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CTRI Number  CTRI/2025/09/094945 [Registered on: 16/09/2025] Trial Registered Prospectively
Last Modified On: 08/09/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Physiotherapy (Not Including YOGA) 
Study Design  Other 
Public Title of Study   Virtual reality training to improve upper limb movement in stroke patients. 
Scientific Title of Study   Virtual reality training for upper limb rehabilitation in subacute stroke patients: A Quasi experimental study on improving motor function.  
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  JAGADISH KUMAR M 
Designation  PG RESIDENT 
Affiliation  College of Physiotherapy, Sri Ramakrishna Institute of Paramedical Sciences. 
Address  3rd floor, 2nd room, College of Physiotherapy, Sri Ramakrishna Institute of Paramedical Sciences, 395, Sarojini Naidu Road, Sidhapudur, Coimbatore-641044, Tamil Nadu.

Coimbatore
TAMIL NADU
641044
India 
Phone  9585886041  
Fax    
Email  jagadishkumarm0@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  PORKODI R 
Designation  MPT(Neurology) 
Affiliation  College of Physiotherapy, Sri Ramakrishna Institute of Paramedical Sciences. 
Address  3rd floor, 2nd room, College of Physiotherapy, Sri Ramakrishna Institute of Paramedical Sciences, 395, Sarojini Naidu Road, Sidhapudur, Coimbatore-641044, Tamil Nadu.

Coimbatore
TAMIL NADU
641044
India 
Phone  09443820164  
Fax    
Email  porkodi.mpt@gmail.com  
 
Details of Contact Person
Public Query
 
Name  PORKODI R 
Designation  MPT (Neurology) 
Affiliation  College of Physiotherapy, Sri Ramakrishna Institute of Paramedical Sciences. 
Address  3rd floor, 2nd room, College of Physiotherapy, Sri Ramakrishna Institute of Paramedical Sciences, 395, Sarojini Naidu Road, Sidhapudur, Coimbatore-641044, Tamil Nadu.

Coimbatore
TAMIL NADU
641044
India 
Phone  09443820164  
Fax    
Email  porkodi.mpt@gmail.com  
 
Source of Monetary or Material Support  
Neuro rehabilitation center, Sri Ramakrishna Multi Speciality Hospital, 395, Sarojini Naidu Road, Sidhapudur, Coimbatore-641044, Tamil Nadu, India. 
 
Primary Sponsor  
Name  JAGADISH KUMAR M 
Address  3RD FLOOR, 2ND ROOM, COLLEGE OF PHYSIOTHERAPY, SRI RAMAKRISHNA INSTITUTE OF PARAMEDICAL SCIENCES, 395 SAROJINI NAIDU ROAD, SIDHAPUDUR, COIMBATORE- 641044 Coimbatore TAMIL NADU 641044 India  
Type of Sponsor  Other [SELF] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
PORKODI R  Sri Ramakrishna Multi Speciality Hospital  3rd floor, 2nd room, College of Physiotherapy, Sri Ramakrishna Institute of Paramedical Sciences, 395, Sarojini Naidu Road, Sidhapudur, Coimbatore- 641044.
Coimbatore
TAMIL NADU 
09443820164

porkodi.mpt@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
SRI RAMAKRISHNA HOSPITAL ETHICAL COMMITTEE  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: I693||Sequelae of cerebral infarction,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Group A: Virtual Reality with Conventional therapy.  15 repetitions for each exercises for 30 minutes per day, 5 days per week per session for about 6 weeks. Shoulder Flexo-extension, Shoulder Abducto-adduction, Shoulder Rotations, Elbow flexo-extension, Wrist Flexo- extension and range of motion exercises.  
Comparator Agent  Group B: Conventional therapy alone.  15 repetitions for each exercises for 30 minutes per day, 5 days per week per session for about 6 weeks. Shoulder, elbow and wrist range of motion exercises. 
 
Inclusion Criteria  
Age From  40.00 Year(s)
Age To  55.00 Year(s)
Gender  Both 
Details  Participant is aged 40 – 55 yrs.
Both males and females,
Both ischemic and haemorrhagic types of stroke,
Left MCA stroke is included,
A first episode of unilateral stroke with hemiparesis,
Stroke duration less than 6 months and more than 1 month,
Function in sitting test (score greater than 40),
Medically stable enough to participate in active rehabilitation,
Upper extremity motor deficits (Brunnstrom stage for upper extremity 4). 
 
ExclusionCriteria 
Details  Uncontrolled blood pressure or angina,
Cognitive impairment (defined as score LESS THAN 24 MMSE),
Problems with auditory or visual functioning,
Fracture and joint dislocation,
Severe hemineglect,
Pusher’s syndrome,
History or current diagnoses of any other neurological OR psychiatric conditions. 
 
Method of Generating Random Sequence   Not Applicable 
Method of Concealment   Not Applicable 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
Fugl-Meyer Assessment - Upper Extremity   Pre test of individual participant will be assessed at baseline and post test will be assessed after 4-6 months 
 
Secondary Outcome  
Outcome  TimePoints 
nil  nil 
 
Target Sample Size   Total Sample Size="30"
Sample Size from India="30" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   19/09/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  
The Global Burden of Disease Study suggested Stroke is the second leading cause of death globally and the third leading cause of premature death and disability as measured in Disability Adjusted Life Years (DALY). Upper limb motor impairment is a common disability in stroke. Afflicted patients need to undergo therapeutic exercises to restore motor function and independence. Virtual Reality (VR) is a technology that creates a simulated environment, allowing users to feel like they are in a different place or world.  Virtual reality (VR) technology has emerged as a new technique in neurorehabilitation. It enables users to control and interact with the game console without the need to touch a game controller, through a natural gesture-based user interface. The device comes with an RGB camera and a depth sensor, which in combination provides full- body three dimensional motion capture capabilities and gesture recognition. . The aim is to investigate the effectiveness of virtual reality training on improving upper limb motor function as measured by the  Fugl Meyer Assessment for Upper Extremity. The objective is to evaluate the effectiveness of virtual reality training on upper limb motor function in subacute stroke patients. Methodology: A quasi experimental study was conducted involving both males and females in subacute stroke patients aged 40–55 years with mild to moderate upper limb motor impairment will be divided into two groups: Group A will receive VR-based training along with conventional therapy, while Group B will receive conventional therapy alone (Range of motion exercises). The intervention will last up to 6 weeks with 5 sessions per week. Motor function will be assessed using the Fug Meyer Assessment for Upper Extremity before and after the intervention.
Results: Pre-test and post-test intervention assessment may indicate significant improvements in both groups but greater improvement in group A.
Expected Outcomes: It is expected that the combination of VR and conventional therapy will result in greater improvements in upper limb motor function compared to conventional therapy alone.
Conclusion: If effective, VR-based training could be integrated into routine stroke rehabilitation to enhance motor recovery, patient motivation and cost-effectiveness.
 
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