| CTRI Number |
CTRI/2026/01/100378 [Registered on: 06/01/2026] Trial Registered Prospectively |
| Last Modified On: |
29/12/2025 |
| Post Graduate Thesis |
No |
| Type of Trial |
Observational |
|
Type of Study
|
Prospective Observational study |
| Study Design |
Other |
|
Public Title of Study
|
A study to see results of CPR in Adult Cancer Patients Who Have Cardiac Arrests in the Hospital |
|
Scientific Title of Study
|
Outcomes of in-hospital cardiopulmonary resuscitation for cardiac arrests in adult patients with cancers |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| 901230_V1.0 dated 22.09.2025 |
Protocol Number |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Shilpushp Bhosale |
| Designation |
Professor and Head, Division of Critical Care Medicine, ACTREC |
| Affiliation |
Advanced Centre for Treatment, Research and Education in Cancer |
| Address |
Department of Anaesthesia Critical Care and Pain, Sector 22 Utsav Chowk CISF Rd Owe Camp, ACTREC, Kharghar Navi Mumbai
Mumbai MAHARASHTRA 410210 India |
| Phone |
9619310657 |
| Fax |
|
| Email |
shilbhosale@gmail.com |
|
Details of Contact Person Scientific Query
|
| Name |
Dr Shilpushp Bhosale |
| Designation |
Professor and Head, Division of Critical Care Medicine, ACTREC |
| Affiliation |
Advanced Centre for Treatment, Research and Education in Cancer |
| Address |
Department of Anaesthesia Critical Care and Pain, Sector 22 Utsav Chowk CISF Rd Owe Camp, ACTREC, Kharghar Navi Mumbai
Mumbai MAHARASHTRA 410210 India |
| Phone |
9619310657 |
| Fax |
|
| Email |
shilbhosale@gmail.com |
|
Details of Contact Person Public Query
|
| Name |
Dr Shilpushp Bhosale |
| Designation |
Professor and Head, Division of Critical Care Medicine, ACTREC |
| Affiliation |
Advanced Centre for Treatment, Research and Education in Cancer |
| Address |
Department of Anaesthesia Critical Care and Pain, Sector 22 Utsav Chowk CISF Rd Owe Camp, ACTREC, Kharghar Navi Mumbai
Mumbai MAHARASHTRA 410210 India |
| Phone |
9619310657 |
| Fax |
|
| Email |
shilbhosale@gmail.com |
|
|
Source of Monetary or Material Support
|
| Dept of Anaesthesia, Critical care and Pain, OT complex, Seventh floor, RRS Building, ACTREC, Navi Mumbai - 410210 India |
|
|
Primary Sponsor
|
| Name |
Tata Memorial Centre |
| Address |
Department of Anaesthesia Critical Care and Pain, ACTREC, Navi Mumbai - 410210 |
| Type of Sponsor |
Research institution and hospital |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Shilpushp Bhosale |
Tata Memorial Centre |
Department of Anaesthesia Critical Care and Pain, ACTREC, Kharghar, Navi Mumbai - 410210 Mumbai MAHARASHTRA |
9619310657
shilbhosale@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional Ethics Committee: III |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: C00-D49||Neoplasms, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Intervention |
Nil |
Nil |
| Comparator Agent |
Nil |
Nil |
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
98.00 Year(s) |
| Gender |
Both |
| Details |
All Adult patients (older than 18 years) in whom Code blue activated |
|
| ExclusionCriteria |
| Details |
Pediatric Patients (less than 18 years) will be excluded |
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
| Incidence of Cardiac arrest Code blue calls in hospital |
Day 1 |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
1. Incidence of ROSC in cardiac arrest patients.
2. Factors associated with cardiac arrests.
3. Patient survival, neurological recovery, organ support requirements, LOS-ICU, LOS-hospital.
|
Day 1 |
|
|
Target Sample Size
|
Total Sample Size="50" Sample Size from India="50"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
12/01/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1" Months="0" Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Cardiac page or code blue is an intensive care service, which once activated, mobilizes a dedicated team to the site of cardiac arrest with all the equipment required for resuscitation. Successful resuscitation requires early recognition, immediate action by the parent team till ICU team arrives, high quality ACLS and CPR, efficient transport to the ICU. The underlying pathology plays the most important role in determining the outcome of the oncology patient. This is the reason that many times revival at site does not translate into survival at hospital discharge. This may be a reflection of ill-sustained organ function and irreversible damage setting in before, during or post cardiac arrest. Survival to in-hospital cardiac arrest is reported at 46 percent at discharge as per a recent systematic review. The National Registry of Cardiopulmonary Resuscitation in the United States suggests 27 percent survival to discharge, but only 15.7 percent with good neurological outcome. Unique to cancer setting. Cancer patients often travel from distant places causing delay in presentation. Acute respiratory failure and sepsis are common causes of ICU admissions in these immunocompromised patients. Lack of do not resuscitate DNR orders may allow CPR in unwarranted situations. Important clarification. This study will have no direct contact with patients. Data will only be collected from existing code blue forms and electronic medical records EMR. Definitions. Cardiac arrest. 1 No palpable pulse, 2 No detectable blood pressure, 3 No effective respiration, 4 Loss of consciousness. ROSC. Maintenance of spontaneous circulation for at least 1 hour following resuscitation effort. |