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CTRI Number  CTRI/2026/02/103278 [Registered on: 09/02/2026] Trial Registered Prospectively
Last Modified On: 08/02/2026
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Drug
Surgical/Anesthesia 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   Patient came to the hospital for upper limb surgeries and we used Brachial plexus block using ultrasound guided retroclavicular approach in one group and ultrasound guided infraclavicular approach in another group  
Scientific Title of Study   Retroclavicular vs infraclavicular approaches for ultrasound guided brachial block A comparative analysis for upper limb surgeries 
Trial Acronym  Nil 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Patel Arth Harshadbhai  
Designation  PG 1st year Resident  
Affiliation  Mahatma Gandhi Medical College Hospital  
Address  Department of Anaesthesia Mahatma Gandhi Medical College Hospital Sitapur Jaipur

Jaipur
RAJASTHAN
302022
India 
Phone  9067658689  
Fax    
Email  contact2arth@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Mangilal Deganwa 
Designation  Professor 
Affiliation  Mahatma Gandhi Medical College Hospital  
Address  Department of Anaesthesia Mahatma Gandhi Medical College Hospital Sitapur Jaipur

Jaipur
RAJASTHAN
302022
India 
Phone  9871495240  
Fax    
Email  mangilaldeganwa0606@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Dr Mangilal Deganwa 
Designation  Professor 
Affiliation  Mahatma Gandhi Medical College Hospital  
Address  Department of Anaesthesia Mahatma Gandhi Medical College Hospital Sitapur Jaipur

Jaipur
RAJASTHAN
302022
India 
Phone  9871495240  
Fax    
Email  mangilaldeganwa0606@gmail.com  
 
Source of Monetary or Material Support  
MAHATMA GANDHI MEDICAL COLLEGE AND HOSPITAL 
 
Primary Sponsor  
Name  Mahatma Gandhi Medical College Hospital  
Address  Department of Anaesthesia Mahatma Gandhi Medical College Hospital Sitapur Jaipur India 302022 
Type of Sponsor  Private medical college 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
DR ARTH PATEL  Mahatma Gandhi Medical College and Hospital  Department of Anaesthesia 2nd floor OT complex Sitapura Jaipur 302022
Jaipur
RAJASTHAN 
9067658689

contact2arth@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
IECMGMCH  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  , (1) ICD-10 Condition: M848||Other disorders of continuity of bone,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Comparator Agent  Infraclavicular brachial plexus block  Group B : receive Infraclavicularultrasound guided Brachial Plexus Block approach-0.5% Levobupivacaine15mL + Dexona(8mg) 2mL The total duration of procedure is until the requirement of first rescue analgesia or first 24 hours of surgery 
Intervention  Retroclavicular Brachial Plexus Block  Group A : will receive Retroclavicular ultrasound guided Brachial plexus Block approach- 0.5% Levobupivacaine 18mL + Dexona (8mg) 2mL (total 20 ml) The total duration of procedure is until the requirement of first rescue analgesia or first 24 hours of surgery 
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  65.00 Year(s)
Gender  Both 
Details  1. Patients with ASA grade I/II
2. Elective upper limb surgeries (elbow, forearm and hand surgeries) 
 
ExclusionCriteria 
Details  1 Any bleeding disorder or patient on anticoagulants.
2. Neurological deficits involving brachial plexus.
3. History of drug allergy.
.4 Local infection at the injection site.
.5 Patients on any sedatives or antipsychotics.
6. History of alcohol and drug abuse.
7. Pregnant and lactating females. 
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   Other 
Blinding/Masking   Participant Blinded 
Primary Outcome  
Outcome  TimePoints 
1. To compare time taken from needle entry to installation of drug.
2. To compare the time of drug deposition ot complete blockade. 
Motor blockade scale at 0,5,10,15,20,25,30 mins 
 
Secondary Outcome  
Outcome  TimePoints 
1. To study complications associated with either technique.
2. To study the conversion to general anaesthesia.
3. To study the need for rescue analgesia 
Motor blockade scale at 0,5,10,15,20,25,30 mins. 
 
Target Sample Size   Total Sample Size="80"
Sample Size from India="80" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   Phase 2/ Phase 3 
Date of First Enrollment (India)   02/03/2026 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

Peripheral nerve block is always a safe alternative to general anaesthesia. Patient remains awake oriented  and with intact airway reflexes throughout the procedure. In addition it offers a better preservation of mental functions in elderly decreased risk of aspiration due to intact pharyngeal and laryngeal reflexes avoids difficult intubation decreases postoperative complications associated with intubation and provide better postoperative analgesia without undue sedation facilitating early mobilization and discharge. 

Brachial Plexus block is administered by various approaches viz. supraclavicular infraclavicular interscalenous perivascular subclavian and axillary routes for upper limb surgeries.

The Infraclavicular block is achieved by injecting local anesthetic around the cords of the brachial plexus which are located in the infraclavicular fossa. 

It’s commonly used for procedures on the elbow, forearm, wrist, and hand, especially when other approaches like the axillary block are difficult due to patient positioning or other factors.

Compared to other brachial plexus blocks the infraclavicular approach may offer better coverage of the upper arm and easier catheter placement for continuous nerve blocks. It also avoids some of the respiratory complications associated with supraclavicular and interscalene blocks.

The retroclavicular refers to the needle insertion point, which is posterior and deep to the clavicle rather than directly under it as in some other infraclavicular approaches.The patient is typically positioned supine with their head turned away from the side being blocked and a bump under their back to depress the shoulder and clavicle.The needle is inserted 1-2 cm posterior to the clavicle in the supraclavicular fossa kept parallel to the floor.The needle is advanced until it contacts the clavicle then walked off its undersurface, and hydrodissection is used to create space around the posterior cord and artery before injecting the local anesthetic.

Retroclavicular approach provides better needle visualization and lesser time for administration of brachial plexus block. Lesser chances of block related complication.

 
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