CTRI

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CTRI Number

CTRI/2025/09/094584 [Registered on: 11/09/2025] Trial Registered Prospectively

Last Modified On:

12/09/2025

Post Graduate Thesis

Yes

Type of Trial

Interventional

Type of Study

Ayurveda

Study Design

Randomized, Parallel Group Trial

Public Title of Study

To see the effect of Kanadi Churna Pratisarana and Madhu mishrit Panchvalkal Kwath gandush in Dantveshta (Pyorrhoea alveolaris)

Scientific Title of Study

Comparative Clinical Evaluation of Kanadi Churna Pratisarana and Madhu mishrit Panchvalkal Kwath gandush in Dantveshta (Pyorrhoea alveolaris)

Trial Acronym

NIL

Secondary IDs if Any

Secondary ID	Identifier
NIL	NIL

Details of Principal Investigator or overall Trial Coordinator (multi-center study)

Name	Ishu Kumari
Designation	PGScholar
Affiliation	Patanjali Bhartiya Ayurvigyan Evam Anusandhan Sansthan
Address	Dental OPD , OPD3 , department of Shalakya Tantra, Patanjali Ayurved Hospital, Patanjali Bhartiya Ayurvigyan Evam Anusandhan Sansthan phase 1, roorkee Road, haridwar, Uttarakhand, India 2409405 Hardwar UTTARANCHAL 249405 India
Phone	9639047868
Fax
Email	ishu.1997.kumari@gmail.com

Details of Contact Person
Scientific Query

Name	Prof Jyoti Gupta
Designation	Professor
Affiliation	Patanjali Bhartiya Ayurvigyan Evam Anusandhan Sansthan
Address	OPD 3 , department of Shalakya Tantra, Patanjali Ayurved Hospital, Patanjali Bhartiya Ayurvigyan Evam Anusandhan Sansthan phase 1, roorkee Road, Hardwar UTTARANCHAL 249405 India
Phone	9997907340
Fax
Email	jyotiguptania@gmail.com

Details of Contact Person
Public Query

Name	Prof Jyoti Gupta
Designation	Professor
Affiliation	Patanjali Bhartiya Ayurvigyan Evam Anusandhan Sansthan
Address	OPD 3 , department of Shalakya Tantra, Patanjali Ayurved Hospital, Patanjali Bhartiya Ayurvigyan Evam Anusandhan Sansthan phase 1, roorkee Road, UTTARANCHAL 249405 India
Phone	9997907340
Fax
Email	jyotiguptania@gmail.com

Source of Monetary or Material Support

Patanjali Bhartiya Ayurvigyan Evam Anusandhan Sansthan

Primary Sponsor

Name	Patanjali Bhartiya Ayurvigyan Evam Anusandhan Sansthan
Address	Patanjali Bhartiya Ayurvigyan Evam Anusandhan Sansthan, haridwar , Uttarakhand, India 249405
Type of Sponsor	Private medical college

Details of Secondary Sponsor

Name	Address
NIL	NIL

Countries of Recruitment

India

Sites of Study

No of Sites = 1
Name of Principal Investigator	Name of Site	Site Address	Phone/Fax/Email
Dr Ishu Kumari	Patanjali Bhartiya Ayurvigyan Evam Anusandhan Sansthan	Department Of Shalakya Tantra OPD 3,Department Of Dental patanjali Ayurved Hospital, Patanjali Bhartiya Ayurvigyan Evam Anusandhan Sansthan,phase 1, Roorkee road, Haridwar,Uttaranchal Hardwar UTTARANCHAL	9639047868 ishu.1997.kumari@gmail.com

Details of Ethics Committee
Modification(s)

No of Ethics Committees= 1
Name of Committee	Approval Status
Institutional Ethical Committee, Patanjali Bhartiya Ayurvigyan Evam Anusandhan Sansthan, haridwar	Approved

