| CTRI Number |
CTRI/2025/09/093968 [Registered on: 01/09/2025] Trial Registered Prospectively |
| Last Modified On: |
30/08/2025 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Drug
Homeopathy |
| Study Design |
Randomized, Parallel Group, Active Controlled Trial |
|
Public Title of Study
|
Evaluating the Role of Homeopathic Constitution Chapter from Murphys Repertory in managing type 2 Diabetes Mellitus |
|
Scientific Title of Study
|
An Interventional Study to Assess Clinical Relevance of Chapter Constitution From Homoeopathic Medical Repertory By Robin Murphy In Cases of Type 2 Diabetes Mellitus |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Meera Shah |
| Designation |
Professor Head Of Department Of Homoeopathic Repertory And Case Taking |
| Affiliation |
Dr V H Dave Homoeopathic Medical College |
| Address |
Room no 4, Department of Medicine, Dr V H Dave Homoeopathic Medical College and Smt S I Patel (I) Homoeopathic Hospital Hahnemann House Amul Dairy Road Anand Gujarat
Anand
GUJARAT
388001
India |
| Phone |
9898692003 |
| Fax |
|
| Email |
dr.meerashah@yahoo.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Meera Shah |
| Designation |
Professor Head Of Department Of Homoeopathic Repertory And Case Taking |
| Affiliation |
Dr V H Dave Homoeopathic Medical College |
| Address |
Room no 4, Department of Medicine, Dr V H Dave Homoeopathic Medical College and Smt S I Patel (I) Homoeopathic Hospital Hahnemann House Amul Dairy Road Anand Gujarat
Anand
GUJARAT
388001
India |
| Phone |
9898692003 |
| Fax |
|
| Email |
dr.meerashah@yahoo.com |
|
Details of Contact Person
Public Query
|
| Name |
Dr Renuben Chavda |
| Designation |
PG Scholar |
| Affiliation |
Dr V H Dave Homoeopathic Medical College and Smt S I Patel (I) Homoeopathic Hospital |
| Address |
Room no 4, Department of Medicine, Dr V H Dave Homoeopathic Medical College and Smt S I Patel (I) Homoeopathic Hospital Hahnemann House Amul Dairy Road Anand Gujarat
Anand
GUJARAT
388250
India |
| Phone |
9265402928 |
| Fax |
|
| Email |
renuchavda543@gmail.com |
|
|
Source of Monetary or Material Support
|
| Dr V H Dave Homoeopathic Medical College and Smt S I Patel (I) Homoeopathic Hospital Hahnemann House Amul Dairy Road Anand Gujarat 388001 |
|
|
Primary Sponsor
|
| Name |
Dr Renuben Chavda |
| Address |
149 Sapna Bhavan Sukhini Muvadi,Ta. Galteshwar, dist. Kheda,Ambav, Pin code 388250 |
| Type of Sponsor |
Other [Self] |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Renuben Chavda |
Smt S I Patel (I) Homoeopathic Hospital |
Department Of Medicine Dr V H Dave Homoeopathic Medical College and Smt S I Patel (I) Homoeopathic Hospital Hahnemann House Amul Dairy Road Anand Gujarat
Anand
GUJARAT |
9265402928
renuchavda543@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| IEC-VHDHMC |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: E118||Type 2 diabetes mellitus with unspecified complications, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Comparator Agent |
Individual Homoeopathic Medicine |
The medicine will be prescribed after doing repertorization with the use of Murphy Repertory and final choice will be made with the help of Homeopathic Materia Medica.The potencies 6C,30C, 200C and 1M will be selected depending upon the susceptibility of the patient.Oral administration will be chosen.The remedy will be repeated as per the requirement of case. Total duration of study is of 9 months. |
| Intervention |
Individual Homoeopathic Medicine |
The medicine will be prescribed after doing repertorization with the use of rubrics from constitutional chapter of Murphy Repertory and final choice will be made with the help of Homeopathic Materia Medica.The potencies 6C,30C, 200C and 1M will be selected depending upon the susceptibility of the patient.Oral route of administration will be chosen, remedy will be repeated as per the requirement of case. Total duration of study is of 9 motnhs |
|
|
Inclusion Criteria
|
| Age From |
35.00 Year(s) |
| Age To |
70.00 Year(s) |
| Gender |
Both |
| Details |
Diagnosed cases of type 2 Diabetes Mellitus of both sexes will be included.
Age/Gender: The cases between 35 to 70 years will be selected irrespective of gender. |
|
| ExclusionCriteria |
| Details |
Cases of type 1 Diabetes Mellitus.
Patient having diabetic complications (e.g., Nephropathy, Retinopathy)
Patient who requires emergency medical treatment.
Cases with irreversible pathology will be excluded from this study.
Female cases those are having pregnancy will be excluded.
The cases which do not match with symptoms of constitution chapter, e.g. Local disease, one sided disease.
Patients not taking medicine as per directions. |
|
|
Method of Generating Random Sequence
|
Other |
|
Method of Concealment
|
Other |
|
Blinding/Masking
|
Open Label |
|
Primary Outcome
|
| Outcome |
TimePoints |
| Monarch score |
At first follow up which will be at 2 weeks and at the end of treatment |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| FBS,PP2BS,HBA1C |
At the beginning of treatment, at the end of 3 months and 6 months |
|
|
Target Sample Size
|
Total Sample Size="50"
Sample Size from India="50"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
Phase 3 |
|
Date of First Enrollment (India)
|
01/10/2025 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="0"
Months="9"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
The Constitution chapter in the Homoeopathic Medical Repertory By Robin Murphy is important for several reasons in homeopathic case taking and remedy selection. Constitutional analysis involves assessing the overall physical, mental and emotional makeup of a person. This allows a homeopath to go beyond superficial symptoms and find a deeper acting remedy that suits the patient as a whole. Diabetes Mellitus being a chronic metabolic disease, this chapter will provide rubrics that help to identify deep acting, constitutional remedies. In this clinical trial, using of two groups (1) Based on totality formation of rubrics from constitutional chapter of Murphy Repertory (2)Based on totality formation of Murphy Repertory So, my research is based on clinical relevance of rubrics of chapter constitution from Homeopathic Medical Repertory by Robin Murphy for totality formation and remedy selection for patient with type 2 Diabetes Mellitus of age 35 to 70 years in study duration of 9 months. |