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CTRI Number  CTRI/2026/01/101572 [Registered on: 19/01/2026] Trial Registered Prospectively
Last Modified On: 18/01/2026
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Yoga & Naturopathy 
Study Design  Single Arm Study 
Public Title of Study   A Clinical Study To Evaluate the Efficacy Of Vaman Dhauti (Kunjal Kriya) In The Management Of patient with Urdhwaga Amlapitta With Special Refference To Hyperacidity 
Scientific Title of Study   A Clinical Study Of Efficacy Of Vaman Dhauti (Kunjal Kriya) On Urdhwaga Amlapitta W.S.R. To Hyperacidity 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr shubham Yashwant Maske 
Designation  PG scholar 
Affiliation  Bhausaheb Mulak Ayurved Mahavidyalaya And Research Hospital ,Nandanvan ,Nagpur 
Address  OPD,Dept. Of Swasthavritta and Yoga,Bhausaheb Mulak Ayurveda Mahavidyalaya and Research Hospital,Nandanvan,Nagpur

Nagpur
MAHARASHTRA
440024
India 
Phone  7397801857  
Fax    
Email  shubham95maske@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Madhavi V Rehpade 
Designation  H.O.D. Dept. Of Swasthavritta And Yoga 
Affiliation  Bhausaheb Mulak Ayurved Mahavidyalaya And Research Hospital ,Nandanvan ,Nagpur 
Address  OPD,Dept. Of Swasthavritta and Yoga,Bhausaheb Mulak Ayurveda Mahavidyalaya and Research Hospital,Nandanvan,Nagpur

Nagpur
MAHARASHTRA
440024
India 
Phone  9422146204  
Fax    
Email  madhavi309@yahoo.co.in  
 
Details of Contact Person
Public Query
 
Name  Dr Madhavi V Rehpade 
Designation  H.O.D. Dept. Of Swasthavritta And Yoga 
Affiliation  Bhausaheb Mulak Ayurved Mahavidyalaya And Research Hospital ,Nandanvan ,Nagpur 
Address  OPD,Dept. Of Swasthavritta and Yoga,Bhausaheb Mulak Ayurveda Mahavidyalaya and Research Hospital,Nandanvan,Nagpur

Nagpur
MAHARASHTRA
440024
India 
Phone  9422146204  
Fax    
Email  madhavi309@yahoo.co.in  
 
Source of Monetary or Material Support  
OPD of swashtyarakshan dept,Bhausaheb Mulak Ayuevedic medical college,nandanvan,Nagpur,Maharashtra,India,440024 
 
Primary Sponsor  
Name  Bhausaheb Mulak Ayurved Mahavidyalaya And Research Hospital ,Nandanvan ,Nagpur 
Address  Bhausaheb Mulak Ayurved Mahavidyalaya And Research Hospital Nandanvan Nagpur 
Type of Sponsor  Private medical college 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Shubham Yashwant Maske  Bhausaheb Mulak Ayurved Mahavidyalaya And Research Hospital   OPD,Dept.Of Swasthavritta And Yoga
Nagpur
MAHARASHTRA 
9284632078

shubham95maske@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
BORS Committee of Institute,BMAM,Nagpur  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition:K219||Gastro-esophageal reflux disease without esophagitis. Ayurveda Condition: AMLAPITTAM, (2) ICD-10 Condition:8||Other Procedures. Ayurveda Condition: AMLAPITTAM,  
 
Intervention / Comparator Agent  
snoIntervention/ComparatorTypeDrug-TypeProcedure NameDetails
1Intervention ArmProcedure-Vaman Dhauti (Procedure Reference: Gherand Samhita 1/38, Procedure details: Vaman Dhauti (kunjal kriya) Twice a Week)
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  40.00 Year(s)
Gender  Both 
Details  1.Age Group - 18 to 40 Years
2. Patient who have symptoms of Urdhwaga Amlapitta as mentioned in Ayurvedic texts like Avipaka, Utklesha,Chhardi,TiktaamlaUdgar,Aruchi,Hrud-Kanthdah, Gaurav ,Udarshool.
3.Irrespective of gender, caste , religion and socio-economic class.
4.Patients Co-operative for Trial. 
 
ExclusionCriteria 
Details  1)Patient not willing to participate in the trial.
2)Patients below the age of 18 years and above 40 years.
3)Associated with any serious gastroenterological disease like Gastric ulcer
,Perforated ulcer,Duodenal ulcer,Cancer of any grade of oesophagus,Strictures of oesophagus,Abdominal Koch’s etc.(any surgical coindition),
4)Pregnant ladies and lactating mother.
5)Associated with any other serious systemic disease or complication like Diabetic melitus and insipidus, hypertension
6)Drug induced amlapitta. 
 
Method of Generating Random Sequence   Not Applicable 
Method of Concealment   Case Record Numbers 
Blinding/Masking   Open Label 
Primary Outcome  
Outcome  TimePoints 
To study the efficacy of Vaman Dhauti (Kunjal Kriya) on Urdhwaga Amlapitta symptoms like Avipaka,Utklesha,Chhardi,TiktaamlaUdgar,Aruchi,HrudKanthdah, Gaurav,Udarshool.  1 Month 
 
Secondary Outcome  
Outcome  TimePoints 
1)To study the efficacy of Vaman Dhauti (Kunjal Kriya) on Urdhwaga Amlapitta.
2)To study Amlapitta disease as per Ayurvedic and Modern aspects.
3) To Study the Vaman Dhauti procedure. 
At 0th,7th,15th,21th,30th Day 
 
Target Sample Size   Total Sample Size="47"
Sample Size from India="47" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   Phase 3 
Date of First Enrollment (India)   15/02/2026 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

INTRODUCTION: Ayurveda is a unique boon to the community since  ancient years. The science with a history of several thousand years has very strong principles on which it has developed. Ayurveda has mainly two principle objectives .First maintenance  and promotion of health and Secondly pevention and cure from disease. Swasthavritta is the branch of ayurveda that deals with  the  pevention of any disease with the holistic approach by healthy lifestyle, diet,hygiene, daily regimen and yoga.  