Regulatory Clearance Status from DCGI

Status

Not Applicable

Health Condition / Problems Studied

Health Type	Condition
Patients	(1) ICD-10 Condition:R688\|\|Other general symptoms and signs. Ayurveda Condition: DANTAVESHTAKAH,

Intervention / Comparator Agent

sno	Intervention/Comparator	Type	Drug-Type	Procedure Name	Details
1	Comparator Arm	Procedure	-	pratisAraNam, प्रतिसारणम्	(Procedure Reference: Yogaratnakar, Procedure details: Using index finger, gentle application & rubbing of Kanadi churna on gum area for 10 minutes twice a day.) (1) Medicine Name: Kanadi churna, Reference: Yogaratnakar, Route: Topical, Dosage Form: Churna/ Powder, Dose: 3(g), Frequency: bd, Duration: 15 Days
2	Comparator Arm	Procedure	-	gaNDUShaH, गण्डूषः	(Procedure Reference: Yogaratnakar, Procedure details: Holding 50ml of Madhu Mishrit Panchvalkal Kwath in oral cavity without gargling until patient develops watery discharge from nose & eyes. ) (1) Medicine Name: Madhu Mishrit Panchvalkal Kwath, Reference: Yogaratnakar, Route: Oral, Dosage Form: Kwatha/Kashaya, Dose: 50(ml), Frequency: bd, Duration: 15 Days
3	Intervention Arm	Drug	Classical		(1) Medicine Name: Kanadi Churna, Reference: Yogaratnakar, Route: Topical, Dosage Form: Churna/ Powder, Dose: 3(g), Frequency: bd, Bhaishajya Kal: Abhakta, Duration: 15 Days, anupAna/sahapAna: No, Additional Information: - (2) Medicine Name: Madhu Mishrit Panchvalkal Kwath, Reference: Yogaratnakar, Route: Oral, Dosage Form: Kwatha/ Kashaya, Dose: 50(ml), Frequency: bd, Bhaishajya Kal: Abhakta, Duration: 15 Days, anupAna/sahapAna: No, Additional Information: -

Inclusion Criteria

Age From	20.00 Year(s)
Age To	60.00 Year(s)
Gender	Both
Details	1. The patients presenting with classical features of Dantveshta such as bleeding gums, mobile tooth, pus discharge from gums. 2. Age group between 20-60yrs.

ExclusionCriteria

Details

1. patient below 20yrs of age and above 60yrs
2. pregnant or lactating females.
3. patients with some mental disability.
4. Other types of Dantmulgat rogas.

Method of Generating Random Sequence

Computer generated randomization

Method of Concealment

On-site computer system

Blinding/Masking

Open Label

Primary Outcome

Outcome	TimePoints
Subjective parameters will be assessed- 1. Raktasrava(blood gums) 2.Chaladanta(Tooth mobility)	0,2 weeks,4 weeks,6 weeks

Secondary Outcome

Outcome	TimePoints
1.Durgandhya(offensive odous or halitosis) 2. Puyasrava(Pus discharge)	0,2 weeks,4 weeks,6 weeks

Target Sample Size

Total Sample Size="60"
Sample Size from India="60"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials"

Phase of Trial

N/A

Date of First Enrollment (India)

25/09/2025

Date of Study Completion (India)

Applicable only for Completed/Terminated trials

Date of First Enrollment (Global)

Date Missing

Date of Study Completion (Global)

Applicable only for Completed/Terminated trials

Estimated Duration of Trial

Years="1"
Months="8"
Days="0"

Recruitment Status of Trial (Global)

Not Applicable

Recruitment Status of Trial (India)

Not Yet Recruiting

Publication Details

N/A

Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?

Response - NO

Brief Summary

In this trial we are selecting the patients of Dantveshta in which we will do the intervention in two groups- 30 patients in each group. In one group, we will intervene with ayurvedic therapeutic procedure of Pratisarana with kanadi churna , whereas in other group we will intervene with another ayurvedic therapeutic procedure of gandush with Madhu mishrit panchvalakal kwath. Assessment will be done on the basis of subjective parameters and scoring will be done before and after the treatment.