| CTRI Number |
CTRI/2025/12/099765 [Registered on: 23/12/2025] Trial Registered Prospectively |
| Last Modified On: |
23/12/2025 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Physiotherapy (Not Including YOGA) |
| Study Design |
Randomized, Parallel Group, Active Controlled Trial |
|
Public Title of Study
|
A study comparing two physiotherapy techniques to reduce pain, increase movement, and improve daily activities in people with upper crossed syndrome. |
|
Scientific Title of Study
|
Comparison between effectiveness of muscle energy technique and active release technique on pain, range of motion and functional disability in patients with upper crossed syndrome - a randomised controlled trial |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Anwiksha Mahadik |
| Designation |
PG Student |
| Affiliation |
TMVs Lokmanya Tilak College of Physiotherapy |
| Address |
TMVs Lokmanya Tilak College of Physiotherapy, Third Floor, Department of Musculoskeletal Physiotherapy, Tilak Maharashtra Vidyapeeth, J Block ,Sector 14, Near Raghunath Vihar, Kharghar, Navi Mumbai
Raigarh
MAHARASHTRA
410210
India |
| Phone |
8355915715 |
| Fax |
|
| Email |
anwikshamahadik@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Deepali Rathod |
| Designation |
Associate professor |
| Affiliation |
TMVs Lokmanya Tilak College of Physiotherapy |
| Address |
TMVs Lokmanya Tilak College of Physiotherapy, Third Floor, Department of Musculoskeletal Physiotherapy, Tilak Maharashtra Vidyapeeth, J Block ,Sector 14, Near Raghunath Vihar, Kharghar, Navi Mumbai
Raigarh
MAHARASHTRA
410210
India |
| Phone |
9082390287 |
| Fax |
|
| Email |
dr.deepali.pankaj.rathod@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Dr Deepali Rathod |
| Designation |
Associate professor |
| Affiliation |
TMVs Lokmanya Tilak College of Physiotherapy |
| Address |
TMVs Lokmanya Tilak College of Physiotherapy, Third Floor, Department of Musculoskeletal Physiotherapy, Tilak Maharashtra Vidyapeeth, J Block ,Sector 14, Near Raghunath Vihar, Kharghar, Navi Mumbai
Raigarh
MAHARASHTRA
410210
India |
| Phone |
9082390287 |
| Fax |
|
| Email |
dr.deepali.pankaj.rathod@gmail.com |
|
|
Source of Monetary or Material Support
|
| TMVs Lokmanya Tilak college of physiotherapy |
|
|
Primary Sponsor
|
| Name |
TMVs Lokmanya Tilak college of physiotherapy |
| Address |
TMVs Lokmanya Tilak College of Physiotherapy, Third Floor, Department of Musculoskeletal Physiotherapy, Tilak Maharashtra Vidyapeeth, J Block ,Sector 14, Near Raghunath Vihar, Kharghar, Navi Mumbai |
| Type of Sponsor |
Research institution |
|
|
Details of Secondary Sponsor
|
| Name |
Address |
| TMVs Lokmanya Tilak College of Physiotherapy |
TMVs Lokmanya Tilak College of Physiotherapy, Third Floor, Department of Musculoskeletal Physiotherapy, Tilak Maharashtra Vidyapeeth, J Block ,Sector 14, Near Raghunath Vihar, Kharghar, Navi Mumbai |
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Anwiksha Mahadik |
TMVs Lokmanya Tilak College of Physiotherapy |
TMVs Lokmanya Tilak College of Physiotherapy, Third Floor, Department of Musculoskeletal Physiotherapy, Tilak Maharashtra Vidyapeeth, J Block ,Sector 14, Near Raghunath Vihar, Kharghar, Navi Mumbai
Raigarh
MAHARASHTRA |
8355915715
anwikshamahadik@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| TMVs Lokmanya Tilak College of Physiotherapy Institutional ethics committee (Academics) |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: M799||Soft tissue disorder, unspecified, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Comparator Agent |
Active Release technique |
Active Release technique addresses trigger point in upper trapezius muscle.
Conventional treatment includes scapular strengthening exercises 10 repetition 3 sets. Above treatment is given twice a week for 6 week |
| Intervention |
Muscle Energy Technique |
Muscle Energy Technique given for upper trapezius muscle. Conventional treatment includes scapular strengthening exercises 10 repetition 3 sets. Above treatment is given twice a week for 6 week. |
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
45.00 Year(s) |
| Gender |
Both |
| Details |
Patients with uppercrossed syndrome |
|
| ExclusionCriteria |
| Details |
fracture of cervical spine
Myelopathy
Thoracic outlet syndrome |
|
|
Method of Generating Random Sequence
|
Adaptive randomization, such as minimization |
|
Method of Concealment
|
Alternation |
|
Blinding/Masking
|
Participant Blinded |
|
Primary Outcome
|
| Outcome |
TimePoints |
Visual Analogue Scale,
Neck lateral Flexion Range of motion using Goniometer,
Neck Disability Index |
6 week |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| NIL |
NIL |
|
|
Target Sample Size
|
Total Sample Size="64"
Sample Size from India="64"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
Phase 3 |
|
Date of First Enrollment (India)
|
15/01/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="6"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
This study is a randomised control trial to study comparison between effectiveness of muscle energy technique and active release technique on pain, range of motion and functional disability in patient with upper crossed syndrome. This study includes 64 patients diagnosed with upper crossed syndrome within the age limit 18 to 45 years. The outcome measures used in the above study are visual analogue scale, range of motion of neck lateral flexion using goniometer and neck disability index.In the previous studies there is limited literature about the long term effects of these two techniques.There is little evidence regarding the use of the two techniques in upper crossed syndrome along with conventional protocol.Using these two manual techniques we will offer an opportunity for the nervous system and the musculoskeletal system to reset and see which one works better.
|