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CTRI Number  CTRI/2026/01/100324 [Registered on: 05/01/2026] Trial Registered Prospectively
Last Modified On: 19/03/2026
Post Graduate Thesis  No 
Type of Trial  Interventional 
Type of Study   Surgical/Anesthesia 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   A Study Comparing Two Methods of Flexible Scope Guided Nasal Breathing Tube Placement to Improve Successful Intubation During elective Surgery 
Scientific Title of Study   Comparison of Endotracheal Tube as a Conduit Versus the Conventional Technique for Flexible Intubating Video Endoscope Guided Nasotracheal Intubation, A Randomized Controlled Trial 
Trial Acronym  nil 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Rajesh Kumar 
Designation  Assistant Professor 
Affiliation  All India Institute Of Medical Science 
Address  Room no - 512, OT complex ,5th Floor ,Dept. of anaesthesiology, All India Institute Of Medical Science, Patna ,Bihar
Department Of Anaesthesiology ,All India Institute Of Medical Science, Patna ,Bihar
Patna
BIHAR
801507
India 
Phone  9431857279  
Fax    
Email  rajesh2k3dmc@gmail.com  
 
Details of Contact Person
Scientific Query  
Name  Dr Rajesh Kumar 
Designation  Assistant Professor 
Affiliation  All India Institute Of Medical Science 
Address  Room no - 512, OT complex ,5th Floor ,Dept. of anaesthesiology, All India Institute Of Medical Science, Patna ,Bihar
Department Of Anaesthesiology ,All India Institute Of Medical Science, Patna ,Bihar
Patna
BIHAR
801507
India 
Phone  9431857279  
Fax    
Email  rajesh2k3dmc@gmail.com  
 
Details of Contact Person
Public Query  
Name  Dr Rajesh Kumar 
Designation  Assistant Professor 
Affiliation  All India Institute Of Medical Science 
Address  Room no - 512, OT complex ,5th Floor ,Dept. of anaesthesiology, All India Institute Of Medical Science, Patna ,Bihar
Department Of Anaesthesiology ,All India Institute Of Medical Science, Patna ,Bihar
Patna
BIHAR
801507
India 
Phone  9431857279  
Fax    
Email  rajesh2k3dmc@gmail.com  
 
Source of Monetary or Material Support  
All India Institute of Medical Science ,Patna,Bihar,India Pin Code 801507 
 
Primary Sponsor  
Name  AIIMS PATNA  
Address  All India Institute of Medical Science ,Patna, Bihar, India Pin Code 801507 
Type of Sponsor  Government medical college 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Rajesh Kumar  All India Institute of Medical Science  Room no-512, 5th floor, OT complex Department of Anaesthesiology AIIMS,Patna Phulwarisarif, Patna, Bihar Pin - 801507 Patna BIHAR
Patna
BIHAR 		 09431857279

rajesh2k3dmc@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethics Committee, All India Institute of Medical Science, Patna  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: O||Medical and Surgical,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  endotracheal tube as conduit technique  In the endotracheal tube as conduit technique, a properly sized endotracheal tube is first inserted through the selected nostril up to the nasopharynx, and the flexible intubating video endoscope is passed through its lumen. The endoscope is advanced under vision to identify the vocal cords and carina, after which the endotracheal tube is gently railroaded into the trachea. Successful intubation is confirmed by direct visualisation of the carina and the appearance of a consistent end tidal carbon dioxide waveform. 
Comparator Agent  standard technique  In the standard technique, the endotracheal tube is pre mounted over the flexible intubating video endoscope and the combined assembly is introduced through the nostril.The endoscope is advanced under vision through the vocal cords to the carina, after which the endotracheal tube is railroaded into the trachea and the cuff inflated. Correct tube placement is confirmed by direct visualisation of the carina and a consistent end tidal carbon dioxide waveform, with the tube secured 4 cm above the carina 
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  60.00 Year(s)
Gender  Both 
Details  Patients planned for elective surgery under general anesthesia require nasal intubation with ASA grade 1 and 2 
 
ExclusionCriteria 
Details  1.Known bleeding disorders
2.Base of skull fracture or any contraindication to nasal intubation
3.History of drug or latex allergy
4.Uncontrolled hypertension or Diagnosed ischemic heart disease
5.Pregnancy and breast feeding women 
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   Sequentially numbered, sealed, opaque envelopes 
Blinding/Masking   Participant Blinded 
Primary Outcome  
Outcome  TimePoints 
To compare the total intubation time between the ETT-as-conduit technique and the
conventional method of FIVE-guided nasotracheal intubation. 		 To compare the total intubation time between the ETT-as-conduit technique and the
conventional method of FIVE-guided nasotracheal intubation. 
 
Secondary Outcome  
Outcome  TimePoints 
1.To compare the hemodynamic variation during the procedure.
2.To compare no of attempt and the incidence of nasal bleeding associated with each technique. 		 During surgery 
 
Target Sample Size   Total Sample Size="70"
Sample Size from India="70" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   Phase 3/ Phase 4 
Date of First Enrollment (India)   20/01/2026 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="0"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)
Modification(s)  		 Not Applicable 
Recruitment Status of Trial (India)  Open to Recruitment 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary   Nasotracheal intubation using a flexible intubating video endoscope is commonly performed in patients undergoing head and neck and maxilofacial surgeries. However, the technique can be technically challenging and the time-consuming, particularly in patients with limited airspace and difficult anatomy. Various adjuncts have been described to facilitate endoscope guided nasotracheal intubation, including the use of an endotracheal tube as a conduit. This randomised controlled trial aims to compare the effectiveness and safety of using an endotracheal tube as a conduit versus the conventional technique for flexible intubating endoscope-guided nasotracheal intubation in adult patients. Participants will be randomly allocated to one of the two study groups. The primary outcome will be the time required to achieve successful nasotracheal intubation. Secondary outcome will be first attempt success rate ease of intubation, mucosal trauma and bleeding. Successful intubation will be confirmed by the presence of a consistent end tidal carbon dioxide waveform. Failed intubation will be managed according to standard institutional airway management protocols.The finding of the study are expected to provide evidence-based guidance on the optimal technique for flexible endoscope-guided nasotracheal intubation, potentially improving procedural efficiency and patient safety. 
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