FULL DETAILS (Read-only)  -> Click Here to Create PDF for Current Dataset of Trial
CTRI Number  CTRI/2026/01/100378 [Registered on: 06/01/2026] Trial Registered Prospectively
Last Modified On: 29/12/2025
Post Graduate Thesis  No 
Type of Trial  Observational 
Type of Study   Prospective Observational study 
Study Design  Other 
Public Title of Study   A study to see results of CPR in Adult Cancer Patients Who Have Cardiac Arrests in the Hospital 
Scientific Title of Study   Outcomes of in-hospital cardiopulmonary resuscitation for cardiac arrests in adult patients with cancers 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
901230_V1.0 dated 22.09.2025  Protocol Number 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Shilpushp Bhosale  
Designation  Professor and Head, Division of Critical Care Medicine, ACTREC  
Affiliation  Advanced Centre for Treatment, Research and Education in Cancer 
Address  Department of Anaesthesia Critical Care and Pain, Sector 22 Utsav Chowk CISF Rd Owe Camp, ACTREC, Kharghar Navi Mumbai

Mumbai
MAHARASHTRA
410210
India 
Phone  9619310657  
Fax    
Email  shilbhosale@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Shilpushp Bhosale  
Designation  Professor and Head, Division of Critical Care Medicine, ACTREC  
Affiliation  Advanced Centre for Treatment, Research and Education in Cancer 
Address  Department of Anaesthesia Critical Care and Pain, Sector 22 Utsav Chowk CISF Rd Owe Camp, ACTREC, Kharghar Navi Mumbai

Mumbai
MAHARASHTRA
410210
India 
Phone  9619310657  
Fax    
Email  shilbhosale@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Dr Shilpushp Bhosale  
Designation  Professor and Head, Division of Critical Care Medicine, ACTREC  
Affiliation  Advanced Centre for Treatment, Research and Education in Cancer 
Address  Department of Anaesthesia Critical Care and Pain, Sector 22 Utsav Chowk CISF Rd Owe Camp, ACTREC, Kharghar Navi Mumbai

Mumbai
MAHARASHTRA
410210
India 
Phone  9619310657  
Fax    
Email  shilbhosale@gmail.com  
 
Source of Monetary or Material Support  
Dept of Anaesthesia, Critical care and Pain, OT complex, Seventh floor, RRS Building, ACTREC, Navi Mumbai - 410210 India 
 
Primary Sponsor  
Name  Tata Memorial Centre  
Address  Department of Anaesthesia Critical Care and Pain, ACTREC, Navi Mumbai - 410210 
Type of Sponsor  Research institution and hospital 
 
Details of Secondary Sponsor  
Name  Address 
NA  NA 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Shilpushp Bhosale   Tata Memorial Centre  Department of Anaesthesia Critical Care and Pain, ACTREC, Kharghar, Navi Mumbai - 410210
Mumbai
MAHARASHTRA 
9619310657

shilbhosale@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethics Committee: III   Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: C00-D49||Neoplasms,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Nil  Nil 
Comparator Agent  Nil  Nil 
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  98.00 Year(s)
Gender  Both 
Details  All Adult patients (older than 18 years) in whom Code blue activated 
 
ExclusionCriteria 
Details  Pediatric Patients (less than 18 years) will be excluded 
 
Method of Generating Random Sequence   Not Applicable 
Method of Concealment   Not Applicable 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
Incidence of Cardiac arrest Code blue calls in hospital   Day 1 
 
Secondary Outcome  
Outcome  TimePoints 
1. Incidence of ROSC in cardiac arrest patients.
2. Factors associated with cardiac arrests.
3. Patient survival, neurological recovery, organ support requirements, LOS-ICU, LOS-hospital.
 
Day 1 
 
Target Sample Size   Total Sample Size="50"
Sample Size from India="50" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   12/01/2026 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

Cardiac page or code blue is an intensive care service, which once activated, mobilizes a dedicated team to the site of cardiac arrest with all the equipment required for resuscitation. Successful resuscitation requires early recognition, immediate action by the parent team till ICU team arrives, high quality ACLS and CPR, efficient transport to the ICU.

The underlying pathology plays the most important role in determining the outcome of the oncology patient. This is the reason that many times revival at site does not translate into survival at hospital discharge. This may be a reflection of ill-sustained organ function and irreversible damage setting in before, during or post cardiac arrest.

Survival to in-hospital cardiac arrest is reported at 46 percent at discharge as per a recent systematic review. The National Registry of Cardiopulmonary Resuscitation in the United States suggests 27 percent survival to discharge, but only 15.7 percent with good neurological outcome.

Unique to cancer setting. Cancer patients often travel from distant places causing delay in presentation. Acute respiratory failure and sepsis are common causes of ICU admissions in these immunocompromised patients. Lack of do not resuscitate DNR orders may allow CPR in unwarranted situations.

Important clarification. This study will have no direct contact with patients. Data will only be collected from existing code blue forms and electronic medical records EMR.

Definitions. Cardiac arrest. 1 No palpable pulse, 2 No detectable blood pressure, 3 No effective respiration, 4 Loss of consciousness. ROSC. Maintenance of spontaneous circulation for at least 1 hour following resuscitation effort.

 
Close