Regional anaesthesia techniques have advantages including excellent pain control, reduced side- effects, and shortened stay in the post anaesthesia care unit. Ultrasound guided regional blocks are considered safer with better success rates. Supraclavicular block has high efficacy for providing anaesthesia in upper limb surgeries. Levobupivacaine with lesser cardiac side effects is the preferred local anaesthetic agent. Dexmedetomidine and Fentanyl is used to reduce the onset time, prolong the analgesic, and motor blockade effect without the systemic side effects and reduce total dose of local anesthetic requirement. Here, in our study we determine the onset and duration of analgesia and compare the hemodynamic parameters with two different drugs of Dexmedetomidine and Fentanyl with 0.5% Levobupivacaine. We also try to find any adverse reaction to the study drugs. A total of 100 patients undergoing upper limb surgeries will be divided into two groups: Group A and Group B by block randomization. Group A will receive 19 ml of 0.5% Levobupivacaine with 1 ml of 0.5mcg/kg Dexmedetomidine and Group B will receive 19 ml of 0.5% Levobupivacaine with 1 ml of 0.5mcg/kg Fentanyl. Duration of analgesia, onset of sensory and motor block, time requirement of rescue analgesia will be studied. Hemodynamic parameters and adverse effects will be recorded. The findings and observations made during the entire study will be tabulated, graphically depicted whenever possible, statistically analysed and inference will be drawn.