                  The period of 21st century is regarded as the era of fast technology and tough competition. The man of this era is becoming prey to series of life style disorder which are much more bothering than the infective diseases. The altered life style activities like fried food, night shift duties, mental stress, addictions etc. are the major risk factors for the lifestyle disorders.Urdhwaa Amlapitta i.e .Hyperacidity is one of them.                                         

Urdhwaga Amlapitta, also known as Hyperacidity is generally a result of incorrect and irregular eating habits and it is one of the common ailments seen in many people.Hurry,Worry and Curry are the three main reasons for the amlapitta disease. In India reveals that 25% of the people are suffering from this disorder. Stomach contains acids that help in the process of digestion of food, When the level of these digestive acids increases, it starts to erosion of the mucus lining faster, and the stomach muscles become exposed leading to burning sensation and this condition is known as hyperacidity.

                              According to Ayurveda, excess consumption of Pitta Prakopakara Ahara, Vihara leads to Amlata, Dravata, and Vriddhi of Pitta causing Shuktata of Pitta.The all above mentioned causes leads to imbalance of the Shareerika Doshas Vata, Pitta & Kapha in turn create Agnimandya & due to improperly metabolized and get convert into Shuktata (vitiated liquid acid) and this gets situated in Amashaya which is called as Amlapitta. The disease mainly caused by improper dietetic pattern, mental stress and strain which is related to our digestion.

Vamana Dhauti one of the yogic Shatkarmas  cleans the entire digestive tract and removes  excess acid, bile, mucus, toxins and restores the natural balance of the stomach chemical composition. By considering the above factors Management of Amlapitta aims at minimizing the symptoms, correcting the Agni, Optimize the quality of life and reduces the risk of developing co-morbidities. Hence Ayurveda and Yogic procedures offers respectively as treatment modalities for resisting this types of disorders.This technique is also known as Gajkarni.

RATIONAL OF STUDY :       The digestive system plays an important role for the absorption of nutrients and the nourishment of overall body. the factors such as stress, lack of sleep, use of antibiotics, NSAIDs, improper water intake and poor dietary habits impaired digestive systems and cause the gastrointestinal disorders[GIDS] the severity of GID ’s varies as per disease types some like indigestion are mild while Acid peptic diseases such as hyperacidity, gastro esophageal Reflux disease [GERD], gastric and duodenal ulcer are life threatening conditions. It may cause malignant conditions like adenocarcinoma and other stomach cancer.About 7 lakh people died in 2002 due to stomach cancer. Amlapitta can be correlated with Acid Peptic Disorders which comprises of Hyperacidity,Gastro-Oesophageal Reflux Disease, Gastritis, Functional Dyspepsia described in modern science.                                                                                                                                                                                                                                                                                                                                                                                                 In Gherand samhita and hathyog pradipika there is one wander ‘Vaman Dhauti suddhi kriya’ given and advised it’s Vaman Dhauti in amashaygat roga. Although there are treatments available in medical sciences for Amlapitta, no drug ensures relief. So there is need for safe, effective and easily perfrom Vaman Dhauti (Kunjal Kriya). 

Hence the study titled as "A Clinical Study Of Efficacy Of Vaman Dhauti (Kunjal Kriya) In The Management Of Amlapitta W.S.R. To Hyperacidity.”

OBJECTIVES:   

 Primary Objective-

To study the efficacy of Vaman Dhauti (Kunjal Kriya)  on Urdhwaga  Amlapitta.

             Secondary Objectives-

Ø To study the  Amlapitta disease as per Ayurveda Literature .

Ø To study the Hyperacidity as per Modern Literature.

                To study the Vaman Dhauti (Kunjal Kriya) procedure.

ASSESMENT CRITERIA:

Subjective parameters

Based on sign & Symptoms of Urdhwag Amlapitta Amlapitta Symptoms Rating Scale (ASRS)

1. Avipaka  (Indigestion)

2.  Utklesha  (Nausea)

3. Chhardi  (Vomiting)

4. Tiktaamla Udgar (Bitter & Sour Belching)

5. Aruchi (Anorexia)

6. Hrud-Kanthdah (Burning sensation in heart and throat)

7. Gaurav  (Heaviness)

8.    Udarshool (Stomachache)


Overall Effect of Therapy (Overall Assessment Criteria) :-

Overall assessment will be done by following  -

1. Not cured - No improvement in subjective Criteria

2. Improved - Improvement in Subjective criteria

3. Cured - Improvement in Subjective criteria


Excellent

0

100% Relief in sign & symptoms

Very mild

1-7

75-99% Relief in sign & symptoms

Mild

8-14

50- 75% Relief in sign & symptoms

Moderate

15-21

25-50% Relief in sign & symptoms

Severe (Infective)

22-28

0-25% Relief in sign & symptoms.

Amlapitta Symptoms Rating Scale (ASRS)
Minimum Score – 0
Maximum Score – 28
 
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