Current clinical study is single arm clinical trial to evaluate the combined effectiveness of Chitrakadi Vati and Avipathi Churnam-two Ayurveda formulations in the management of hypothyroidism.In the present study, an open label single arm clinical trial at IPD basis will be done with pre and post-test design for the included 30 patients.Here Chitrakadi Vati 250 mg twice daily in the morning and night will be administered before food with ushnodaka as anupana for the first 8 days.On the 9^th day Koshta Shuddhi (administration of laxative medicine for internal purification)    as a part of sroto sodhana will be done with Avipathi Churnam in a dose of 10gms with Honey in early morning in empty stomach.Samsarjana karma (wholesome diet) will be observerd for the next day.The patient will be discharged with Chitrakadi vati for the next 30 days.After 30 days,the second course of Koshta Shuddhi (administration of laxative medicine for internal purification)  will be done with Avipathi churnam in the same dose i.e on the 40^th day.On the next day samsarjana karma (wholesome diet) will be observed.The patient will be discharged with Chitrakadi vati to be taken in the same dose as before for 30 days.After 30 days i.e on the 70^th day last course of Koshta Shuddhi will be done with Avipathi Churnam in the same dose as before.On the next day samsarjana karma will be observed and the patient will be discharged with Chitrakadi vati for the next 20 days i.e till the 90^th day.Hence the entire treatment will be completed in 90  days.

The patient will be assessed on the 1^st day and 90^th day with investigations like Thyroid profile and BMI. The signs and symptoms will be assessed using Billewicz scoring system on the 1^st day, 10^th day, 41^st day, 71^st day and on the 90^th  day. Assessment would be done based on subjective and objective parameters and would also be monitored for Adverse Drug Reactions or Adverse Drug Effects or other concurrent illness