the optimal strategies for management of recurrent RPS (rec RPS). It is therefore crucial to audit the outcomes of patients undergoing surgical treatment for rec RPS, in order to identify the optimal treatment strategies in terms of extent and number of re-resections and adjuvant treatment options for these patients.

This is a single center retrospective study, aims to evaluate the outcomes of rec RPS sarcomas (RPS). The results of this study are expected to answer this important question of benefit and futility of surgical excision in patients with multiple local recurrences of RPS and thereby guide optimal treatment strategies.